Covid-19 News

    Quote from Wyttenbach

    Mutations so far did not bring any additional risk. Do not believe anything the fear & hate press writes. In Geneva with >80% UK (1.1.7.1) variant the case mortality did go down as already 3 months ago Germans did predict.

    Yes. Actually, since mid-January, after an excess mortality observed in November and December 2020, the mortality rate is now significantly lower here in Geneva than the average of the previous years. And the curve still went down the last week of February with no sign of short-trem inflexion back to "normal" levels. Therefore less mortality is still expected for at least the month of March.


    Epidemiologists didn't expect this "negative excess mortality". Some say it is the result of vaccination. IMHO it is more a natural "negative rebound" after the excess mortality observed in Nov and Dec caused by the death of most fragile people, together with, as you rightly said, a now more prevalent less deadly mutant.

    • Official Post
    Quote from Wyttenbach

    It's as said used in soaps, shampoos. No reason to use it in food.

    There doesn't have to be a reason beyond convenience and profit for manufacturers...


    Foods Containing Propylene Glycol (USA)


    Many foods containing a laundry list of ingredients also contain propylene glycol. Some of the more common packaged foods containing it include dried soups and seasoning blends, marinades and salad dressings and baking mixes for products such as cakes, pancakes and muffins. In the beverage world, soft drinks, flavored teas, powdered drink mixes and alcoholic beverages may also contain propylene glycol. It is also used in some flavoring extracts for baking, as well as in some types of food coloring.


    Propylene glycol is also quite common in fast foods, bread-based products, highly processed snack foods, flavored popcorn and cake frosting. Pre-made, mass-distributed baked desserts such as brownies, cakes and cupcakes may also contain this chemical. Even some ice cream flavors contain propylene glycol.


    Marshmallows, dried coconut shreds and even some cans of nuts contain propylene glycol, as it helps retain an acceptable moisture level in these foods.

    Brazil variant evaded up to 61% of immunity in previous Covid cases


    https://news.google.com/articl…=en-US&gl=US&ceid=US%3Aen


    The coronavirus variant originally found in Manaus in Brazil and detected in six cases in the UK was able to infect 25% to 61% of the people in the Amazonian city who might have expected to be immune after a first bout of Covid, researchers say.


    The extent to which P1 can evade the immune system, and potentially vaccines, emerged as the UK health secretary said the hunt for one person who tested positive for P1 – but did not leave contact details – had narrowed to 379 households in the south-east of England.

    Algorithms Designed to Study Language Can Predict Immune “Escape” Mutations for HIV, Influenza, and SARS-CoV-2


    https://www.genengnews.com/new…influenza-and-sars-cov-2/


    By bridging the conceptual divide between human language and viral evolution, MIT researchers have developed a powerful new computational tool for predicting the mutations that allow viruses to “escape” human immunity or vaccines. Its use could negate the need for high-throughput experimental techniques that are currently employed to identify potential mutations that could allow a virus to escape recognition. The computational model, based on models that were originally developed to analyze language, can predict which sections of viral surface proteins are more likely to mutate in a way that would enable viral escape, and it can also identify sections that are less likely to mutate, which would represent good targets for new vaccines.


    “Viral escape is a big problem,” said Bonnie Berger, PhD, the Simons Professor of Mathematics and head of the Computation and Biology group at the Massachusetts Institute of Technology (MIT) Computer Science and Artificial Intelligence Laboratory. “Viral escape of the surface protein of influenza and the envelope surface protein of HIV are both highly responsible for the fact that we don’t have a universal flu vaccine, nor do we have a vaccine for HIV, both of which cause hundreds of thousands of deaths a year.”


    Berger and colleagues report in Science (“Learning the language of viral evolution and escape”) on their development and use of the computational model to identify possible targets for vaccines against influenza, HIV, and SARS-CoV-2. Berger and Bryan Bryson, PhD, an assistant professor of biological engineering at MIT and a member of the Ragon Institute of MGH, MIT, and Harvard, are senior authors of the paper, and the lead author is MIT graduate student Brian Hie.


    One reason it’s so difficult to produce effective vaccines against some viruses, including influenza and HIV, is that these viruses mutate very rapidly, and this “viral escape” mechanism allows them to evade the antibodies generated by a particular vaccine. Viral escape represents a key obstacle to antiviral and vaccine development, the authors wrote. “Viral mutations that allow an infection to escape from recognition by neutralizing antibodies have prevented the development of a universal antibody-based vaccine for influenza or HIV and are a concern in the development of therapies for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.”

    Therapeutic antibodies, targeting the SARS-CoV-2 spike N-terminal domain, protect lethally infected K18-hACE2 mice


    https://www.biorxiv.org/conten…/2021.02.02.428995v1.full


    Abstract

    Since the onset of the current COVID-19 pandemic, high priority is given to the development of neutralizing antibodies, as a key approach for the design of therapeutic strategies to countermeasure and eradicate the disease. Previously, we reported the development of human therapeutic monoclonal antibodies (mAbs) exhibiting very high protective ability. These mAbs recognize epitopes on the spike receptor binding domain (RBD) of SARS-CoV-2 that is considered to represent the main rout of receptor engagement by the SARS-CoV-2 virus. The recent emergence of viral variants emphasizes the notion that efficient antibody treatments need to rely on mAbs against several distinct key epitopes in order to circumvent the occurrence of therapy escape-mutants. Here we report the isolation and characterization of 12 neutralizing mAbs, identified by screening a phage-display library constructed from lymphatic cells collected from severe COVID-19 patients. The antibodies target three distinct epitopes on the spike N-terminal domain (NTD) of SARS-CoV-2, one of them defining a major site of vulnerability of the virus. Extensive characterization of these mAbs suggests a neutralization mechanism which relies both on amino-acid and N-glycan recognition on the virus, and involvement of receptors other than the hACE2 on the target cell. Two of the selected mAbs, which demonstrated superior neutralization potency in vitro, were further evaluated in vivo, demonstrating their ability to fully protect K18-hACE2 transgenic mice even when administered at low doses and late after infection. The study demonstrates the high potential of the mAbs for therapy of SARS-CoV-2 infection and underlines the possible role of the NTD in mediating infection of host cells via alternative cellular portals other than the canonical ACE2 receptor.

    Quote from Alan Smith

    Many foods containing a laundry list of ingredients also contain propylene glycol.

    Also good Austrian wine contains Glycol's...

    As said: Injecting it is different from eating it! And the real danger is. You can't escape PEG and even the faintest anti-body reaction upon vaccination will finally lead to a disaster.

    off subject but could lead to better understanding of covid spike protein and for future coronavirus vaccines


    A high prevalence of potential HIV elite controllers identified over 30 years in Democratic Republic of Congo


    https://www.thelancet.com/jour…-3964(21)00051-7/fulltext



    Background

    In-depth analysis of the HIV pandemic at its epicenter in the Congo basin has been hampered by 40 years of political unrest and lack of functional public health infrastructure. In recent surveillance studies (2017-18), we found that the prevalence of HIV in Kinshasa, Democratic Republic of Congo (11%) far exceeded previous estimates.

    Methods

    10,457 participants were screened in Kinshasa with rapid tests from 2017-2019. Individuals confirmed as reactive by the Abbott ARCHITECT HIV Ag/Ab Combo assay (n=1968) were measured by the Abbott RealTime HIV-1 viral load assay. Follow up characterization of samples was performed with alternate manufacturer viral load assays, qPCR for additional blood borne viruses, unbiased next generation sequencing, and HIV Western blotting.

    Findings

    Our data suggested the existence of a significant cohort (n=429) of HIV antibody positive/viral load negative individuals. We systematically eliminated collection site bias, sample integrity, and viral genetic diversity as alternative explanations for undetectable viral loads. Mass spectroscopy unexpectedly detected the presence of 3TC antiviral medication in approximately 60% of those tested (209/354), and negative Western blot results indicated false positive serology in 12% (49/404). From the remaining Western blot positives (n=53) and indeterminates (n=31) with reactive Combo and rapid test results, we estimate 2.7-4.3% of infections in DRC to be potential elite controllers. We also analyzed samples from the DRC collected in 1987 and 2001-03, when antiretroviral drugs were not available, and found similarly elevated trends.

    Interpretation

    Viral suppression to undetectable viral loads without therapy occurs infrequently in HIV-1 infected patients around the world. Mining of global data suggests a unique ability to control HIV infection arose early in central Africa and occurs in <1% of founder populations. Identification of this group of elite controllers presents a unique opportunity to study potentially novel genetic mechanisms of viral

    Quote from Fm1

    CDC has had all up to date information on ivermectin as well as the FDA are more concerned with Vaccines then treating the infected and dying.

    That makes no sense. Of course they are concerned with treating the infected! But, if you get vaccinated, you don't get infected. You do not get sick in the first place. Vaccinations are thousands of times cheaper and better than treatment.

    Quote from Fm1

    Had they allowed ivermectin to be used as out patient treatment we would not be seeing MIS-C or long Covid.

    If you are talking about the US, then let me repeat what I have said again, and again, and again:


    Ivermectin is allowed for off-label use. All drugs in the U.S. are allowed for off-label use at the doctor's discretion.


    So, what are you talking about???


    Again:


    IVERMECTIN IS ALLOWED.

    IVERMECTIN IS ALLOWED.

    IVERMECTIN IS ALLOWED.

    IVERMECTIN IS ALLOWED.

    IVERMECTIN IS ALLOWED.

    IVERMECTIN IS ALLOWED.

    IVERMECTIN IS ALLOWED.

    IVERMECTIN IS ALLOWED.


    Do you understand? It is allowed. Your statement "had they allowed" is nonsense. They did. They still do. No one in the U.S. has been stopped. Maybe other countries are different, and maybe you are talking about other countries.

    Again I will ask you, why are US citizens having to use the courts system to get ivermectin treatment if what you say is true? Please explain.

    Quote from Fm1

    Again I will ask you, why are US citizens having to use the courts system to get ivermectin treatment if what you say is true? Please explain.

    let me add a little to this post, vaccination does not, AGAIN VACCINATION DOES NOT prevent you from becoming infected or spread it. It protects against mild to severe disease and why do you think vaccines a cheaper? Someone has to pay for them and when billions go into research, granted through government agencies, who do you think put that money up. The citizens of the united states'. We pay taxes remember.

    Not fully true....


    There is data showing a reduction in virus transmission, meaning vaccinated people - if infected - have a significant lower risk to infect others, compared to non-vaccinated.


    https://www.aamc.org/news-insi…ovid-19-vaccines-debunked

    Myth #2: The vaccines don’t really work that well — they don’t reduce virus transmission.

    "The experts are saying that the vaccines do not reduce transmission, but that is an inaccurate statement,” Gandhi says. “Vaccines have always decreased transmission. What they should be saying is that the clinical trials were not designed to test for asymptomatic infection, but there is every biological reason in the world to believe that they will reduce asymptomatic transmission.”

    There is every biological reason to suggest that many people walking around with partial antibody responses or immunocomprimise will allow vaccine escape (in the weeks after vaccination).


    There is every biological reason to suggest that antibody dependent enhancement will allow the vaccinated to get more sick, much faster, for a future coronavirus variant.

    "There is every biological reason to suggest that antibody dependent enhancement will allow the vaccinated to get more sick, much faster, for a future coronavirus variant."


    Sure - but you should look at the big picture....we had / have hundred millions of infected people, many died. But there is every reason to expect hundreds of thousands or millions less sick and dead people after vaccination than without. Using Ivermectin or other treatments is a different story.

    Quote from zorud

    "There is every biological reason to suggest that antibody dependent enhancement will allow the vaccinated to get more sick, much faster, for a future coronavirus variant."


    Sure - but you should look at the big picture....we had / have hundred millions of infected people, many died. But there is every reason to expect hundreds of thousands or millions less sick and dead people after vaccination than without. Using Ivermectin or other treatments is a different story.

    Take this to the bank: people don't die because of virus, they die of compromised or poor immune systems. Many people who are statistics had no Covid infection, just +ve (broken test).


    The big picture is a scam is happening and the very people susceptible to an infection are susceptible to a vaccine.

    Quote from Fm1

    A high prevalence of potential HIV elite controllers identified over 30 years in Democratic Republic of Congo

    After CoV-19 vaccination you will very likely be tested AIDS positive....

    Quote from JedRothwell

    That makes no sense. Of course they are concerned with treating the infected! But, if you get vaccinated, you don't get infected.

    Vaccines cost 100..500x of ivermectin. Why should I pay more for less??

    Quote from zorud

    Vaccines have always decreased transmission.

    Quote from Navid

    The big picture is a scam is happening and the very people susceptible to an infection are susceptible to a vaccine.

    Then actual picture is that overall the transmission is reduced by a factor of 4. But the most deadly spreaders are already dead... so the effect might be underestimated.

    But even 1/4 is far to much in the German lock down situation if e.g. you sleep along your wive that brought it into the house. Especially if she got 1.1.7.1 then the factor is only 2.


    The real (social) danger in my view is the eugenic drive in politics, that want to give a pass to genetic enhanced individuals without any backing reason/justification. Just as a reward for blindly following the big fat guys rules of the game.


    Ivermectin cures even >90% of the people that must go to ICU. It gives a 100% protection against infection and there will be no spreading of virus with ivermectin as it blocks the viral replication.

    Ivermectin and vaccine


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    Quote from Navid

    Take this to the bank: people don't die because of virus, they die of compromised or poor immune systems. Many people who are statistics had no Covid infection, just +ve (broken test).


    The big picture is a scam is happening and the very people susceptible to an infection are susceptible to a vaccine.

    Seems you totally ignore the 500000 deaths in US alone, who died because of a big scam?? Are you sure they would still be alive without this intrusion from China? Or they would have died because of a compromised immune system or their obesity? :/

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