Sorry, I put that ^ in the other thread because I thought it might be of note for Sindre.
Hydrogenation without H2 Using a Palladium Membrane Flow Cell
Ryan P. Jansonius, Aiko Kurimoto, Antonio M. Marelli, Aoxue Huang, Rebecca S. Sherbo, Curtis P.Berlinguette
Electrocatalytic palladium membrane reactors (ePMRs) use electricity to hydrogenate organic molecules at ambient temperature and pressure. These benign reaction conditions position ePMRs as a sustainable alternative to thermochemical hydrogenation, which requires high-temperature and high-pressure reaction conditions. However, ePMRs suffer from slow reaction rates and a limited understanding of the factors that govern reaction performance in these devices. In this work, we report the design and validation of an ePMR flow cell. This flow cell increases reaction rates 15-fold and current efficiencies by 30% relative to H-cell reactors. We use this device to reveal that the hydrogen content in the palladium membrane governs the speed and selectivity of hydrogenation reactions, while the amount of hydrogen gas evolved at the palladium surface is deterministic of current efficiency. We contend that this flow cell, which enables hydrogenation without hydrogen gas, is an important step for translating ePMRs into practice.
Curtis Berlinguette reports articles, exploitinge Cold Fusion experiments (Hydrogen in metal), in non LENR applications, as Pharmacy.Quote
Electrolytic deuteration of unsaturated bonds without using D2
Site-selective deuteration of C–H bonds increases the lifetime and efficacy of drug molecules. Although effective methods to form C(sp2)–D bonds are known, processes for making C(sp3)–D bonds often have low site selectivity, require expensive and unrecoverable D2 gas, or use stoichiometric reagents. Here we report cost-efficient and site-selective reductive deuteration using a tandem electrochemical chemical palladium membrane reactor. This architecture mediates the chemical reaction of deuterium atoms (derived from reusable D2O in an electrochemical compartment) with alkynes, aldehydes and imines. The formation of C(sp3)–D and C(sp2)–D bonds in the isolated chemical compartment is made possible by the deuterium-selective permeability of the membrane that partitions the electrochemical compartment from the chemical compartment. We have utilized the reactor for the deuteration step in the construction of a common drug, cinacalcet, to demonstrate that this method can be used to incorporate deuterium atoms in a pharmaceutical.Quote
From cold fusion to pharmaceuticals
Revisiting "cold fusion" led us to discover the electrolytic hydrogenation/deuteration reactor that is electrically-driven and uses water as a hydrogen/deuterium source. This technology opens new avenues for using renewable energy to make valuable chemicals, including pharmaceuticals.
Combining pressure and electrochemistry to synthesize palladium superhydrides
"This work was partially supported by Google and by the DOE/NNSA and NSF-DMR (R.J.H.) The Authors would like to thank helpful discussions with Yet-Ming Chiang, Matt Trevithick and Florian Metzler."
[.... Observation of non-exponential decay of x-ray and γ lines from Co-57 on steel plates - Florian Metzler, Peter Hagelstein and Siyuan Lu, JCMNS Vol.24]
I am happy to read another useful application of the research on LENR by the team of Pr. Berlinguette in NATURE CATALYSIS.
Years ago, we have demonstrated that our palladium cathodes were producing atomic hydrogen. It is probably the reagent of Berlinguette team.
In this article, we published the deuteriation of benzoquinone into hydroquinone by a palladium cathode. Our goal was not to do chemistry, but to make paper that changes color on contact with atomic hydrogen. (or in contact with atomic deuterium) (I write « palladium » by mistake instead of "deuterium" in my previous post, sorry.)