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Quote from JedRothwell

Last year there were no vaccines! What you are saying is ridiculous. What will you say when this does not happen? I predict you will pretend you never said it.

Unless another new variant comes along, the pandemic is over in Japan, and Argentina, Israel, and every other country with a functional public health system and sane citizens. It will continue to kill hundreds of thousands of lunatics who refuse to be vaccinated.

As Japan is starting to open up its border more (e.g. allowing business and student visa arrivals) it is reasonably inevitable IMO that there will be a rise in cases. Hopefully it will keep to manageable levels.

WARNING: The following post is strictly Scientific in Nature, read at your own peril.

Technical report of Possible observation of Graphene Oxide by optic and electronic microscopy in a vial of Comirnaty product (official now with picture of the original vial).

(PDF) DETECCIÓN DE OXIDO DE GRAFENO �EN SUSPENSIÓN ACUOSA (COMIRNATYTM (RD1)��ESTUDIO OBSERVACIONAL EN MICROSCOPIA ÓPTICA Y ELECTRÓNICA�Informe provisional (I)

PDF | AVISO IMPORTANTE Seguidamente se presenta un estudio microscópico, observacional y meramente descriptivo de una muestra problema de vacuna... | Find,…

www.researchgate.net

(PDF) DETECCIÓN DE OXIDO DE GRAFENO �EN SUSPENSIÓN ACUOSA (COMIRNATYTM (RD1)��ESTUDIO OBSERVACIONAL EN MICROSCOPIA ÓPTICA Y ELECTRÓNICA�Informe provisional (I)�ANEXO FOTOGRAFIAS

PDF | DETECCIÓN DE OXIDO DE GRAFENO �EN SUSPENSIÓN ACUOSA (COMIRNATYTM (RD1)��ESTUDIO OBSERVACIONAL EN MICROSCOPIA ÓPTICA Y ELECTRÓNICA�Informe... | Find, read…

www.researchgate.net

Technical report of confirmation of presence of Graphene Oxide in vials of all 4 major brands of Covid vaccines by micro-Raman spectroscopy. (Authorized English translation from Spanish)

(PDF) DETECTION OF GRAPHENE IN COVID19 VACCINES

PDF | We present here our research on the presence of graphene in covid vaccines. We have carried out a random screening of graphene-like nanoparticles... |…

www.researchgate.net

Technical report of observation of diverse microscopic objects, including potential microbiota , in sample vials of all brands of Covid vaccines. (Authorized English Translation from Spanish).

(PDF) MICROSCOPIC OBJECTS FREQUENTLY OBSERVED IN mRNA COVID19 VACCINES

PDF | Here we show some of the more common objects that could be observed in sealed vials from different random samples of COVID19 mRNA vaccines through... |…

www.researchgate.net

English subtitled presentation of the micro Raman spectroscopy results by Dr. Pablo Campra.

Technical report on the detection of graphene oxide in COVID vaccines

More information: https://www.orwell.city/2021/11/special-program.html Dr. Pablo Campra, Ph.D. in Chemical Sciences and graduate in Biology, explains the…

rumble.com

English Subtitled translation of interview to Dr. Pablo Campra in Spanish open TV Channel El Toro TV.

Dr. Pablo Campra in Vivir con Salud (El Toro TV)

More information: https://www.orwell.city/2021/11/vivir-con-salud.html Dr. Pablo Campra gives details on the technical report he published on the detection of…

rumble.com

Quote from JedRothwell

Last year there were no vaccines! What you are saying is ridiculous. What will you say when this does not happen? I predict you will pretend you never said it.

Unless another new variant comes along, the pandemic is over in Japan, and Argentina, Israel, and every other country with a functional public health system and sane citizens. It will continue to kill hundreds of thousands of lunatics who refuse to be vaccinated.

Said the man who I quote, if you get vaccinated you will not get Covid, will not spread Covid, will not have symptoms, or will not die. All false!!!

The Original Antigenic Sin: COVID-19 Vaccination and Sub-Optimal Initial Immune Priming Deranges the Antibody- Cytotoxic T cell Immune Response

The Original Antigenic Sin: COVID-19 Vaccination and Sub-Optimal Initial Immune Priming Deranges the Antibody- Cytotoxic T cell Immune Response

Note that views expressed in this opinion article are the writer’s personal views and not necessarily those of TrialSite. Free to read and Share without

trialsitenews.com

By Paul Elias Alexander, PhD, Mark Trozzi, MD, Dan Stock, MD

Drs. Vanden Bossche and Montagnier have warned us about vaccinating during a pandemic with heavy infectious pressure and the use of very narrow spike specific (an immature, sub-optimal, incomplete, immune library spectrum) yielding, sub-optimal antibodies. That we could possibly drive vaccine-mediated viral immune escape and I argue we are seeing just that now in the UK and Israel and even in the US. “It is clear that the new variants are created by antibody-mediated selection due to the vaccination.” It is the vaccination and sub-optimal incomplete ‘unhinged and deranged’ antibody responses that is driving the emergence of the variants. Is this why so many young healthy athletes are dying?

It is now abundantly clear that the COVID-19 vaccines are ‘leaky’ (leaky vaccines do not stop infection or transmission and allows for immune escape) and do not sterilize the COVID virus (are non-neutralizing or lose this capacity very quickly). These vaccines show that the more vaccinated a nation is, the more problems they are having with the vaccine in terms of escalating infections. These vaccines do not adequately protect the upper respiratory tract. The data is clear that the vaccinated can transmit as efficiently as some who are completely unprotected. Immunity from the vaccines seem to be only about 4 to 5 months and thus how could any one think we can achieve population level herd immunity with these vaccines? It is virtually impossible that these vaccines could get us to herd immunity. Zero chance. Yet are we about to accept boosting every 5 months? Do we know if the immune system is designed for this? This, as well as antibody dependent enhancement (ADE) and antibody mediated viral enhancement (AMVE) were not studied. This was a catastrophic omission and failure by the vaccine developers and the FDA as the key regulator in enforcing this.

Yet why would the CDC, NIH, and vaccine developers and their supporters continue to push these leaky ‘imperfect’ vaccines onto the population, especially low-risk persons when the antibody immunity quickly wanes and all you are doing is setting the population up for repeated boosters that carry risk itself? Why did vaccine developers bring these imperfect vaccines, as if it were set to fail from inception? As mentioned, we have not studied if the human immune system is capable of withstanding repeat vaccine boosting. We are seeing that the vaccinated are at some point, driving transmission with a vaccine that has limited ‘questionable’ immunity.

Our thesis is that the double-vaccinated and triple-vaccinated (likely quadruple vaccinated in Israel) are (would) driving the transmission of the Delta variant with severe consequences for the vulnerable unvaccinated (and vaccinated). They are functioning potentially as asymptomatic super spreaders. That these COVID vaccines are functioning to keep the vaccinated person alive but allowing for infection and transmission which could permit very virulent strains to circulate within a population. What we are seeing at present cannot really be explained by differences in variants and this breakdown in infections among vaccinated persons. People who are double vaccinated are being made to shed virus at alarmingly high levels.

The Marek’s disease/Read et al. (‘leaky’ non-sterilizing, non-neutralizing imperfect vaccines that reduce symptoms but do not stop infection or transmission) in chickens model and the concept of the Original antigenic sin (the initial priming of the immune system or exposure prejudices the immune response life-long to that pathogen/virus or similar, and if the initial priming of the immune system is indeed sub-optimal, then the subsequent response (exposure) may be sub-optimal to that pathogen or similar/related ones) may explain what we are potentially facing now with these imperfect COVID vaccines (which is immune escape, increased viral load, increased transmission, faster transmission, and potentially more ‘hotter’ variants). I wish to make the case that we may be able to explain the surging infections (hospitalization and death) in vaccinated persons as well as unvaccinated persons via the concept of the Original antigenic sin. While some may argue that it is a theoretical argument, the data I am seeing could well be explained by this. I see no other explanation at this time for what we are seeing in the data post vaccine in UK, Israel, US etc.

Penn State’s Ohm similarly writes “Leaky vaccines work…without necessarily blocking or slowing viral replication. The result is that infected but vaccinated individuals have extended survival, allowing highly virulent pathogen that would normally reach an evolutionary dead-end in a dead host, that can transmit.” Boots echoed similar and again we suggest that we are possibly facing a Marek 2.0 now with these clearly imperfect COVID vaccines. Yes, more data and acute definitive research is needed for this was not studied by the vaccine developers and we are in the dark as to how these vaccines behave medium and long-term as to safety. We are in a black box situation. However, what is shaping up raises many urgent questions and is potentially ominous. We run the risk of killing many with these vaccines, and particularly our children if what we are seeing is the tip of ADE/AMVE.

We are actually seeing major COVID hospitalizations, ICU admissions, and deaths in the UK among the fully vaccinated. This is a huge problem and this may be an AMVE/ADE that we feared. A virologist’s worst nightmare. An enhancing antibody need not be present (Dr. Dan Stock, personal communication, November 8th 2021) and this nuance must be factored into our discussion. “The greatest deficit is that caused by Th 2 shifting away from CD 8+ cytotoxic natural killer cellular response to the local infection, which is necessarily induced, regardless of what type of Ab gets produced…unhelpful antibodies really are not required for the immune system derangement.”

We argue that it may well be that enough corners were cut in the vaccine trials and manufacture under Operation Warp Speed (OWS) to reduce the timelines, resulting in sub-optimal harmful vaccines being brought to the society. Was the prior President Trump mislead and misinformed by his scientific advisors and vaccine developers? I argue they did mislead him. Had the studies been conducted properly as to the vaccine safety aspects and for the proper durations, had we followed up long enough to examine AMVE/ADE, then it is likely that we would not be witnessing what is unfolding in UK’s data and Israeli data today. Or the US with clear vaccine failure and the potentially dangerous need for repeat boosting. Repeat boosting could be devastating.

We write here because of our fear of what will possibly happen to our children if we proceed to mass vaccinate healthy children. We think based on what has materialized thus far, that we could seriously hurt many children with these vaccines. Importantly, children just do not have significant risk from this virus and must be left alone. This vaccine is not needed and the government public health leaders (Francis Collins/NIH, Anthony Fauci/NIAID, and Rochelle Walensky/CDC nor the FDA/Woodcock and Marks) or vaccine developers have not prosecuted their case as to why children need these vaccines. Moreover, we run the risk of turning children into asymptomatic super spreaders (as is happening in adults now in UK and Israel (and US)) as well as incurring lethal outcomes, if we move forward with mass vaccination.

Where is the evidence that underpins this thesis that we are indeed staring down the barrel of Marek 2.0? The recent Public Health England (PHE) reports # 44 and # 45 are a key aspect of this thesis (as are 5 prior PHE reports) and while speculative and theoretical, we think these reports raise serious issues that we cannot discount. We even think we are past theoretical. We unfold the discussion with the following studies that set the table by revealing the failure and immense challenges with the current vaccines (particularly Pfizer) with regard to the Delta variant.

The vaccine has clearly failed against Delta and the fully vaccinated are revealing staggering infection and propensity to transmit. For example, we have present research findings by Singanayagam et al. (fully vaccinated individuals with breakthrough infections have peak viral load similar to unvaccinated cases and can efficiently transmit infection in household settings, including to fully vaccinated contacts), by Chau et al. (viral loads of breakthrough Delta variant infection cases in vaccinated nurses were 251 times higher than those of cases infected with prior strains early 2020), and by Riemersma et al. (no difference in viral loads when comparing unvaccinated individuals to those who have vaccine “breakthrough” infections and if vaccinated individuals become infected with the delta variant, they may be sources of SARS-CoV-2 transmission to others) that reveal the vaccines have very sub-optimal efficacy. This troubling situation of the vaccinated being highly infectious and transmitting the virus has also clearly emerged in seminal nosocomial outbreak papers by Chau et al. (HCWs in Vietnam), the Finland hospital outbreak (spread among HCWs and patients), and the Israel hospital outbreak (spread among HCWs and patients). These studies also troublingly revealed that the PPE and masking were essentially ineffective within the healthcare setting. All of the HCWs were double vaccinated yet there was extensive spread to themselves and their patients.

In addition, Nordström et al. (vaccine effectiveness of Pfizer against infection waned progressively from 92% day 15-30 to 47% day 121-180, and from day 211 and onwards no effectiveness), Suthar et al. (a substantial waning of antibody responses and T cell immunity to SARS-CoV-2 and its variants, at 6 months following the second immunization), Yahi et al. (with delta variant, neutralizing antibodies have a decreased affinity for the spike protein, whereas facilitating antibodies display a strikingly increased affinity), Juthani et al. (higher numbers of patients with severe or critical illness in those who received the Pfizer vaccine), Gazit et al. (SARS-CoV-2-naïve vaccinees had a 13-fold increased risk for breakthrough infection with the Delta variant, and substantially elevated risk of symptomatic COVID and hospitalization), and Acharya et al. (no significant difference in cycle threshold values between vaccinated and unvaccinated, asymptomatic and symptomatic groups infected with Delta) collectively reveal the poor efficacy and even negative efficacy of the COVID vaccines. Levine-Tiefenbrun et al. reports that the viral load reduction effectiveness declines with time after vaccination, “significantly decreasing at 3 months after vaccination and effectively vanishing after about 6 months.”

As an example, the Swedish study (retrospective with 842,974 pairs (N=1,684,958)) is particularly alarming for it shows that while the vaccine provides temporary protection against infection, the efficacy declines below zero and then to negative efficacy territory at approximately 7 months, underscoring that the vaccinated are highly susceptible to infection and eventually become highly infected (more so than the unvaccinated). A further example emerges from Ireland whereby reporting suggests that Waterford city district has State’s highest rate of Covid-19 infections, while the county also boasts highest rate of vaccination in the Republic (99.7% vaccinated). Reports are that the U.S. Covid-19 deaths for 2021 surpassed the deaths from 2020, leading some to state that “more people have died from COVID-19 in 2021, with most adults vaccinated and nearly all seniors), than in 2020 when nobody was vaccinated”.

So the evidence has accumulated (as above) that there is breakthrough and the vaccine is failing against the Delta variant. There is no question. Even CDC’s Director Rochelle Walensky admitted that the vaccines are not stopping transmission which is an admission of a failed vaccine. Again, the Marek’s disease in chickens and the vaccination situation explains what we are potentially facing with these leaky vaccines (increased transmission, faster transmission, and more ‘hotter’ variants).

One model of AMVE/ADE surrounds the Original antigenic sin and the initial priming of the immune system or exposure prejudicing the immune response life-long to that pathogen/virus or similar. Moreover, if the initial priming of the immune system is indeed sub-optimal, then the subsequent response (exposure) may be sub-optimal to that pathogen or similar/related ones.

I am no virologist or immunologist as I seek to make sense of the data we are seeing and what is happening to vaccinated and unvaccinated persons. I am guided by the tremendous work of Dr. Dan Stock and my explanation post vaccination (with his expert input) is as follows:

If the initial priming/exposure is via vaccine, then the helper T-cell (CD 4+) immune response would be biased (switched) toward a Th 2 B-cell and antibody response and a more limited Th1 CD 8+ cytotoxic T cell response at the localized native site of infection. The immune system is forced to choose between Th 1 and Th2 differentiation, and that such differentiation is permanent. It is ‘learning’ that anytime you are exposed to the virus in the wild (or similar virus), that it should switch to the Th 2 pathway and make less Th 1 cytotoxic immunity because you have taken the vaccine. The immune system is forced to switch between Th 1 and Th 2 immune responding pathways and if it does respond systemically with antibodies (if your first exposure is vaccine), then when you are indeed infected in the future with the virus as a localized respiratory tract infection (your immune system’s second look at the virus), your immune system would be responding wrong (disturbed) and not with the cytotoxic CD 8+ response that is actually (optimally) needed at the site of infection (respiratory tract). In other words, the signals sent by the local tissue to the immune system says to produce B cells and antibodies and not the needed cytotoxic cells at the local site of infection to begin clearing out the infection.

The result is that the respiratory tissue (lungs) become more infected (as the cytotoxic cells are not there or not enough of it is produced to clear the infection) and sicker and sicker and the infected person could be very infected with more and more virus as the CD 8+ response is diminished or maybe non-existent. The vaccinated person would be then potentially become very ill and at the same time, amassing massive viral load and capable of transmitting virus. So the infection is building up in the local tissues (the primary site of infection) and not being cleared by the cytotoxic response which has been tamped down. This may help explain the data we are seeing out of UK (reports # 44 & 45 and reports 39-43) with deaths not only in the vulnerable unvaccinated but in the vaccinated. This is a real problem if this is indeed what is occurring. A systemic presentation (due to the vaccine) must necessarily reduce Th 1 response as it drives Th 2 response, allowing not only increased shedding, but eventually driving a pathogen that would naturally not rapidly disseminate, and certainly not before it was eradicated, into an uncheckable pathogen that would more rapidly and dependably disseminate, further driving progressive Th 2 differentiation, reduced Th 1 response, until eventually the infection would not have any meaningful Th 1 response. The result is the lungs are destroyed and the upper limit of Th 2 response is reached. Then we would see not only spread to the naive unvaccinated, but increased death in the vaccinated, who would never recover with proper immune response as the immune system ‘learns’ the initial sub-optimal incorrect response (away from CD 8+ cytotoxic responding) and responds in that direction with subsequent exposure/boosting. Boosting will be devastating for it will only drive this deranged immune response and it will build and the vaccinated will get sicker and sicker for there is no Th 1 cytotoxic response available. The immune system effectively learns to respond incorrectly and the result is the tissue in the respiratory tract/lungs getting more and more infected and sicker, and the vaccinated person at risk of severe illness as the vulnerable vaccinated is also at risk of infection and severe outcome. Even if the nearby unvaccinated has a robust immune system, it could be overwhelmed with virus from the vaccinated person who is shedding and churning out massive infection (as the CD 8+ pathways is stepped down). Both can become very ill and die.

So when we look more closely at the Public Health England (PHE) report # 44 & 45 (including reports # 39 to 43) which has very granular data, we see that the infections are markedly higher in those vaccinated in all age groups over 30 (tables 2-5), the shift to those 30 years and above occurring between week 35 and week 38 in the report # 39. Table 5 while reporting unadjusted data, is very instructive as to the most current rates between week 40 and week 43 2021 (page 20 in report # 44) (Table 1 & 2), and note week 44 data is reported as ‘unadjusted’. The same emerges in report # 45 (Table 6 page 22, between week 41 and week 44 2021). We see a stable and consistent trend in this robustly collected and reported UK data in that the vaccinated (it appears) are becoming more highly infected with the Delta variant and the unvaccinated are being hospitalized and dying (along with the vaccinated). The unvaccinated are a particular concern given their vulnerability and these alarming rates. A recent Yahoo UK report is sounding alarm as are others where we are witnessing the highest rates of infection, hospitalization, and death in nations most vaccinated. There are similar reports in Scotland that the fully vaccinated accounted for “89% of Covid-19 deaths in the past four weeks, whilst also accounting for 77% of Covid-19 hospitalisations and 65% of alleged Covid-19 cases from October 9th through to November 5th.”

Conclusion

Is the COVID vaccine protecting us from serious damage but not preventing us from getting the virus, and as such (as seen in the UK data) driving more lethal variants? Are we really looking at imperfect vaccination that is keeping us alive but allows transmission, not the killing of the virus, so that the vaccinated are transmitting the virus and actually more potent virus? That the vaccinated themselves are becoming very ill given a deranged immune response. As seen in the vaccination against Marek’s disease in chickens, we may be witnessing that vaccination against COVID-19 virus and disease is favouring higher virulence (to vaccinated and vulnerable unvaccinated).

From where we sit, we argue that this is not a theoretical risk anymore and the data we are looking at suggests this is actually what we are witnessing now in Israel, UK, etc. I see no other data that could explain what we are witnessing and this deranged incorrect immune response between switch Th 1 to Th 2 immune responding seems to be the best explanation thus far. How do we address this as this is potentially catastrophic? We argue to stop the vaccination (with focus on high-risk persons if properly informed and consented; we offer, or make available the vaccine, but we do not mandate) and the reality is that if this model bears out, then boosting will further derange the immune system that is biased toward an antibody response when a needed cytotoxic immune response on subsequent exposures, is not there or severely set aside. We also say, under no condition, none, do we allow our low-risk healthy children to be vaccinated with these sub-optimal, imperfect, leaky and largely safety untested vaccines that only provides a potential opportunity for harm. Our view is we impose a hard stop now on these vaccines/boosters. We must ask the vaccine developers to address the harms we are seeing before moving further and in fact, we have many alternatives to address this emergency. We do not need these vaccines. We never did. It is imperative to consider alternatives beyond just vaccinating e.g. using non-vaccine disease prevention, such as early outpatient treatment and available nutraceuticals such as with Vitamin D/calcifediol, Zinc, and prophylactic ivermectin

AstraZeneca's antibody drug over 80% effective at preventing Covid, trial shows

AstraZeneca's antibody drug over 80% effective at preventing Covid, trial shows

AstraZeneca's antibody treatment has been shown to be highly effective at preventing Covid in people who may not respond well to vaccines.

www.cnbc.com

AstraZeneca's antibody treatment has been shown to be highly effective at preventing Covid-19 in people who may not respond well to vaccines, according to new clinical trial results.

The results showed that patients given a single injection of the antibody treatment, known as AZD7442, were 83% less likely to develop symptomatic cases of the coronavirus than participants who were given a placebo

An earlier analysis of the trial, conducted three months after the treatment was administered, had shown that the risk of developing severe disease was reduced by 77%.

Six months on from the treatment being administered, no severe cases of Covid-19 or deaths from the virus had been recorded among patients given the antibody cocktail. In a group given the placebo, five participants contracted severe Covid-19 within six months of the trial beginning, and there were two Covid-related deaths.

More than 75% of participants in the trial had underlying conditions that put them at high risk of contracting severe Covid-19, including those whose immune systems were compromised and therefore may have a reduced response to vaccination

Around 2% of the world's population is thought to be at risk of not responding well to Covid-19 vaccines, according to AstraZeneca. This includes people receiving dialysis treatment, undergoing chemotherapy, and those taking immunosuppressive drugs for conditions like rheumatoid arthritis.

The phase three clinical trial was conducted across 87 sites in five countries: the U.S., the U.K., Spain, Belgium and France. A total of 5,197 people took part, with 3,460 receiving 300mg of AZD7442 and 1,737 being given a saline placebo

The six-month assessment included data from 4,991 of the participants, with those who chose to leave the trial to get vaccinated being excluded from the data analysis. Subjects will continue to be assessed for 15 months.

'Compelling results'

In a separate trial, patients with mild-to-moderate Covid-19 who were given one dose of AZD7442 within three days of developing symptoms had their risk of developing severe disease reduced by 88%.

Half of this trial's 903 participants were given 600mg of AZD7442, while the other half were given a placebo.

Ninety percent of those included in the second study were considered to be at high risk of developing severe Covid-19 if they contracted the virus.

The trial's full results have not yet been peer reviewed, but are set be submitted for publication in a peer reviewed medical journal.

AstraZeneca said both trials showed that AZD7442 was "generally well tolerated."

"These compelling results give me confidence that this long-acting antibody combination can provide my vulnerable patients with the long-lasting protection they urgently need to finally return to their everyday lives," Hugh Montgomery, professor of intensive care medicine at University College London and principal investigator in the trials, said in a press release Thursday

AZD7442 reduced risk of developing severe COVID-19 or death in TACKLE Phase III outpatient treatment trial

Quote from THHuxleynew

Stats 101: correlation <> causation

I didn't expect anything different from you Thomas, you are so predictable. Thanks but on nvitamin D you are wrong and 40 years of studies show you are wrong. Higher levels of vitamin D leads to less mortality in all disease, and I have posted all the studies that show that. Supplementation of vitamin D might have saved millions and yes Thomas it looks like it's that simple. Go back and read the studies!!!

Quote from stefan

He drives the thesis that ivermectin do have good properties for covid, but not by directly attacking covid, but in stead suggest that people with both covid and worms is better off without the worms as ivermectin is a known worm killer, which is a theory I kind of like for it's logical soundness and explain why many intelligent persons have though that there was evidences for ivermectin.

Stefan as I know that you are an intelligent person I wonder that you can defend such shit ideas. Ivermectin has shown 100% effective in prophylaxis in real live not by killing worms. One sample::2 large care home on scabies cure had no CoV-19 infections where all personal got it!!! Care home = all age >80 most severe risk group!

This person simply is a big pharma paid agent to divert people away from the best existing cure.

Quote from Wyttenbach

Stefan as I know that you are an intelligent person I wonder that you can defend such shit ideas. Ivermectin has shown 100% effective in prophylaxis in real live not by killing worms. One sample::2 large care home on scabies cure had no CoV-19 infections where all personal got it!!! Care home = all age >80 most severe risk group!

This person simply is a big pharma paid agent to divert people away from the best existing cure.

I would argue that we all here are intelligent as we avoid spending all time watching TV, and in stead do something creative like discuss stuff. My TV is collecting dust, and when I see movies I tend to go to the cinema. Last time Dune witch I can recommend and I also liked the book.

Stefan, I'm curious : In Sweden are the unvaccinated allowed in movie theatres?

In Toronto, definitely not.

Some things I've heard recently : In Austria, as we know, the unvaccinated are locked down and are not allowed to go outside except for essential activities like work and grocery shopping. Strolling in a park is not essential. Police are out to occasionally ask people for their 'papers'.

In France, if you're 65 and older, starting in mid December if you've not had the booster, your vaccine passport will go from green to red, and no more visiting the cafe for you!

Quote from Mark U

In Austria, as we know, the unvaccinated are locked down and are not allowed to go outside except for essential activities like work and grocery shopping.

There are plans for a general lockdown for all (vaxx/unvaxx/recovered) in parts, probably even all of Austria from next week on due to record incidences around 1600, and growing...

Quote from Mark U

Stefan, I'm curious : In Sweden are the unvaccinated allowed in movie theatres?

In Toronto, definitely not.

Some things I've heard recently : In Austria, as we know, the unvaccinated are locked down and are not allowed to go outside except for essential activities like work and grocery shopping. Strolling in a park is not essential. Police are out to occasionally ask people for their 'papers'.

In France, if you're 65 and older, starting in mid December if you've not had the booster, your vaccine passport will go from green to red, and no more visiting the cafe for you!

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Things are becoming bad but not too bad atm, because probably because of political pressure from the conservative opposition (the FHM has been criticized of moving too

slow). ATM if there are 100 persons or more you need either a vaccine pass to arrange for example a sports event or make sure people are not too crowded. Probably this mean that an unvaccinated will not be able to attend some stuff If numbers go bad. Also they will essentially reduce the count limit if infection numbers go up, there are also more social distancing recommendation in preparations like work from home and they started testing all again. They expect that we will catch up to Europe soon as they can't find any reasons why we would not do it. Currently the ICU situations is pretty calm. September showed that most people in ICU was unvaccinated, but that's for low levels of total cases and lot's of people are just a few months from the most active age groups having the shot, which works well short term it seam. We have members in the family that has not taken all shot, but in stead have gotten COVID itself. We are trying to understand if we need to stupidly isolate because of this. There is nothing that specify that you need booster shots. After winter comes the summer and I like reading a good book or poke with computers and math, so personally I am not specially depressed about the vaccine pass stuff.

Here in Toronto, 85 percent of people 12 and older have apparently been double vaccinated. That is very high, especially for a very ethnically mixed population. My street though seems to be an outlier. Out of the 8 neighbours (from 8 different houses) I have talked to over the last few months, 5 are still unvaccinated, as are the people in their households. Interestingly, 3 of the 5 households are people of Polish heritage. Polish people have been messed with by the left and the right, by communists and nazi's, and perhaps they are on alert as to how readily society can fall under totalitarianism.

A few days ago I bumped into a couple in their early 70s (it seems), who are originally from England. We see each other and briefly chat at least once a month, as we are out walking our dogs. I vaguely recall about a month ago, they asked me if I was vaccinated yet, and I casually said I wasn't. Well a few days ago I saw them across the street, and when my dog crossed the road to greet their dog, the man asked me right away if I had been vaccinated. When I said no, it's not for me, he said, and I quote, You're an enemy of the state. After I asked him if he was joking, he managed to repeat it a few more times. No, he wasn't joking. He now had a grim countenance (yet strangely his wife was smiling like nothing was wrong). My how things have changed. In our city it is get-vaccinated non stop propaganda from every direction. I suppose it shouldn't be a surprise that some otherwise normal people are now fear-filled and a bit ... unhinged.

Estimating dose-response relationships for vitamin D with coronary heart disease, stroke, and all-cause mortality: observational and Mendelian randomisation analyses

DEFINE_ME

Summary

Background

Randomised trials of vitamin D supplementation for cardiovascular disease and all-cause mortality have generally reported null findings. However, generalisability of results to individuals with low vitamin D status is unclear. We aimed to characterise dose-response relationships between 25-hydroxyvitamin D (25[OH]D) concentrations and risk of coronary heart disease, stroke, and all-cause mortality in observational and Mendelian randomisation frameworks.

Methods

Observational analyses were undertaken using data from 33 prospective studies comprising 500 962 individuals with no known history of coronary heart disease or stroke at baseline. Mendelian randomisation analyses were performed in four population-based cohort studies (UK Biobank, EPIC-CVD, and two Copenhagen population-based studies) comprising 386 406 middle-aged individuals of European ancestries, including 33 546 people who developed coronary heart disease, 18 166 people who had a stroke, and 27 885 people who died. Primary outcomes were coronary heart disease, defined as fatal ischaemic heart disease (International Classification of Diseases 10th revision code I20-I25) or non-fatal myocardial infarction (I21-I23); stroke, defined as any cerebrovascular disease (I60-I69); and all-cause mortality.

Findings

Observational analyses suggested inverse associations between incident coronary heart disease, stroke, and all-cause mortality outcomes with 25(OH)D concentration at low 25(OH)D concentrations. In population-wide genetic analyses, there were no associations of genetically-predicted 25(OH)D with coronary heart disease, stroke, or all-cause mortality. However, for the participants with vitamin D deficiency (25[OH]D concentration <25 nmol/L), genetic analyses provided strong evidence for an inverse association with all-cause mortality (odds ratio [OR] per 10 nmol/L increase in genetically-predicted 25[OH]D concentration 0·69 [95% CI 0·59–0·80]; p<0·0001) and non-significant inverse associations for stroke (0·85 [0·70–1·02], p=0·09) and coronary heart disease (0·89 [0·76–1·04]; p=0·14). A finer stratification of participants found inverse associations between genetically-predicted 25(OH)D concentrations and all-cause mortality up to around 40 nmol/L.

Interpretation

Stratified Mendelian randomisation analyses suggest a causal relationship between 25(OH)D concentrations and mortality for individuals with low vitamin D status. Our findings have implications for the design of vitamin D supplementation trials, and potential disease prevention strategies.

Funding

British Heart Foundation, Medical Research Council, National Institute for Health Research, Health Data Research UK, Cancer Research UK, and International Agency for Research on Cancer.

Quote from Mark U

Here in Toronto, 85 percent of people 12 and older have apparently been double vaccinated. That is very high, especially for a very ethnically mixed population. My street though seems to be an outlier. Out of the 8 neighbours (from 8 different houses) I have talked to over the last few months, 5 are still unvaccinated, as are the people in their households. Interestingly, 3 of the 5 households are people of Polish heritage. Polish people have been messed with by the left and the right, by communists and nazi's, and perhaps they are on alert as to how readily society can fall under totalitarianism.

A few days ago I bumped into a couple in their early 70s (it seems), who are originally from England. We see each other and briefly chat at least once a month, as we are out walking our dogs. I vaguely recall about a month ago, they asked me if I was vaccinated yet, and I casually said I wasn't. Well a few days ago I saw them across the street, and when my dog crossed the road to greet their dog, the man asked me right away if I had been vaccinated. When I said no, it's not for me, he said, and I quote, You're an enemy of the state. After I asked him if he was joking, he managed to repeat it a few more times. No, he wasn't joking. He now had a grim countenance (yet strangely his wife was smiling like nothing was wrong). My how things have changed. In our city it is get-vaccinated non stop propaganda from every direction. I suppose it shouldn't be a surprise that some otherwise normal people are now fear-filled and a bit ... unhinged.

Awful, people should be a bit more relaxed. 80% of people over 16 is vaccinated here as well, there is some social pressure to vaccinate, but people are relaxed about it and the tone here is not as bad as you describe, at least in my social group and in media. It's more like people try to convince you with facts than try to bang it into your head. We have actually more aggressiveness from the anti vaccination crowed here.

Quote from Nar

As Japan is starting to open up its border more (e.g. allowing business and student visa arrivals) it is reasonably inevitable IMO that there will be a rise in cases.

That is unlikely. They rigorously test everyone who comes in, and they quarantine everyone for a week. They find ~5 infected people a day coming in. Even if there were 100 a day, I doubt many would come it without being detected. See the "port of entry" category at the bottom of this page:

Japan COVID-19 Coronavirus Tracker

Live updates of the Coronavirus COVID-19 outbreak in Japan

covid19japan.com

In the whole country, there are presently 160 new cases per day, and 5 or 10 deaths. That is a minor problem in a country with 120 million people. Their hospitals and case tracking resources can easily contain that.

If a new variant emerges that the vaccines cannot contain, that will be a different story.

Nationwide Australian Study: Serious Long-Term Impacts of COVID-19

Nationwide Australian Study: Serious Long-Term Impacts of COVID-19

A group of researchers in Australia concluded a study probing into the impacts of being critically ill with COVID-19 over time. Led by Carol L. Hodgson

trialsitenews.com

A group of researchers in Australia concluded a study probing into the impacts of being critically ill with COVID-19 over time. Led by Carol L. Hodgson with Monash University School of Public Health and Preventive Medicine, the study team reports that after six months from initial COVID-19 illness recovery, one in five (20%) had died while nearly 40% of those studied disclosed a new disability. Published in Critical Care, the study titled, ”The impact of COVID-19 critical illness on disability, functional outcomes and return to work at 6 months: a prospective cohort study” was embedded in the Australian nation-wide SPRINT-SARI observational prospective cohort study involving 30 ICUs.

Based in Australia, the researchers, including members of the COVID-19 Recovery Study Investigators and the ANZICS Clinical Trials Group–embedded in a larger Short Period Incidence Study of Severe Acute Respiratory Infection (SPRINT-SARI) observed some long-term consequences associated with critical COVID-19 illness.

An important study, few studies to date, had systematically investigated the actual ongoing impacts of COVID-19 from six months after recovery, including any new functional impairments. Specifically, the Australia-based investigators observed the incidence of death, new disability, or related functional impairment as well as any changes in health-related quality of life for people who have previously been critically ill with COVID-19.

The Study

This nationwide, multicenter registry—embedded prospective cohort study (NCT04401254) was conducted at 30 intensive care units (ICUs) across Australia. Importantly, the study team secured ethical approval at all participating sites as well as a waiver of consent for hospital data while including an opt-out consent for follow up post 6 months recovery.

The investigational team sought to identify any specific predictors of disability-free survival. As referenced previously, this study was embedded in the larger SPRINT-SARI study, thus offering the investigators access to patient data in 30 ICUs. In fact, this larger study included 95% of all ICU COVID-19 admissions in Australia. Vital national data, the same underlying data were used for the Australian Government’s ICU COVID-19 patient reports.

The study commenced with 274 patients enrolled in SPRING-SARI while a total of 212 participated in this specific study. The ultimate follow up cohort totaled 160 of the patients. The flow chart from the Critical Care entry demonstrates the study participant numbers.

SPRINT-SARI Patients

The impact of COVID-19 critical illness on new disability, functional outcomes and return to work at 6 months: a prospective cohort study

The impact of COVID-19 critical illness on new disability, functional outcomes and return to work at 6 months: a prospective cohort study - Critical Care

Background There are few reports of new functional impairment following critical illness from COVID-19. We aimed to describe the incidence of death or new…

ccforum.biomedcentral.com

Quote from Mark U

You're an enemy of the state. After I asked him if he was joking, he managed to repeat it a few more times.

6 months needed to turn Canada in a fascist (Nazi) country. Same words as in Germany post 1932...

Quote from Fm1

A group of researchers in Australia concluded a study probing into the impacts of being critically ill with COVID-19 over time.

Hit a cat with hammer and study what happens. Auschwitz II. AUS has forbidden to prescribe treatment drugs for COV-19. An other Nazi concentration camp!

Quote from Wyttenbach

Hit a cat with hammer and study what happens. Auschwitz II. AUS has forbidden to prescribe treatment drugs for COV-19. An other Nazi concentration camp!

Here's a Trial Site News video, where Dr. Nikolai Petrovsky of Australia is interviewed. He and his company have invented a new protein based Covid vaccine which is now approved in Iran and is sought for approval in Australia. He describes how it is illegal in Australia for a doctor to publicly compare vaccines, and illegal for a doctor to prescribe, let alone publicly mention, drugs like Ivermectin. You will get your medical registration cancelled, your medical license removed. So, all medical doctors in Australia are under a gag order. Two minutes from 36:45 to 38:45

New Zealand Study: High-Fiber Diet Improves COVID-19 Vaccine Immune Response

New Zealand Study: High-Fiber Diet Improves COVID-19 Vaccine Immune Response

A study from the Malaghan Institute of Medical Research has found that a high fiber diet can improve the immune response to the first dose of a

trialsitenews.com

A study from the Malaghan Institute of Medical Research has found that a high fiber diet can improve the immune response to the first dose of a vaccine. Published in Frontiers in Immunology, the finding has implications for how we might tailor our diets to stimulate the best protective effect from novel vaccines.

The study, funded by High Value Nutrition Ko Ngā Kai Whai Painga National Science Challenge, investigated immune responses to the influenza vaccine. Participants were asked to report on their diets, with samples of their gut microbiome tested to understand which types of bacteria were prevalent prior to vaccination. After being given the influenza vaccine, participants’ blood was then analysed to assess the resulting antibodies they produced and determine how responsive their immune system was to the vaccine.

Fiber-Rich Diet Important

“Initially, our goal was to see if there were any specific types of bacteria that could predict the immune response to the vaccine,” says the Malaghan Institute’s Dr Alissa Cait. “Interestingly, we found that for participants who were receiving their influenza vaccine for the first time, those who had the best immune responses had a prevalence of fibre-specific bacteria in their gut.”

Our bodies need gut bacteria to fully digest our food, and our gut microbiome is often a reflection of our diet. Many fiber-specific bacteria indicate those participants ate a diet high in fiber.

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“These results suggest that those who consume a diet rich in fiber from foods such as fruits, vegetables and grains seem to produce a better immune response to the first dose of a vaccine due to specific colonies of bacteria that are cultivated in their guts,” says Dr Cait.

As well as helping us digest our food, the by-products of these bacteria fermenting fibre are molecules called short-chain fatty acids. It’s these molecules, not the fibre on its own, that have been shown to influence our immune response.

“Our bodies actively transport short chain fatty acids from our gut to our blood system where they circulate around the body,” says Dr Cait. “Our previous research has shown that these molecules appear to have a balancing effect on our immune system – dampening allergic and autoimmune responses while stimulating immune responses towards invasive organisms like viruses or bacteria – and vaccines.”

Results

The results from the study indicate that diet is most influential when a person is receiving the first ever dose of a vaccine. For subsequent vaccinations for the same disease (like the seasonal flu jab), factors such as the immune memory seem to have a greater impact on the resulting immune response.

For people receiving their first dose of the COVID-19 vaccination, Dr Cait suggests that slight alterations to diet to include more fibre may have additional protective benefits.

“These results suggest that we can develop strategies to improve the protection we get from vaccines simply by eating a more balanced diet.” says Dr Cait. “It’s the age-old advice, eat a balanced diet and reap a multitude of health benefits. Now we can potentially add improved vaccine protection to this long list.”

Ongoing Study

As part of Vaccine Alliance Aotearoa New Zealand’s Ka Mātau, Ka Ora clinical study into COVID-19 vaccine immune responses in New Zealanders, Dr Cait and her team are now investigating if the amount of dietary fiber participants consume is influencing the number of antibodies participants produce after receiving the Pfizer-BioNTech vaccine. They hope this will provide more insight into how we can practically optimise our diets to achieve more protection from vaccines developed in the future.

About the Malaghan Institute of Medical Research

An independent biomedical research institute based in Wellington, New Zealand, the Malaghan Institute of Medical Research specializes in the immune system and how it can be harnessed to improve human health. Key areas of focus range from cancer and asthma to infectious disease and gut and brain health.

Lead Research/Investigator

Dr Alissa Cait

Potential Association Between Dietary Fibre and Humoral Response to the Seasonal Influenza Vaccine

Influenza vaccination is an effective public health measure to reduce the risk of influenza illness, particularly when the vaccine is well matched to…

www.frontiersin.org