Acute Renal Failure due to Molnupiravire
Molnipiravir is a promising RNA-Dependent RNA-Polymerase enzyme inhibitor that has started to be used in the treatment of SARS-COV-2. I present the first case who was infected with the Omicron variant and developed acute renal failure due to the use of molnipiravir.67 Year-old male patient with the diagnosis of hypertension and chronic obstructive pulmonary disease developed severe nausea, vomiting and diarrhea with the use of drugs. In the patient's examinations, severe deterioration in kidney functions occurred. The patient who developed acute tubular necrosis was taken to hemodialysis twice. IV hydration and supportive treatments were started. In the follow-up, clinical and renal functions improved. In patients over 65 years of age and with comorbidities, the adverse effects of molnipiravir should be considered and followed closely.