The Playground

Quote from Fm1

And you are a circuit jocky who thinks he is smarter and more informed than all. They do research, you do character assignations. You knew nothing of seneff before the pandemic and now you are an expert on her research. You are so see thru

This is a misunderstanding. Unlike many here I admit to NOT being an expert on immunology.

As such, I can recognise any fellow Computer Scientists who unlike me pretend to be that.

You see, the beauty of the THH anti-vaxxer detection kit is that it does not require any evaluation of the science.

Anti-vaxxers such as Seneff betray themselves by pontificating as experts on such a very wide range of disparate fields - with only the anti-vaxxer slant as common theme - that no sensible person who did their journalistic research would take them seriously. In addition they pontificate on fields wildly different from any training they have had (in this case Seneff is a Computer Scientist).

You have continually misunderstood this about me. I have never claimed to be more expert than these clowns - or even as expert as they are.

However it is clear that they are much less expert than they claim to be, and also much less expert than the many real experts who disagree with them. Therefore I cannot take them seriously.

There is a well-known here equivalent. One reason many of us realised Rossi was a flake long ago is that if you believe him he must be an expert in some many different areas. One serendipitous world-shaking breakthrough - sure. But 5 - all in different areas of technology and science? It seems unlikely.

Omicron spawns BA.4 and BA.5 variants

Mere weeks after the BA.2 lineage of the Omicron coronavirus variant caused surges globally, two more Omicron spin-offs are on the rise worldwide. Their spread seems to stem from their capacity to infect people who were immune to earlier forms of Omicron and other variants. So far, the latest Omicron variants seem to be causing fewer deaths and hospitalizations — a sign that growing population immunity is tempering the immediate consequences of COVID-19 surges. Scientists caution that future variants won’t necessarily be milder than those that came before.

Nature | 7 min read

How brain washing works:: https://mainichi.jp/english/ar…20627/p2g/00m/0na/038000c

Japan::

There has never been a mask mandate in the country, but more than two years of the pandemic has made mask-wearing the polite thing to do, even as heat-related illnesses are emerging as a concern as Japan readies for a boiling summer.

Experts say many people are unaware the government has been proposing since May 20 that masks can be taken off in certain circumstances,....

The recommendation for outdoor mask usage now only applies to those conversing within two meters of each other.

There have been multiple cases of children who wore masks during gym classes being sent to hospital due to heat exhaustion or heatstroke.

My wive kick me too when I did remove my mask outdoors - what I almost ever did ...

Quote from Wyttenbach

How brain washing works:: https://mainichi.jp/english/ar…20627/p2g/00m/0na/038000c

Japan::

There has never been a mask mandate in the country, but more than two years of the pandemic has made mask-wearing the polite thing to do, even as heat-related illnesses are emerging as a concern as Japan readies for a boiling summer.

Experts say many people are unaware the government has been proposing since May 20 that masks can be taken off in certain circumstances,....

People in Japan have been wearing masks in public since the 1918 epidemic. They wear them all the time during flu season. Nearly everyone on a train platform may wear one. They use masks in place of wool mufflers, to keep the cold air out of their throats. A mask is more hygienic. So, if this is brainwashing, it was done 104 years ago, and it stuck.

Nice to know/learn. All the harms - wrong expectations drugs cause :: https://sebastianrushworth.com…ient-really-get-the-drug/

From Dr. Rushworth.

Quote from JedRothwell

They use masks in place of wool mufflers, to keep the cold air out of their throats. A mask is more hygienic.

I spent several months in Japan in all place over the country. Until CoV-19 only people with a health problem did wear masks in public. In total a low single digits percentage!

Now its 98% what is crazy as mask makes things worse not better in average!

2.5 years i watched this talk and not made 1 comment about this pLandemic, all that is needed is to watch the "Grand Jury" led by Fuellmich from Germany.

https://www.grand-jury.net/

It is just like a real court case with fact finding, motive etc etc. And soon to be followed up by real lawsuits and procedures. Go through the video's, it will take days but inform you for real instead of debating all the propaganda.

From Nature Briefing today, the future of COVID looks bleak:

What will come next?

That’s anybody’s guess. The parade of Omicron subvariants could continue, with new variants picking further holes in existing immunity. “Nobody can say BA.4/5 is the final variant. It is highly probable that additional Omicron variants will emerge,” says Kei Sato, a virologist at the University of Tokyo. Researchers have identified several spots on the spike protein that are currently recognized by the antibodies that are triggered by vaccination and previous infection, but that could mutate in future Omicron strains².

Another possibility is the emergence of a variant from a branch of the SARS-CoV-2 family tree different from the one that bore Omicron. Repeat Omicron infections could build broad immunity against successive lineages, creating an opening for a totally different SARS-CoV-2 variant that is unfamiliar to people’s immune responses, says Gupta. “The bar is getting higher and higher for a virus to take over.”

Increasingly, scientists think that variants including Omicron and Alpha probably originated from months-long chronic SARS-CoV-2 infections, in which sets of immune-evading and transmissibility-boosting mutations can build up. But the longer Omicron and its offshoots continue to dominate, the less likely it is that a totally new variant will emerge from a chronic infection, says Mahan Ghafari, who researches viral evolution at the University of Oxford, UK.

......and furthermore:

To succeed, future variants will have to evade immunity. But they could come with other worrying properties. Sato’s team found that BA.4 and BA.5 were deadlier in hamsters than was BA.2, and better able to infect cultured lung cells⁶. Epidemiology studies, such as the one led by Jassat, suggest that successive COVID-19 waves are getting milder. But this trend should not be taken for granted, Sato cautions. Viruses don’t necessarily evolve to become less deadly.

It’s also unclear when the next variant will appear. BA.4 and BA.5 started emerging in South Africa only a few months after BA.1 and BA.2, a pattern now being repeated in places including the United Kingdom and United States. But as global immunity from repeated vaccination and infection builds, Althaus expects the frequency of SARS-CoV-2 waves to slow down.

One possible future for SARS-CoV-2 is that it will become like the other four seasonal coronaviruses, the levels of which ebb and flow with the seasons, usually peaking in winter and typically reinfecting people every three years or so, Althaus says. “The big question is whether symptoms will become milder and milder and whether issues with long COVID will slowly disappear,” he says. “If it stays like it is now, then it will be a serious public-health problem.”

doi: https://doi.org/10.1038/d41586-022-01730-y

References

1. Tegally, H. et al. Preprint at medRxiv https://doi.org/10.1101/2022.05.01.22274406 (2022).
2. Cao, Y. et al. Nature https://doi.org/10.1038/s41586-022-04980-y (2022).

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3. Tuekprakhon, A. et al. Cell https://doi.org/10.1016/j.cell.2022.06.005 (2022).

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4. Khan, K. et al. Preprint at medRxiv https://doi.org/10.1101/2022.04.29.22274477 (2022).
5. Wang, Q. et al. Preprint at bioRxiv https://doi.org/10.1101/2022.05.26.493517 (2022).
6. Kimura, I. et al. Preprint at bioRxiv https://doi.org/10.1101/2022.05.26.493539 (2022).
7. Reynolds, C. J. et al. Science https://doi.org/10.1126/science.abq1841 (2022).

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Biden White House Paying $10.6 Billion for Pfizer's COVID-19 Paxlovid Flop

Biden White House Paying $10.6 Billion for Pfizer's COVID-19 Paxlovid Flop

Back in November 2021, the White House paid drugmaker Pfizer nearly $5.3 billion ($5,290,000,000) for 10 million treatment courses of its…

www.trialsitenews.com

David Gortler

Fellow at FDA / HHS Accountability Project | Ethics and Public Policy Center | Dr. Gortler is a pharmacologist and pharmacist and a Yale-trained bench research scientist in molecular biology

Back in November 2021, the White House paid drugmaker Pfizer nearly $5.3 billion ($5,290,000,000) for 10 million treatment courses of its experimental COVID-19 treatment. Paxlovid is an antiviral combination of nirmatrelvir and ritonavir.

Ritonavir was developed in 1989 and nirmatrelvir was developed in 2020. In other words, Paxlovid wasn’t developed from scratch to treat COVID-19; the compounds already existed.

In December 2021 Pfizer claimed initial study findings showed that Paxlovid cut the risk of hospitalization and death by nearly 90% in people with mild to moderate coronavirus infections. Without context this statement is grossly misleading. Just about everyone who gets the existing COVID-19 mutation will have mild or moderate disease yet, the drugmaker limited its study to people who were unvaccinated and who faced the greatest risk from the virus due to age or health problems, such as obesity. An updated more recent analysis from 1,153 patients (out of a possible 2,246 patients) showed a lackluster, non-significant 51% relative risk reduction. A sub-group analysis of 721 vaccinated adults with at least one risk factor for progression to severe COVID-19 showed a non-significant relative risk reduction in hospitalization or death (treatment arm: 3/361; placebo: 7/360)

According to Pfizer's official June 14th 2022 press release, results from the Phase 2/3 of the amended Paxlovid EPIC-SR (Evaluation of Protease Inhibition for COVID-19 in Standard-Risk Patients) study showed:

Paxlovid, the novel primary endpoint of self-reported, sustained alleviation of all symptoms for four consecutive days was not met.

Pfizer will cease enrollment into the EPIC-SR trial due to low rate of hospitalization or death in the standard-risk population.

Tucked within Pfizer’s press release was the following financial nugget for investors: “The results from these additional analyses are not expected to impact Pfizer’s full-year 2022 revenue guidance.” The reason for that is: Pfizer already has $5.3 billion in hand from taxpayers, and has locked in “blockbuster status” (defined as one billion dollars in sales of a single drug).

In addition to the $5.3 billion already committed, in January the U.S. announced a confidential additional “commitment” to order an additional 10 million doses (at the price of 5.3 billion dollars more, for a total of $10.6 billion) giving Pfizer highly sought after “super blockbuster status” (defined as having 10 billion dollars in sales of a single drug). “The administration is firmly committed to proceeding with the (additional) purchase” a White House official stated in April 2022.

Scitechdaily.com

Flu Vaccination Reduces Risk of Alzheimers

Over the course of four years, those who received at least one influenza vaccine were 40% less likely than their non-vaccinated peers to acquire Alzheimer’s disease, according to a new study from the University of Texas Health Science Center at Houston.

Researchers compared the risk of Alzheimer’s disease incidence between patients with and without prior flu vaccination in a large nationwide sample of U.S. adults aged 65 and older. The study was led by first author Avram S. Bukhbinder, MD, a recent alumnus of McGovern Medical School at UTHealth Houston, and senior author Paul. E. Schulz, MD, the Rick McCord Professor in Neurology at McGovern Medical School.

Back to the Future: Three Otolaryngologists Warned Us that Current COVID-19 Vaccines Wouldn’t Stop Viral Transmission

Back to the Future: Three Otolaryngologists Warned Us that Current COVID-19 Vaccines Wouldn’t Stop Viral Transmission

Even though systemic, respiratory vaccines typically provide limited protection against viral replication and airway-based shedding, this is the anchor of the…

www.trialsitenews.com

Even though systemic, respiratory vaccines typically provide limited protection against viral replication and airway-based shedding, this is the anchor of the developed world’s COVID-19 mass vaccination scheme to eradicate the pathogen strategy with countless billions spent to date. TrialSite has tracked some scientists who articulate the importance of and need for mucosal vaccination strategies, but few in organized medicine listened. While the most advanced, well-capitalized healthcare systems of the world developed a unifying response to SARS-CoV-2 based on an mRNA-based IgG response to prevent SARS-CoV-2 replication, data early on, according to some critics, revealed challenges associated with the current approach. For example, nasal swab analysis post adenovirus and mRNA-based COVID-19 vaccine administration turned up persistent evidence for a lingering SARS-CoV-2 pathogen according to three ear, nose, and throat specialists from Johns Hopkins University and Harvard Medical School. This implies that although the current vaccines may reduce severe illness and even inhibit some viral transmission, it by no means eliminates all transmission. This isn’t a new finding, as this argument was put forth by Drs. Benjamin S. Bleier, Murugappan Ramanathan, and Andrew Lane, but it’s worth a revisit to understand better why the scientific and healthcare powers-that-be probably understood there would be viral transmission even after mass vaccination using state-of-the-art systemic mRNA COVID-19 vaccines.

The three authors have significant otolaryngological expertise and are currently employed as professors and provider-scientists at both Johns Hopkins University and Harvard Medical School and Massachusetts Eye and Ear.

Before delving into the important scientific contribution of the three otolaryngologists, TrialSite provides a brief look back in history when the topic of COVID-19 mucosal vaccine strategies was raised by this media. For example, in “America’s Vaccine-centric Strategy to overcome SARS-CoV-2 Failing While Adequate Universal Testing Data Collection Grossly Inadequate,” TrialSite shared the thinking of the outspoken Dr. Eric Topol at Scripps, who emphasized nearly a year ago the importance of mucosal immunity and the need to consider intranasal vaccines. It turns out he wasn’t alone. Several prominent physicians and scientists were already fully aware of the limitations of the current batch of vaccine products.

Regarding the piece published by Drs. Bleier, Ramanathan, and Lane on December 15, 2020, in the journal “Otolaryngology-Head and Neck Surgery," the three respected academic physician-scientists raised a fundamental concern back then that few seemed to heed

Quote from Wyttenbach

I spent several months in Japan in all place over the country. Until CoV-19 only people with a health problem did wear masks in public. In total a low single digits percentage!

Now its 98% what is crazy as mask makes things worse not better in average!

I suggest this song to any mask obsessed friend. It's well known and called "One Moment in Time", famously sung by Whitney Houston for the 1988 Olympics in South Korea. Anyways, the following version from late 2020 captures the Covid moment in time (like closed kids' playgrounds!) and has an inspiring de-masking scene about 20 seconds from the end. OK, the singer Roberta Battaglia is from Toronto (born to Italian parents) so maybe I'm biased. Amazing that she was just eleven at the time.

Quote from Dr Richard*

BA.4 and BA.5 started emerging in South Africa only a few months after BA.1 and BA.2, a pattern now being repeated in places including the United Kingdom and United States.

Sad to say that the most likely reason for this is the extensive live of the gay community. Monkey pocks exclusively targeted the gays as AIDS did some 40 years ago. In RSA close to 10 million immune suppressed people (under AIDS therapy) live, that are perfect bioreactors for new virus.

As said "vaccination" in a pandemic usually is more deadly than the pandemic itself. We know this from the cheated phase III study of Pfizer/Moderna where more people died in the vaccine group than in the placebo group...

Quote from ZenoOfElea

Over the course of four years, those who received at least one influenza vaccine were 40% less likely than their non-vaccinated peers to acquire Alzheimer’s disease, according to a new study from the University of Texas Health Science Center at Houston.

They say also ::

“Since there is evidence that several vaccines may protect from Alzheimer’s disease, we are thinking that it isn’t a specific effect of the flu vaccine,” said Schulz, who is also the Umphrey Family Professor in Neurodegenerative Diseases and director of the Neurocognitive Disorders Center at McGovern Medical School.

Wyttenbach

Yes, good point, very hard to say.

The hypothesized protective "effect" does not stop somebody getting Alzheimer's but may delay it by several years.

The suggestion that catching influenza itself may increase the risk of Alzheimer's due to inflammation or some other change to the immune system sounds plausible, but I am no expert.

However, as you say, the effect may not be specific to the flu vaccine. It is possible it might be something other than the vaccine, maybe these people also take vitamin tablets or whatever.

We know don't know what the mechanism of the beneficial effect might be and we still don't even know the cause of Alzheimer's.

So interesting research but much more to be investigated.

I am humbled. Doctor Rossi chose my very own full name as an alias for presenting his latest suggestion to himself and the group. I'm breaking out some red wine now in celebration. Then I'll clean out my neighbour's eavestrough which I've put off for two days now. If you don't hear from me, I fell from the ladder, badly.

Is that guy still around?

He is only relevant to himself, his sock puppets and the precious few blithering idiots that remain conned.

Quote from Roseland67

Is that guy still around?

He is only relevant to himself, his sock puppets and the precious few blithering idiots that remain conned.