The Playground

    Covid infections in the UK are up by more than 40%, the latest weekly Office for National Statistics (ONS) figures suggest.

    Around 1.4m people in the UK had coronavirus in the week ending 11 June, up from around 990,000 the week before.

    The fast-spreading subvariants of Omicron - called BA.4 and BA.5 - are behind some of the new infections, according to the ONS.

    In total more than 179,000 people have died in the UK within 28 days of a positive Covid test, but the number of people with Covid-19 on their death certificates is over 196,000.

    A Covid vaccination programme has so far reached nine in 10 people aged 12 and over with a first dose.

    Covid is making flu and other common viruses act in unfamiliar ways - The Washington Post


    Interesting article. Especially so when the headline implies it is COVID alone responsible for these anomalies. Yet in reading the article:


    Researchers have a rare opportunity to figure out whether behavioral changes like stay-at-home orders, masking and social distancing are responsible for the viral shifts, and what evolutionary advantage SARS CoV-2 may be exercising over its microscopic rivals.


    So beyond the headline, where few read, they admit these obvious anomalies may also result from manmade policies. It will be interesting to see if the politics ever allows the science to decide, and if it does will science be brave enough to rally around their consensus.


    The reason I brought this up is that I just recovered from the worse flu I ever went through. This is summer here in the northern hemisphere BTW. My grandkids have been cycling through every virus in the medical literature, including RSV, and coronaviruses I never heard of before.

    Pfizer crap "vaccine" : https://jamanetwork.com/journa…08-43a5-ab1f-c9608a26d112


    At least for seniors...


    Compared with the mRNA-1273 group, the BNT162b2 group had an excess per 10 000 persons of 10.9 events (95% CI, 1.9-17.4 events) of ischemic stroke, 14.8 events (95% CI, 7.9-21.8 events) of myocardial infarction, 11.3 events (95% CI, 3.4-17.7 events) of other thromboembolic events, and 17.1 events (95% CI, 8.8-30.2 events) of kidney injury. Estimates were largely similar among subgroups defined by age (<40, 40-69, and ≥70 years) and race (Black, White), but there were higher magnitudes of risk differences of ischemic stroke among older persons and White persons, kidney injury among older persons, and other thromboembolic events among Black persons.

    Quote from Shane D.

    Covid is making flu and other common viruses act in unfamiliar ways - The Washington Post

    At one point last month, children were admitted to Yale New Haven Children’s Hospital with a startling range of seven respiratory viruses. They had adenovirus and rhinovirus, respiratory syncytial virus and human metapneumovirus, influenza and parainfluenza, as well as the coronavirus — which many specialists say is to blame for the unusual surges.


    Why just now? And why just children? Children rely on innate immunity for which RNA therapy is immunosuppressive. So their body does not react on arrivals of new viruses in time.... See also:

    Quote from Wyttenbach

    RNA therapy is immunosuppressive

    For those interested in the complexities of Nature..

    and BigPharma's perversion of it

    Highlights

    •

    mRNA vaccines promote sustained synthesis of the SARS-CoV-2 spike protein.

    •

    The spike protein is neurotoxic, and it impairs DNA repair mechanisms.

    •

    Suppression of type I interferon responses results in impaired innate immunity.

    •

    The mRNA vaccines potentially cause increased risk to infectious diseases and cancer.

    •

    Codon optimization results in G-rich mRNA that has unpredictable complex effects.

    Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs
    The mRNA SARS-CoV-2 vaccines were brought to market in response to the public health crises of Covid-19. The utilization of mRNA vaccines in the conte…
    www.sciencedirect.com

    The dirtbag continues with his swindle maintenance Team, ineffectuality attempting to keep the flailing confidence routine from languishing further into the (quite correct) dismay, disillusionment and seeking legal reprisal terminus. Still zero citations for the SLuRPI paper…(which in total have dropped by two since) but nobody chirps up in print on JoNP…


    2022-06-24 00:58 Giovanna Gambirasio 

    Dear Dr Andrea Rossi,

    Congratulations for the highest scientific echelons ( Nobel Price laureates, Physics Professors and Researchers, Engineering Professors, Senior Scientists ) that recommended the paper

    http://www.researchgate.net/publication/33060I653_E-Cat_SK_and_long_range_particle_interactions

    Hundreds of these top level peer reviewers have recommended this paper, which collected more than 100000 readings: this is a fact.

    Ad majora,

    Giovanna Gambirasio

    International Journal of Hydrogen Energy

    Volume 46, Issue 27, 19 April 2021, Pages 14581-14591

    International Journal of Hydrogen Energy


    "Nanogap Plasmonic Field Enhancement on Hydrogen-Absorbing Transition Metals"


    Nanogap plasmonic field enhancement on hydrogen-absorbing transition metals
    The electromagnetic field enhancement factors by gap plasmons between two spherical metal particles are calculated for hydrogen-absorbing transition m…
    www.sciencedirect.com


    Abstract

    The electromagnetic field enhancement factors by gap plasmons between two spherical metal particles are calculated for hydrogen-absorbing transition metals Pd, Ti, and Ni, and reference noble metals Au, Ag, and Cu, in air, H2, or vacuum, and H2O. The dependence of the field enhancement factors on the metal species, the field wavelength, the electric field polarization, the separation of the two metal particles, and the observing location is systematically investigated. Field enhancement is observed significantly large in the gap of two metal particles and sensitive to the particle separation, but insensitive to the position in the gap, indicating a geometric flexibility for applications. The spectral peak field enhancement factors for Pd, Ti, and Ni do not compete with those for Au, Ag, and Cu, but do in the microwave regime. For the electric field parallel to the bipartite alignment, the field enhancement factors in the gap for Pd, Ti, and Ni are observed as large as several hundred and ten thousand for the separation-to-radius ratios of 0.1 and 0.01, respectively, for a wide wavelength region spanning from the visible to the infrared.


    The large field enhancements in the nanogaps of hydrogen-absorbing transition metals observed in this study can potentially be utilized for various energy applications, such as hydrogen storage, sensing, and nuclear fusion.


    In practical metallic material systems, it is important to account for such a gap-plasmon effect because nanoscale gaps commonly exist, for instance, on rough metal surfaces and in metal particle aggregates.

    Quote from Zephir_AWT

    At one point last month, children were admitted to Yale New Haven Children’s Hospital with a startling range of seven respiratory viruses. They had adenovirus and rhinovirus, respiratory syncytial virus and human metapneumovirus, influenza and parainfluenza, as well as the coronavirus — which many specialists say is to blame for the unusual surges.


    Why just now? And why just children? Children rely on innate immunity for which RNA therapy is immunosuppressive. So their body does not react on arrivals of new viruses in time.... See also:

    Worth pointing out the obvious multiple fallacies in the anti-vaxxer rhetoric (yes - this is that).


    We all know that an increase in all infectious diseases, and loss of immunity especially amongst young children who have never had it, is expected after lock-downs. And, yes, this is one of the many long-term costs we bear from lockdowns and how that trade-off goes is irrelevant. In democracies we count immediate danger far more than long-term disease or we would not so subsidise foods that are costing us billions in increased disease and shortening life expectancy. Equally, if we counted long-term disease we would have to treat the dangers of poverty as seriously as the dangers of a war, and states would act to protect populations from that even at a high cost.


    So this argument is specious. But I'm more interested in the other lie in this. (That is - I don't think Zephyr is lying - but I'm pretty sure some of the originators of this stuff are).


    It is obvious to any thinking person (the antivaxxers are not that) that RNA treatments are extraordinarily powerful. The injected RNA can express almost any protein using the machinery of the cells it goes into, in exactly the same way as an RNA virus (such as COVID, or Flu).


    Saying RNA treatment is immunosuppressive is like saying that organic molecules are poisonous. Well, some are, but they are also what we need to eat, and many are just inert.


    RNA treatment has actually been used to boost immune response against cancer cells (quote below from wikipedia)


    Recently, the new cancer immunotherapy, the combining of self-delivering RNA(sd-rxRNA) and adoptive cell transfer(ACT) therapy, was invented by RXi Pharmaceuticals and the Karolinska Institute. In this therapy, the sd-rxRNA eliminated the expression of immunosuppressive receptors and proteins in therapeutic immune cells so it improved the ability of immune cells to destroy the tumor cells. Then, the PD-1 targeted sd-rxRNA helped increasing the anti-tumor activity of tumor-infiltrating lymphocytes (TIL) against melanoma cells.[40][41] Based on this idea, the mRNA-4157 has been tested and passed phase I clinical trial.[42]

    Cytosolic nucleic acid-sensing pathways can enhance immune response to cancer. RIG-I agonist, stem loop RNA (SLR) 14. Tumor growth was significantly delayed and extended survival in mice. SLR14 improved antitumor efficacy of anti-PD1 antibody over single-agent treatment. SLR14 was absorbed by CD11b+ myeloid cells in the tumor microenvironment. Genes associated with immune defense were significantly up-regulated, along with increased CD8+ T lymphocytes, NK cells, and CD11b+ cells. SLR14 inhibited nonimmunogenic B16 tumor growth, leaving immune memory.[43]


    I'm not entirely how far the innate Luddism of anti-vaxxers extends. Maybe it depends on the person afflicted with this meme? Sure, just as with GMOs, RNA used medically is powerful, and with power comes danger. Just as with GMOs the danger is not in principle different from what exists anyway. GMOs mimic cross-species hybridisation. RNA therapies mimic RNA viruses - but with much less danger because they are not self-replicating or capable of evolving.


    The ire of the anti-vaxxers - in this case - descends on a pretty boring RNA vaccine - not a therapy. Vaccines do of course change the immune response, in the same way that a virus attack changes it but with fewer nasty side effects. Vaccines, other than their effect on the immune system - tend to have no long-term side effects because they are given in necessarily very small quantities.


    Anyway RNA vaccines are not immunosuppressive, far from it, except inasfar as anything that tunes the immune system to respond to a new agent changes it. They do not suppress innate immune response.


    Innate, like natural, are the sort of emotive words that anti-vaxxers like to use: "natural immunity" instead of "COVID survivor's immunity". As we now know (and knew already from Flu) survivors immunity is no panacea for COVID - Omicron BA4, BA5, as the Uk is now discovering, seems pretty resistant to it.


    T-cell immunity (which anti-vaxxers sometimes call natural immunity) is much broader than antibody-derived immunity. It is enhanced naturally after infection, and naturally (to a greater extent) after vaccination. And it is that which in the end determines whether you get seriously ill. (AB immunity, if good enough - stops you getting infected at all).


    We are lucky that the 1st gen COVID vaccines are broad enhance to give T-cell immunity against all lineages of COVID so far seen. It is why the very few people now not vaccinated are at higher risk of serious disease from omicron.


    I wish though more urgency and money was put into developing better vaccines. COVID may yet come back to bite us and we will then need them.


    THH

    I think here we are seeing more clearly Rossi's character. He is a true showman - somone who wants the plaudits of an audience - any audience - above all else.


    It would be sad except for the harm he has done to some others.

    And... another one.


    The Problem with Preprints
    Pre-print research papers circulate the internet prior to peer-review, fueling COVID-19 vaccine misinformation and conspiracies.
    www.isdglobal.org


    In late January 2022, a preprint scientific paper published on ResearchGate started circulating within online communities associated with COVID-19, vaccine-scepticism and conspiracy theories. The title reads, ‘Innate Immune Suppression by SARS-CoV-2 mRNA Vaccinations: The role of G-quadruplexes, exosomes and microRNAs’. The claims made in the abstract are quite scandalous. The research claims to prove that “vaccination, unlike natural infection, induces a profound impairment in type I interferon signaling, which has diverse adverse consequences to human health”. It continues by saying that they also identified “profound potential disturbances” related to the vaccine and that these could have a “potentially direct causal link” to a range of different health defects, including Bell’s Palsy, myocarditis, liver disease and DNA damage.

    The paper has four authors, including one name that might sound familiar given recent coverage of Joe Rogan’s platforming of COVID-19 and vaccine misinformation: Dr Peter McCullough. The paper is 35 pages long and contains over 200 citations. At a glance, it appears reputable. For those within COVID-19 and vaccine-sceptic communities, it seemed like the scientific research they were waiting for. Proof at last that the vaccines are doing more damage than good.

    In just three weeks, the paper was read almost 250,000 times on ResearchGate (a site used by academics and scientists to share research), shared across dozens of groups on Facebook and Telegram, and promoted by anti-vaccine influencers to hundreds of thousands of people. This paper is part of a wider trend observed by ISD where highly flawed ‘research’ published as preprints, undertaken by credentialed individuals with a clear bias against COVID-19 vaccines, is used to spread anti-vaccine and COVID-denial claims to an unwitting audience.

    Preprints are papers that have yet to go through the peer-review process, which is an integral element of any academic or scientific research. Peer-review normally takes place after a research paper is submitted to a journal for publication. Typically, the paper is sent out to a number of independent researchers in the same field who then scrutinise the work, including looking for flaws in the methodology, and assessing the validity of the claims laid out in the paper. The paper’s author(s) will then make revisions based on the peer-review process before the journal’s editor makes a decision on whether to publish it or not.

    And re RB's "paper" above - this is of course another example where THH's anti-vaxxer detection kit* works.


    Seneff, the lead author, is a prominent anti-vaxxer, and has no medical expertise. She is a Computer Scientist, working on HCI, language understanding, speech recognition.


    And, were she a medical scientist the extraordinarily variety of her claimed contributions to medical science, and the way that the historic ones have all been so completely debunked - again woudl trigger anti-vaxxer detection systems.


    THH


    * - ok - I can't really take credit, it is common sense and many others use it independently of me. I am juts popularising it on the thread where it seems almost unknown.

    A prominent surgeon at Johns Hopkins University, contributor to prominent publications such as the Wall Street Journal and increasingly outspoken critic of the COVID-19 vaccination process, Dr. Martin Adel Makary, MD, MPH, Professor of Surgery shared six key points that he believes the CDC (Walensky) left out of the formal announcement that parents should be aware of.



    Points for Parents to Consider


    Summary


    Discussion


    Inconclusive research


    Makary argues the studies involved with generating the data to achieve statistical significance were too small for evaluating efficacy against both mild-to-severe COVID-19 infection.


    Note, Makary reports there were “no cases of severe COVID-19 illness in either the vaccine or placebo group.”


    Consequently, Makary reminds parents that the FDA tolerated both companies’ effort to extrapolate effectiveness via measurement of antibody levels as well as reference other data from older children and adult studies.


    FDA lowers their standards for what is considered acceptable for vaccine efficacy levels necessary for approval


    By 2020, the FDA and public health agencies would authorize COVID-19 vaccines if they showed at least 50% efficacy.


    To push the approval through, Dr. Peter Marks lowered this pre-set bar, declaring, “If these vaccines seem to be mirroring efficacy in adults and just seem to be less effective against Omicron like they are for adults, we will probably still authorize.”


    Most children already have natural immunity


    According to a Feb. 2022 CDC report, 75% of children 0-17 years of age have already been infected with COVID-19. With the highly transmissible Omicron, that figure could be 80-90%.


    Makary notes, “There is absolutely zero clinical evidence to support vaccinating healthy children who already have COVID-19.” The FDA and CDC continue to ignore natural immunity measures in the real world.


    Safety data based on far too small a sample


    The small set of studies involving the youngest cohort made it nearly impossible to observe rates of rare complications such as myocarditis, which occurs in 1 in 2,650 12–17-year-old bodies after the 2nd dose. This complication has been associated with EKG changes in children and even concerning MRI findings months after recovering from myocarditis.”


    How much danger are our children actually in? Why isn’t the CDC factoring in these important considerations?



    Backing the vaccine is Dr. Eric Rubin, editor-in-chief of the New England Journal of Medicine, who said late last year: “But we’re never going to learn about how safe this vaccine is unless we start giving it. That’s just the way it goes.”


    All data indicate healthy children don’t have a high but rather very low risk of serious consequences due to COVID-19 infection


    With a considerably differing risk profile along with different drivers for vaccination as compared to obese, immunocompromised, or other children. Makary reports a German population study uncovered that all deaths in children 5-17 were those with comorbidity. He reports not one healthy child between the ages of 5 to 17 died in that country unvaccinated.


    The CDC is not being candid, forthright or sufficiently transparent with the data.


    The hubris behind the public agencies becomes too much or, put another way, the CDC and other agencies lack humility.


    For example, Walensky declared, “We now based on rigorous scientific review that vaccines can be used safely and effectively in children under 5.”


    While the review was rigorous, Makary declared, “the underlying data was not.”

    Vaccines lacking any significant efficacy but our alphabet agencies continue to approve. Payed for by your tax dollars. Total insanity!


    Neutralization Escape by SARS-CoV-2 Omicron Subvariants BA.2.12.1, BA.4, and BA.5


    https://www.nejm.org/doi/full/10.1056/NEJMc2206576


    In recent months, multiple lineages of the omicron (B.1.1.529) variant of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) have emerged,1 with subvariants BA.1 and BA.2 showing substantial escape from neutralizing antibodies.2-5 Subvariant BA.2.12.1 is now the dominant strain in the United States, and BA.4 and BA.5 are dominant in South Africa (Figure 1A). Subvariants BA.4 and BA.5 have identical sequences of the spike protein.


    We evaluated neutralizing antibody titers against the reference WA1/2020 isolate of SARS-CoV-2 along with omicron subvariants BA.1, BA.2, BA.2.12.1, and BA.4 or BA.5 in 27 participants who had been vaccinated and boosted with messenger RNA vaccine BNT162b2 (Pfizer–BioNTech) and in 27 participants who had been infected with the BA.1 or BA.2 subvariant a median of 29 days earlier (range, 2 to 113) (Tables S1 and S2 in the Supplementary Appendix, available with the full text of this letter at NEJM.org). In the vaccine cohort, participants were excluded if they had a history of SARS-CoV-2 infection or a positive result on nucleocapsid serologic analysis or if they had received another vaccine against coronavirus disease 2019 (Covid-19) or an immunosuppressive medication

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