Covid-19 News

  • NIH neuroscientists isolate promising mini antibodies against COVID-19 from a llama


    https://www.nih.gov/news-event…es-against-covid-19-llama


    A nanobody is a special type of antibody naturally produced by the immune systems of camelids, a group of animals that includes camels, llamas, and alpacas. On average, these proteins are about a tenth the weight of most human antibodies. This is because nanobodies isolated in the lab are essentially free-floating versions of the tips of the arms of heavy chain proteins, which form the backbone of a typical Y-shaped human IgG antibody. These tips play a critical role in the immune system’s defenses by recognizing proteins on viruses, bacteria, and other invaders, also known as antigens.

    • Official Post

    drdrewpinsky


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    As requested, @drdrewpinsky has his protocol here for you. If you want a Monicolonal Antibody, have your physician call Corum at 866-799-5830. Dr. Drew Health Wise: It’s slow and go, fever down, better than yesterday. Thanks to all the doctors who came to help early,

  • why are hospitals balking at using approved treatments such as the anti body treatment Trump received?

    Most likely Trump got no treatment. He did use Ivermectin as a prevention. Of course he still could be PCR positive and infect others but certainly he was never sick.


    Why do we know this? Trump uses Soolantra creme...

    Trump owns shares of Gilead as most mafia members do too. Directly or indirectly via special fonds. (ask e.g. Blackrock)

    As requested, @drdrewpinsky has his protocol here for you.


    There is no need for adventure therapies! 2$ for Ivermectin (India price) or 8$ - US or German prize is your ticket to health. But this 8$ is for the horse version! (That works fine as we tested! )

  • why are hospitals balking at using approved treatments such as the anti body treatment Trump received?

    I have not read that they are balking. My understanding is that antibody medicine is extremely expensive and only available in tiny amounts, so they cannot use it. They would use it if they could.


    Of course most doctors and hospitals are counting the vaccine. There have been some delays distributing it but they are doing pretty well. I think they distributed 14 million doses in two weeks where the goal was 20 million. That's not bad. There may be ever worse delays administering it, but I gather that may be largely caused by delays in reporting, not actual delays.

  • Most likely Trump got no treatment.

    Do you really think the doctors would go before the public and say he got antibody treatment, but they were lying? You don't think someone would find out?


    You have strange imagination. You believe any damn conspiracy theory, no matter how absurd or impossible, if it lets you disbelieve the prosaic truth. Why are you so anxious to avoid believing uncontroversial things? Why does it even matter whether Trump got one treatment rather than another? Assuming you believe in the magical cock-and-bull treatments you advocate, surely that means other treatments also work? If the kind of garbage you promote actually works, then just about anything should work. Eye of newt and toe of frog. A glass of orange juice and a magic spell. It is amazing anyone every gets sick, if that's all it takes is to cure anything.


  • You believe any damn conspiracy theory

    JED: It's you that believes all news (nonsense) you see! This announcement was just a commercial for manipulating Stocks nothing more.


    It is crazzy that you believe somebody would allow to treat "the most important" person of USA with an adventure drug...

    Of course he did also lie about the Gielad crap Remdesivir that he certainly did not get for the same reason as it really is dangerous crap!

  • Over 50,000 new cases a day for the last 5 days in the UK, Averaging something like 650 covid positive deaths a day for the same period.

    We had 10'000 cases/day with 8.5 million people. So you would need 80'000 to top this.

    Germany did distribute FP98 masks to all old people some weeks ago. Why does the UK not copy this? Care home employees here use them since months - but still to many deaths...

    Why do they in UK not distribute high dose V-D3?? +Zinc?

  • Cutting corners ?


    Amid shortages, scientists weigh benefits of a single Covid-19 doses versus two


    https://news.google.com/articl…=en-US&gl=US&ceid=US%3Aen


    Food and Drug Administration (FDA) analyses of both the Moderna and Pfizer vaccines found that a single dose of either appears to provide some protection against the coronavirus.


    The efficacy of one Moderna vaccine dose was around 80 to 90 percent, researchers found in stage 3 trials ahead of its approval by the US regulator in January.


    Scientists found that the Pfizer-BioNTech jab is 70 percent effective with one dose compared to 95 percent effective with two.


    After approving the Oxford-AstraZeneca vaccine, British regulators said it was around 70 percent effective in the 12 weeks after the first dose.

  • As a new Covid-19 treatment arrives, hospitals scramble to solve logistical and ethical challenges


    https://www.statnews.com/2020/…istribution-difficulties/


    The medication is bamlanivimab, Eli Lilly’s monoclonal antibody, and it’s meant for keeping high-risk patients out of the hospital. But its use comes with a Venn diagram of difficulties. Hospitals need to find space and staff to administer it at a time when there’s hardly enough of either to treat those who are gravely sick, build a system to identify eligible patients, and figure out an ethical way to ration it — all without knowing exactly how well the treatment works.


    7 weeks and the problems still are not worked out and patients dying at record numbers. I don't know about the treatment but it is an approved treatment and patients are not getting it. Something is really wrong about this.

  • FDA on use of ivermectin in treatment of covid


    FAQ: COVID-19 and Ivermectin Intended for Animals


    Q: Should I take ivermectin to prevent or treat COVID-19?

    A: No. While there are approved uses for ivermectin in people and animals, it is not approved for the prevention or treatment of COVID-19. You should not take any medicine to treat or prevent COVID-19 unless it has been prescribed to you by your health care provider and acquired from a legitimate source.


    A recently released research articleExternal Link Disclaimer described the effect of ivermectin on SARS-CoV-2 in a laboratory setting. These types of laboratory studies are commonly used at an early stage of drug development. Additional testing is needed to determine whether ivermectin might be appropriate to prevent or treat coronavirus or COVID-19.


    Q: Is there an emergency use authorization for ivermectin in the U.S. to prevent or treat coronavirus or COVID-19?

    A: No. FDA has created a special emergency program for possible therapies, the Coronavirus Treatment Acceleration Program (CTAP). It uses every available method to move new treatments to patients as quickly as possible, while at the same time finding out whether they are helpful or harmful. We continue to support clinical trials that are testing new treatments for COVID so that we can gain valuable knowledge about their safety and effectiveness.


    Q: What is ivermectin approved for in the U.S.?

    A: Ivermectin tablets are approved for use in humans for the treatment of some parasitic worms (intestinal strongyloidiasis and onchocerciasis) and ivermectin topical formulations are approved for human use by prescription only for the treatment of external parasites such as headlice and for skin conditions such as rosacea.


    Ivermectin is FDA-approved for use in animals for prevention of heartworm disease in some small animal species, and for treatment of certain internal and external parasites in various animal species. People should never take animal drugs, as the FDA has only evaluated their safety and effectiveness in the particular species for which they are labeled. Using these products in humans could cause serious harm.


    Q: Is there any danger to humans taking ivermectin?

    A: There are approved uses for ivermectin in people and animals but it is not approved for the prevention or treatment of COVID-19. You should not take any medicine to treat or prevent COVID-19 unless it has been prescribed to you by your health care provider and acquired from a legitimate source.


    Some of the side-effects that may be associated with ivermectin include skin rash, nausea, vomiting, diarrhea, stomach pain, facial or limb swelling, neurologic adverse events (dizziness, seizures, confusion), sudden drop in blood pressure, severe skin rash potentially requiring hospitalization and liver injury (hepatitis). Laboratory test abnormalities include decrease in white cell count and elevated liver tests. Any use of ivermectin for the prevention or treatment of COVID-19 should be avoided as its benefits and safety for these purposes have not been established. Data from clinical trials are necessary for us to determine whether ivermectin is safe and effective in treating or preventing COVID-19.


    Q: What should I do if the ivermectin products I purchase for use in my animals are not available at my typical retailer?

    A: Ivermectin is an important part of a parasite control program for certain species and should only be given to animals for approved uses or as prescribed by a veterinarian in compliance with the requirements for extra-label drug use. Due to potentially elevated interest in ivermectin following the new research, some products may not be available. If you are having difficulty locating a particular ivermectin product for your animal(s), the FDA recommends that you consult with your veterinarian.


    Q: What is the FDA doing to protect people from fraudulent COVID-19 products?

    A: We have established a cross-agency task force dedicated to closely monitoring for fraudulent COVID-19 products. We have reached out to major retailers to ask for their help in monitoring online marketplaces for fraudulent COVID-19 products. Products sold are subject to FDA investigation and potential enforcement action if they claim to prevent, diagnose, treat, or cure COVID-19 and have not demonstrated safety and effectiveness for that intended use. The task force has already worked with retailers to remove dozens of these types of product listings online.


    The FDA and the Federal Trade Commission (FTC) issue warning letters to companies that violate federal law and pose significant risks to patient health by selling unapproved products with fraudulent claims to treat or prevent COVID-19. View the warning letters for more information.


    Additional Information

    FDA Letter to Stakeholders: Do Not Use Ivermectin Intended for Animals as Treatment for COVID-19 in Humans

  • Laboratory test abnormalities include decrease in white cell count and elevated liver tests. Any use of ivermectin for the prevention or treatment of COVID-19 should be avoided as its benefits and safety for these purposes have not been established. Data from clinical trials are necessary for us to determine whether ivermectin is safe and effective in treating or preventing COVID-19.

    Outraging nonsense: In Egypt Ivermectin daily is given to millions of people with no adverse effects...But people in rich countries taking tons if other medicaments or people suffering from civilization illness are a different story...

    So FDA uses the ill people as an excuse to not treat teh healthy one....

    Additional Information

    FDA Letter to Stakeholders: Do Not Use Ivermectin Intended for Animals as Treatment for COVID-19 in Humans

    Of course dear shareholders we ensure that you can can get 100..1000x market price for the agreed use of Ivermectin...


    But the Horse version is safe and e.g. the only one initially used in Argentina and its 1000x cheaper...

    I used it too, some years ago, on advice of a pharmacist!

    Short: FDA is the most corrupt bunch of mafia people in USA! As said 80% paid by big pharma for drug advises. (Same as Boeing MAX case!)

  • From 11 years ago. Anyone with questions on ivermectin please read this NIH study. After reading ask yourself, why has the FDA not given this drug at least emergency use. People are now dying at record numbers, what will it take for the FDA to grant emergency use. This can be used as an outpatient treatment giving immediate relief to overwhelmed hospitals. Will it take 195,000 deaths in the first 5 weeks of the second wave as it did in 1918 to get the FDA off their asses and help save lives. I believe it's a reasonable question that demands answers!


    Ivermectin, ‘Wonder drug’ from Japan: the human use perspective


    Abstract

    Discovered in the late-1970s, the pioneering drug ivermectin, a dihydro derivative of avermectin—originating solely from a single microorganism isolated at the Kitasato Intitute, Tokyo, Japan from Japanese soil—has had an immeasurably beneficial impact in improving the lives and welfare of billions of people throughout the world. Originally introduced as a veterinary drug, it kills a wide range of internal and external parasites in commercial livestock and companion animals. It was quickly discovered to be ideal in combating two of the world’s most devastating and disfiguring diseases which have plagued the world’s poor throughout the tropics for centuries. It is now being used free-of-charge as the sole tool in campaigns to eliminate both diseases globally. It has also been used to successfully overcome several other human diseases and new uses for it are continually being found

  • Use of Ivermectin Is Associated With Lower Mortality in Hospitalized Patients With Coronavirus Disease 2019

    The ICON Study


    https://journal.chestnet.org/a…-3692(20)34898-4/fulltext


    Results

    Two hundred eighty patients, 173 treated with ivermectin and 107 without ivermectin, were reviewed. Most patients in both groups also received hydroxychloroquine, azithromycin, or both. Univariate analysis showed lower mortality in the ivermectin group (15.0% vs 25.2%; OR, 0.52; 95% CI, 0.29-0.96; P = .03). Mortality also was lower among ivermectin-treated patients with severe pulmonary involvement (38.8% vs 80.7%; OR, 0.15; 95% CI, 0.05-0.47; P = .001). No significant differences were found in extubation rates (36.1% vs 15.4%; OR, 3.11; 95% CI, 0.88-11.00; P = .07) or length of stay. After multivariate adjustment for confounders and mortality risks, the mortality difference remained significant (OR, 0.27; 95% CI, 0.09-0.80; P = .03). One hundred ninety-six patients were included in the propensity-matched cohort. Mortality was significantly lower in the ivermectin group (13.3% vs 24.5%; OR, 0.47; 95% CI, 0.22-0.99; P < .05), an 11.2% (95% CI, 0.38%-22.1%) absolute risk reduction, with a number needed to treat of 8.9 (95% CI, 4.5-263).

  • this was posted recently as a failed trial by a member here. This is the results of that study. Its been posted before but not read by all


    five day course of ivermectin for the treatment of COVID-19 may reduce the duration of illness


    https://www.ijidonline.com/art…-9712(20)32506-6/fulltext


    Highlights

    Ivermectin, an FDA-approved anti-parasitic agent, was found to be an inhibitor of SARS-CoV-2 replication in the laboratory.

    Ivermectin may be effective for the treatment of early-onset mild Covid-19 in adult patients. Early viral clearance of SARS-CoV-2 was observed in treated patients.

    Remission of fever, cough and sore throat did not differ between those treated with or without ivermectin. No severe adverse event observed with the longer duration of ivermectin use.

    Larger trials will be needed to confirm these preliminary findings.


    NOW THE QUESTION, WILL WE EVER GET THESE TRIALS ? Sadly I doubt it

  • A few COVID-19 survivors don’t have their sense of taste or smell back, and doctors aren’t sure they ever will


    https://www.chicagotribune.com…story.html?outputType=amp


    diminished sense of smell, called anosmia, has emerged as one of the telltale symptoms of COVID-19, the illness caused by the coronavirus. It is the first symptom for some patients, and sometimes the only one. Often accompanied by an inability to taste, anosmia occurs abruptly and dramatically in these patients, almost as if a switch had been flipped.


    Most regain their senses of smell and taste after they recover, usually within weeks. But in a minority of patients like Hansen, the loss persists, and doctors cannot say when or if the senses will return.


    Do doctors understand zinc deficenccy


    https://www.oatext.com/propose…istribution.php#gsc.tab=0


    Zinc deficiency is well known to cause anosmia and taste dysfunction. This is because one of the enzymes critical to maintain taste and smell function is a zinc dependent metalloenzyme called carbonic anhydrase (CA) [9]. Interestingly, different formulations of intranasal Zn have also been shown to cause anosmia, but the mechanisms for toxicity are complex, including oxidative stress, ATP depletion, cytoskeletal changes and apoptosis of olfactory neuronal cells, and is affected by many factors, such as concentration of zinc tested, the length of exposure, the cell type, and the presence of other toxic chemicals [10].


    Myeloid and lymphoid cells manipulate intracellular and extracellular zinc metabolism via Zn binding proteins and transporters in response to immunological signals and infections [11]. Zinc is considered an acute phase reactant and Zn levels are redistributed during infection [12]. Systemic Zn deficiency is associated with decreased Th1 cytokines, interferon-gamma and interleukin (IL)-2, and unchanged production of Th2 cytokines (IL-4, IL-6, and IL-10); which causes a shift in Th1 to Th2 balance towards Th2 cytokine predominance [13].

  • vitamin deficenccy is a disaster unfolding right in front of your wide-open eyes . This is THE wake-up call medicine has needed. Prevention


    Long haulers take notice, every symptom points to a vitamin deficenccy and this study will help to understand that.


    Vitamins and Minerals for Energy, Fatigue and Cognition: A Narrative Review of the Biochemical and Clinical Evidence


    https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7019700/


    Abstract

    Vitamins and minerals are essential to humans as they play essential roles in a variety of basic metabolic pathways that support fundamental cellular functions. In particular, their involvement in energy-yielding metabolism, DNA synthesis, oxygen transport, and neuronal functions makes them critical for brain and muscular function. These, in turn, translate into effects on cognitive and psychological processes, including mental and physical fatigue. This review is focused on B vitamins (B1, B2, B3, B5, B6, B8, B9 and B12), vitamin C, iron, magnesium and zinc, which have recognized roles in these outcomes. It summarizes the biochemical bases and actions of these micronutrients at both the molecular and cellular levels and connects them with cognitive and psychological symptoms, as well as manifestations of fatigue that may occur when status or supplies of these micronutrients are not adequate.

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