Covid-1984, a criminal agenda of the globalist mafia
UK coronavirus variant could be more lethal than original strain, possibly by up to 70 percent, scientists say
https://news.google.com/articl…=en-US&gl=US&ceid=US%3Aen
The coronavirus variant that originated in the United Kingdom is likely deadlier than the original strain, according to a new assessment released on Friday by British government scientists.
In the report, which evaluated multiple studies, the scientists estimated that the strain, known as B.1.1.7, could be 30% to 70% deadlier than the original virus.
Studies have already shown the UK strain to be more transmissible and Prime Minister Boris Johnson announced last month that it could also be "associated with a higher degree of mortality."
The assessment confirmed that concern, but the scientists also said there would need to be more extensive studies conducted on deaths.
Meanwhile, the more contagious variant has been circulating throughout the world and the US. It has been detected in at least 82 countries, according to The New York Times. A study published earlier this month found the UK variant was spreading so quickly across the US that the case count involving that strain was doubling about every ten days.
"These findings show that B.1.1.7 will likely become the dominant variant in many US states by March 2021, leading to further surges of COVID-19 in the country, unless urgent mitigation efforts are immediately implemented," the paper said.
The study also said the UK variant is 35% to 45% more transmissible than other strains spreading in the US. Scientists have also expressed concern that the variant could be developing a mutation that would help it evade vaccines.
Alien Cells May Explain COVID 'Brain Fog'
https://www.medscape.com/viewarticle/945774
The long-term neurologic symptoms such as "brain fog" experienced by some patients with COVID-19 may be caused by a unique pathology — the occlusion of brain capillaries by large megakaryocyte cells, a new report suggests.
The authors report five separate post-mortem cases from patients who died with COVID-19 in which large cells resembling megakaryocytes were identified in cortical capillaries. Immunohistochemistry subsequently confirmed their megakaryocyte identity.
They point out that the finding is of interest as — to their knowledge — megakaryocytes have not been found in the brain before.
The observations are described in a research letter published online February 12 in JAMA Neurology.
Bone Marrow Cells in the Brain
Lead author David Nauen, MD, PhD, a neuropathologist from Johns Hopkins University, Baltimore, Maryland, told Medscape Medical News he identified these cells in the first analysis of post-mortem brain tissue from a patient who had COVID-19.
"Some other viruses cause changes in the brain such as encephalopathy, and as neurologic symptoms are often reported in COVID-19, I was curious to see if similar effects were seen in brain post-mortem samples from patients who had died with the infection," Nauen said.
On his first analysis of the brain tissue of a patient who had COVID-19, Nauen saw no evidence of viral encephalitis, but he observed some "unusually large" cells in the brain capillaries.
"I was taken aback; I couldn't figure out what they were. Then I realized these cells were megakaryocytes from the bone marrow. I have never seen these cells in the brain before. I asked several colleagues and none of them had either. After extensive literature searches, I could find no evidence of megakaryocytes being in the brain," Nauen noted.
Megakaryocytes, he explained, are "very large cells, and the brain capillaries are very small — just large enough to let red blood cells and lymphocytes pass through. To see these very large cells in such vessels is extremely unusual. It looks like they are causing occlusions."
By occluding flow through individual capillaries, these large cells could cause ischemic alteration in a distinct pattern, potentially resulting in an atypical form of neurologic impairment, the authors suggest.
"This might alter the hemodynamics and put pressure on other vessels, possibly contributing to the increased risk of stroke that has been reported in COVID-19," Nauen said. Although, he reported, none of the samples he examined came from patients with COVID-19 who had had a stroke.
Other than the presence of megakaryocytes in the capillaries, the brain looked normal, he said. He has now examined samples from 15 brains of patients who had COVID-19 and megakaryocytes have been found in the brain capillaries in five cases.
more evidence for vitamin D
Lots of petri- dishes out there...... Treat early!
COVID-19 virus variants are evolving ‘escape’ mutations, and immune-compromised patients provide a breeding ground
https://www.inquirer.com/healt…10212.html?outputType=amp
For more than two months, a 73-year-old cancer patient fought COVID-19 at the University of Pittsburgh Medical Center.
His doctors did genomic sequencing on blood and respiratory samples collected as he got better and then, suddenly, worse. They chronicled the emergence of a slew of coronavirus mutations — including an ominous one that is part of strains from the United Kingdom and South Africa now sweeping around the globe, threatening the effectiveness of new vaccines
The thing is, the UPMC researchers did the sequencing after the patient died, months before those countries identified the variants and sounded alarms in December.
Similar reports of patients who succumbed or barely survived worrisome new coronavirus strains – months before scientists were on the lookout for those particular strains – have been published by researchers in Boston and London, and at the National Institutes of Health
These patients all had severely weakened immune systems, long-running COVID-19 infections, and treatments intended to boost their immune response. For the virus, they were the perfect hosts for speeding up natural evolution and accumulating “escape” mutations – DNA changes that would give the microbe a survival advantage and enable it to outcompete other variants if it started spreading in the community.
What this suggests, researchers say, is that mutations that make the virus more transmissible and more intractable are arising repeatedly, spontaneously, independently — and largely undetected — around the world. Scientists call it “convergent evolution.”
“It’s pretty remarkable that many of the mutations that characterize the U.K. and South African variants actually first emerged in the spring and summer of 2020, months before news reports of these new variants began to circulate,” said Ghady Haidar, a transplant infectious disease physician at UPMC and senior author of a case report on the 73-year-old cancer patient. “This is exactly what happened with our patient: We discovered all these mutations and were stunned at how quickly the virus evolved, but it wasn’t until the winter of 2020 that we realized that these are the same mutations that the U.K. is reporting.”
This phenomenon has implications for treating immune-compromised patients, for new waves of the pandemic, and, most of all, for vaccinating our way out of it.
A variant grows dominant
Viruses invade cells, hijack the cell’s molecular machinery, replicate, then break out and infect more cells.
The novel coronavirus uses its thorn-like “spike” protein to bind to a receptor called ACE2 on the surface of cells and then break in.
Cells lining the nose and lungs are particularly laden with ACE2.
As the virus copies itself, it occasionally makes errors in its genetic code – a typo here, a deleted letter there. Most mistakes are harmful or insignificant to the virus, but a few are beneficial.
The British variant, known as B.1.1.7, has a collection of mutations, including eight that make the spike protein bind more tightly to ACE2. As a result, the virus infects more cells, the viral load grows, and transmission increases. The British variant is now in 60 countries, including the U.S., where the Centers for Disease Control and Prevention predicts it will become dominant next month.
The South African strain and a similar one that emerged independently in Brazil are potentially even more threatening. Not only do they attach to airway cells efficiently, but they also block the action of certain disease-fighting antibodies — including some antibodies marshaled by the new COVID-19 vaccines.
more evidence for vitamin D
The paper: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3771318
Key input: Taking V-D3 takes 1-2 weeks to convert to Calcifediol. That's why you should take high doses at single point in time because Calcifediol halve live is pretty long.
UK coronavirus variant could be more lethal than original strain, possibly by up to 70 percent, scientists say
Warning: This (40-70%) is spread by big pharma to delay lock-down lifts and used as a mean - spread fear - to forced people into vaccination. German studies report no change in the risk profile for 1.1.71 at all. We here also see no difference.
The paper: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3771318
Key input: Taking V-D3 takes 1-2 weeks to convert to Calcifediol. That's why you should take high doses at single point in time because Calcifediol halve live is pretty long.
Warning: This (40-70%) is spread by big pharma to delay lock-down lifts and used as a mean - spread fear - to forced people into vaccination. German studies report no change in the risk profile for 1.1.71 at all. We here also see no difference.
Calcifediol has a half life of 11 days, not long at all meaning supplementation in the fall, winter and spring, every day is essential to maintaining proper levels. After turning 60 I began taking 5000 units a day from August to may and this year added a dose of 20,000 units once a month. No problems.
As for b117 if more infectious more deaths, 200,000 americans have died in the last 3 months, nothing more needs to be said about that but watch come the first of March as cases around the world begin rising again and b117 will be a major cause of it.
As for b117 if more infectious more deaths, 200,000 americans have died in the last 3 months, nothing more needs to be said about that but watch come the first of March as cases around the world begin rising again and b117 will be a major cause of it.
In fact it is a bit more infectious what increases the numbers of deaths but not at a higher rate than the cases do increase. It's the other way round.
Here we see more children are getting infected so this is part of the higher count. But no children do develop serious cases. May be in over fated USA/GB this is different.
One thing that is very serious is CoV-19 infection/death induction by the Pfizer vaccine in the first two weeks. This could clearly be identified in the Israel statistics. I only recommend people to use the Moderna vaccine if they like to play guinea pig. J&J, Astra Zeneca and the Russian vaccine are several orders of magnitude more save.
Unexplained Covid-19 cases prompt first lockdown in New Zealand since August
"We all get that sense of ‘Not again,'" Prime Minister Jacinda Ardern told a news conference.
https://news.google.com/articl…=en-US&gl=US&ceid=US%3Aen
WELLINGTON, New Zealand — New Zealand’s largest city of Auckland will go into a three-day lockdown beginning just before midnight Sunday following the discovery of three unexplained coronavirus cases in the community.
Prime Minister Jacinda Ardern announced the move after an urgent meeting with other top lawmakers in the Cabinet. She said they decided to take a cautious approach until they find out more about the outbreak, including whether the infections are of the more contagious variants.
Is this the start of the next wave?
Newest Ivermectin prevention study from Peru: https://papers.ssrn.com/sol3/papers.cfm?abstract_id=3765018
(guess has been linked once as an preprint)
75% reduction in death in broad application.
90% with adapted treatment:
Mortality rates for IVM treatment at higher doses, totaling at least 400 μg/kg over two consecutive days, were about one-tenth those of controls, with statistically significant improvement in other case parameters.1
Still not high dose ! as in Egypt with 800ug or 1200ug.
DR Paul Offit answers question
about vaccines. 18:00 to 59:00
minute marks.Can be followed
above Normal Speed.
This is called "off label" use. If the doctor harms or kills the patient with an overdose, that would violate FDA rules
Angel advised offlabel ivermectin .> Did not violate FDA rules
Louis Gossett TM 01:00
"i called them angels one of those angels
they called and said "i have something for you""
The angel's advice worked better than the Georgia Hospital
Good news, latest data from Israel confirm effectiveness of Pfizer’s vaccine:
Batch of homegrown coronavirus mutations seen in US
https://news.google.com/articl…=en-US&gl=US&ceid=US%3Aen
(CNN)Researchers said Sunday they have identified a batch of similar troubling mutations in coronavirus samples circulating in the United States. They've not only drawn attention to them; they've come up with a better shorthand for referring to them. They've named them after birds.
The mutations all affect the same stretch of the spike protein -- the knob-like extension on the outside of the virus that it uses to dock onto the cells it infects, the researchers wrote in a pre-print report. It's not peer reviewed yet, but researchers are rushing such findings online to share them quickly with other experts.
The genetic stretch that is mutated, or changed, is called 677. The various changes are so similar that the researchers think evolution favors these particular variants. And it's in a troubling place, said Vaughn Cooper, director of the Center for Evolutionary Biology and Medicine at the University of Pittsburgh School of Medicine, who worked on the study.
This stretch of Spike is important because of its proximity to a region key for virulence," Cooper told CNN via email.
"We actually think these mutations are relatively rare (compared to other types of mutation), but they are disproportionately selected when then occur," he added.
The team has been reviewing genomic sequences deposited into GISAID, a global database that researchers are using to share genetic information about the virus. It's where scientists first noticed the rise of troubling new variants such as B.1.1.7, first seen in the United Kingdom, and B.1.351, first seen in South Africa.
In late January of 2021, our two independent SARS-CoV-2 genomic surveillance programs, based at the University of New Mexico Health Sciences in Albuquerque, New Mexico and the Louisiana State University Health Sciences Center in Shreveport, Louisiana, each noticed increasing numbers of ... viruses carrying an S:Q677P mutation, and that this variant had increased in frequency in samples collected in late 2020 to mid-January," the researchers wrote.
That shorthand -- Q677P-- refers to the specific change in the amino acid making up that part of the spike protein.
They've identified seven similar mutations at 677 -- each one appearing to have arisen independently. They named them after birds to make it easier to identify them.
One, called Robin 1, has turned up in more than 30 US states, predominating in the Midwest, they said. A second "first appeared from a Oct 6, 2020 sample from Alabama and is named 'Robin 2' owing to its similarity to the parental Robin 1 sub-lineage," they wrote. It's mainly seen in the Southeast. One called Pelican was first seen in a sample from Oregon, and has since turned up in 12 other states as well as Australia, Denmark, Sweden and India.
Pelican was the first variant that grabbed the attention of the researchers, in part because it was found in nearly 28% of samples from Louisiana and 11% of samples from New Mexico.
"The remaining Q677H sub-lineages each contain around 100 or fewer sequences, and are named: Yellowhammer, detected mostly in the southeast US; Bluebird, mostly in the northeast United States; Quail, mainly in the Southwest and Northeast; and Mockingbird, mainly in the South-central and East coast states," the research team wrote.
The United States has barely studied the genomic sequences of coronaviruses circulating, so if these variants have turned up so often in databases, they are probably very prevalent, the researchers said. The appearance of so many similar mutations at the same time is "remarkable," they said.
"These variants were not detected until mid-August 2020, but as of 03 Feb 2021 already account for over 2,327 of the 102,462 genomes deposited to GISAID from the USA," they wrote. That merits close attention, they said.
This is a crime against humanity!!
People with learning disabilities told they would not be resuscitated if they became ill with COVID-19, says leading charity
https://news.google.com/articl…=en-US&gl=US&ceid=US%3Aen
Charity, Mencap, told The Guardian that many with learning disabilities were told they would not be resuscitated if they got ill from COVID-19 without their or their family's consent in January.
A DNR is a medical order instructing health care providers not to do CPR if a patient stops breathing or heart stops.
Mencap CEO Edel Harris told The Guardian: "Throughout the pandemic, many people with a learning disability have faced shocking discrimination and obstacles to accessing healthcare, with inappropriate Do Not Attempt Cardiopulmonary Resuscitation (DNACPR) notices put on their files and cuts made to their social care support."
According to NHS figures, around 1,220 people with a learning disability have died from coronavirus since February 2020, including 40 of them during the week ending January 29, 2021.
It comes after a Public Health England report from November 2020 found those with learning disabilities had a 6.3 times higher death rate than the general population during the first COVID-19 wave.
Those aged 18 to 34 with learning disabilities aged are 30 times more likely to die of COVID-19 than others their age, the report added.
Harris told The Guardian: "It's unacceptable that within a group of people hit so hard by the pandemic, and who even before Covid died on average over 20 years younger than the general population, many are left feeling scared and wondering why they have been left out."
The Learning Disabilities Mortality Review (LeDer) report revealed that 65% of people with a learning disability who died from coronavirus in the first wave had a mild or moderate one.
Those with a severe or profound learning disability are sixth in line for the vaccine. People with mild or moderate learning disabilities are not prioritized. Mencap has called for this to change.
It estimates that including those with mild or moderate learning disabilities would only be an additional 100,000 to 200,000 people.
The United States has barely studied the genomic sequences of coronaviruses circulating, so if these variants have turned up so often in databases, they are probably very prevalent, the researchers said. The appearance of so many similar mutations at the same time is "remarkable," they said.
Not at all, it's called 'parallel evolution'.
CNN Exclusive: WHO Wuhan mission finds possible signs of wider original outbreak in 2019
https://news.google.com/articl…=en-US&gl=US&ceid=US%3Aen
(CNN)Investigators from the World Health Organization (WHO) looking into the origins of coronavirus in China have discovered signs the outbreak was much wider in Wuhan in December 2019 than previously thought, and are urgently seeking access to hundreds of thousands of blood samples from the city that China has not so far let them examine.
The lead investigator for the WHO mission, Peter Ben Embarek, told CNN in a wide-ranging interview that the mission had found several signs of the more wide-ranging 2019 spread, including establishing for the first time there were over a dozen strains of the virus in Wuhan already in December. The team also had a chance to speak to the first patient Chinese officials said had been infected, an office worker in his 40s, with no travel history of note, reported infected on December 8.
The slow emergence of more detailed data gathered on the WHO's long-awaited trip into China may add to concerns voiced by other scientists studying the origins of the disease that it may have been spreading in China long before its first official emergence in mid-December.
Ben Embarek, who has just returned to Switzerland from Wuhan, told CNN: "The virus was circulating widely in Wuhan in December, which is a new finding."
China seizes on lack of WHO breakthrough in Wuhan to claim coronavirus vindication
The WHO food safety specialist added the team had been presented by Chinese scientists with 174 cases of coronavirus in and around Wuhan in December 2019. Of these 100 had been confirmed by laboratory tests, he said, and another 74 through the clinical diagnosis of the patient's symptoms.
Ben Embarek said it was possible this larger number -- of likely severe cases that had been noticed by Chinese doctors early on -- meant the disease could have hit an estimated 1,000-plus people in Wuhan that December.
"We haven't done any modeling of that since," he said. "But we know ...in big ballpark figures... out of the infected population, about 15% end up severe cases, and the vast majority are mild cases."
Ben Embarek said the mission -- which comprised 17 WHO scientists and 17 Chinese -- had broadened the type of virus genetic material they examined from early coronavirus cases that first December. This allowed them to look at partial genetic samples, rather than just complete ones, he said. As a result, they were able to gather for the first time 13 different genetic sequences of the SARS-COV-2 virus from December 2019. The sequences, if examined with wider patient data in China across 2019, could provide valuable clues about the geography and timing of the outbreak before December.
Ben Embarek said: "Some of them are from the markets... Some of them are not linked to the markets," which includes the Huanan seafood market in Wuhan, thought to have played a role in the virus' first spread. "This is something we found as part of our mission... part of the interaction we had all together."
Variants pose larger questions
Changes in a virus's genetic makeup are common and normally harmless, occurring over time as the disease moves between and reproduces among people or animals. Ben Embarek declined to draw conclusions about what the 13 strains could have meant for the disease's history before December.
But the discovery of so many different possible variants of the virus could suggest it had been circulating for longer than just that month, as some virologists have previously suggested. This genetic material is likely the first physical evidence to emerge internationally to bolster such a theory.
Prof. Edward Holmes, a virologist at the University of Sydney, in Australia, said: "As there was already genetic diversity in SARS-CoV-2 sequences sampled from Wuhan in December 2019, it is likely that the virus was circulating for a while longer than that month alone."
Holmes, who has studied the virus' emergence at length, said these 13 sequences might indicate the virus spread for some time undetected before the December outbreak in Wuhan. "These data fit with other analyses that the virus emerged in the human population earlier than December 2019 and that there was a period of cryptic transmission before it was first detected in the Huanan market."
The WHO team gave a three-hour press conference alongside their Chinese counterparts in Wuhan to present their findings this past week. Since then, more details have slowly emerged as to the precise data they did -- and at times did not -- have access to.
Not at all, it's called 'parallel evolution'.
I like that, but that would indicate an antigen drift, with similar mutations. I think what we see in reality is an antigen shift with the virus finding a new reservoir, probably in domestic animals that have very close human contact. The mutations are to similar to leave it to parallel evolution
Display MoreThis is a crime against humanity!!
People with learning disabilities told they would not be resuscitated if they became ill with COVID-19, says leading charity
https://news.google.com/articl…=en-US&gl=US&ceid=US%3Aen
Charity, Mencap, told The Guardian that many with learning disabilities were told they would not be resuscitated if they got ill from COVID-19 without their or their family's consent in January.
A DNR is a medical order instructing health care providers not to do CPR if a patient stops breathing or heart stops.
Mencap CEO Edel Harris told The Guardian: "Throughout the pandemic, many people with a learning disability have faced shocking discrimination and obstacles to accessing healthcare, with inappropriate Do Not Attempt Cardiopulmonary Resuscitation (DNACPR) notices put on their files and cuts made to their social care support."
According to NHS figures, around 1,220 people with a learning disability have died from coronavirus since February 2020, including 40 of them during the week ending January 29, 2021.
It comes after a Public Health England report from November 2020 found those with learning disabilities had a 6.3 times higher death rate than the general population during the first COVID-19 wave.
Those aged 18 to 34 with learning disabilities aged are 30 times more likely to die of COVID-19 than others their age, the report added.
Harris told The Guardian: "It's unacceptable that within a group of people hit so hard by the pandemic, and who even before Covid died on average over 20 years younger than the general population, many are left feeling scared and wondering why they have been left out."
The Learning Disabilities Mortality Review (LeDer) report revealed that 65% of people with a learning disability who died from coronavirus in the first wave had a mild or moderate one.
Those with a severe or profound learning disability are sixth in line for the vaccine. People with mild or moderate learning disabilities are not prioritized. Mencap has called for this to change.
It estimates that including those with mild or moderate learning disabilities would only be an additional 100,000 to 200,000 people.
think about how evil this is if, these people are neuro-susceptible and this is all being use to create a dialectic - "vaccine equality" - and have society tied in knots over vaccine fairness - to sell us on getting ours.
of course that is what they are doing. The whole scarcity angle is being played on us, and intentionally (see the Paul Offitt interview around 1hr50in)
Good news, latest data from Israel confirm effectiveness of Pfizer’s vaccine:
The basic problem with such data is the current situation. A vaccines efficiency can only be evaluated under normal conditions and when applied to people that do not isolate wearing mask like in care homes.
So comparing unprotected people with mostly protected ones is good marketing of Pfizer. Anyway, the Israel data clearly shows the vaccine induced excess CoV-19 cases/deaths following the first 2 weeks after vaccination. So the data published is from the survivors only as nobody is willing to count vaccination induced deaths as such.
Luckily only Pfizer has this serious problem that already did show up in the phase III study and has been hidden from the public. But in case the vaccine would be given during a silent phase it would indeed work much better.
Consequences: Real/stable data will only be available in 1 year at least. Further,Israel is the worst place to get good data, as the large orthodox community is opposing many measures and has a high infection rate.
Switzerland just reduced the cases by a factor of 8 without vaccination and a soft lock down. The same for Sweden. How the hell will you get stable vaccine success data in a fast changing environment?
