David J Nagel publish and article in Infinite Energy about "Questions About Lattice Enabled Nuclear Reactions: Engineering, Commercialization and Applications".
a very detailed review of engineering and applications challenges...
http://www.infinite-energy.com/images/pdfs/NagelIE120.pdf
Note that it is in the latest issue of Infinite Energy
http://www.infinite-energy.com/index.html
many other articles available inside.