Covid-19 News

Comparable neutralization of SARS-CoV-2 Delta AY.1 and Delta in individuals sera vaccinated with BBV152

Comparable neutralization of SARS-CoV-2 Delta AY.1 and Delta in individuals sera vaccinated with BBV152

The recent emergence of the SARS-CoV-2 Variant of Concern, B.1.617.2 (Delta) variant and its high transmissibility has led to the second wave in India. BBV152,…

www.biorxiv.org

Abstract

The recent emergence of the SARS-CoV-2 Variant of Concern, B.1.617.2 (Delta) variant and its high transmissibility has led to the second wave in India. BBV152, a whole-virion inactivated SARS-CoV-2 vaccine used for mass immunization in India, showed a 65.2% protection against the Delta variant in a double-blind, randomized, multicentre, phase 3 clinical trial. Subsequently, Delta has been further mutated to Delta AY.1, AY.2, and AY.3. Of these, AY.1 variant was first detected in India in April 2021 and subsequently from twenty other countries as well. Here, we have evaluated the IgG antibody titer and neutralizing potential of sera of COVID-19 naive individual’s full doses of BBV152 vaccine, COVID-19 recovered cases with full dose vaccines and breakthrough cases post-immunization BBV152 vaccines against Delta, Delta AY.1 and B.1.617.3. A reduction in neutralizing activity was observed with the COVID-19 naive individuals full vaccinated (1.3, 1.5, 1.9-fold), COVID-19 recovered cases with full BBV152 immunization (2.5, 3.5, 3.8-fold) and breakthrough cases post-immunization (1.9, 2.8, 3.5-fold) against Delta, Delta AY.1 and B.1.617.3 respectively compared to B.1 variant. A minor reduction was observed in the neutralizing antibody titer in COVID-19 recovered cases full BBV152 vaccinated and post immunized infected cases compared to COVID-19 naive vaccinated individuals. However, with the observed high titers, the sera of individuals belonging to all the aforementioned groups they would still neutralize the Delta, Delta AY.1 and B.1.617.3 variants effectively.

Too Many Coincidences: The Likelihood That a Lab Leak in Wuhan Led to the COVID-19 Outbreak

Too Many Coincidences: The Likelihood That a Lab Leak in Wuhan Led to the COVID-19 Outbreak

BESA Center Perspectives Paper No. 2,112, August 3, 2021EXECUTIVE SUMMARY: More than a year and a half after the outbreak of the COVID-19 pandemic, the way in…

besacenter.org

BESA Center Perspectives Paper No. 2,112, August 3, 2021

EXECUTIVE SUMMARY: More than a year and a half after the outbreak of the COVID-19 pandemic, the way in which its causative virus first emanated remains unclear. While new viruses appearing within humans usually derive from animal viruses, a series of exceptional coincidences in Wuhan, China prior to and during the onset of the pandemic strongly support the laboratory leak theory.

In principle, when a new virus appears in humans that has a genomic similarity to a virus existing in non-laboratory animals, it is plausible to assume that it originated from those animals. This absolutely applies to coronaviruses, and it is for this reason that SARS-CoV-2 was widely postulated to have emerged that way as well.

All that needs to be done to confirm such a hypothesis is to locate the concrete mechanism and conditions that enabled the emergence of the human virus. This kind of a priori approach inevitably endows the natural contagion theory with supremacy over any alternative unnatural contagion concept.

But in the case of SARS-CoV-2, its numerous particularities are such that other possibilities ought to be investigated independently of (and in parallel with) the natural contagion theory. In practical terms, this means that as long as there is no indisputable proof of natural contagion, the unnatural contagion theory—primarily, in this case, the theory of a lab-derived contagion—has to be pursued and soberly evaluated, regardless of any intermediary findings that are published in support of the natural contagion theory.

Such intermediary findings do not in any way affect the intrinsic rationale and likelihood of the unnatural contagion theory. Even if the scientific credibility of the natural contagion idea seems to increase at times, this has nothing to do with the possible validity of an unnatural contagion. Such a possibility in the case of SARS-CoV-2 is wholly autonomous, residing within the intelligence sphere as well as the scientific sphere. The two concepts are not just contradictory in terms of content; they are distinct from one other in both substance and essence.

The possibility that SARS-CoV-2 originated in an unnatural contagion stems from a series of exceptional coincidental events that preceded its emergence in Wuhan, China in 2019. In combination, these multiple convergent coincidences take on a weighty complexity. In other words, there is more to be understood than the fact of the coincidences themselves. Their clustering, just prior to and during the emergence of the virus, is highly suggestive unto itself and should be tackled thoroughly.

Here are some of these coincidental events:

The Wuhan Institute of Virology (WIV) is affiliated with the Chinese Academy of Sciences. Shortly after the pandemic started in Wuhan, Maj. Gen. Prof. Wei Chen, a prominent Chinese biological warfare expert affiliated with the military’s Beijing Institute of Biotechnology, was appointed head of the WIV P4 biosafety level (the highest biosafety level) wing, where various SARS-like viruses are held.

The P4 biosafety level wing was constructed under the supervision of a knowledgeable French company. China arbitrarily put an end to the collaboration with the French when construction was completed in 2017.

The year 2017 also prefigured an upgrade and increased momentum within the scientific sphere at WIV regarding SARS-like coronaviruses. That year, a PhD thesis was completed at WIV on the “Reverse genetic system of bat SARS-like coronaviruses and function of ORFX,” one main achievement of which was the establishment of “a scheme to replace the S (spike) gene without traces.”

The Wuhan Institute of Biological Products has worked with SARS-like viruses at its National Engineering Technology Research Center for Combined Vaccines, in collaboration with WIV, since 2017, and continuing into 2019. During the period of the construction of the WIV P4 wing, the center was relocated 200 meters away from it. The two facilities essentially became one.

On February 24, 2020, a patent for a vaccine against SARS-CoV-2 was filed by principal investigator Yusen Zhou, a PLA (People’s Liberation Army) scientist who worked on it with WIV. Zhou died three months later in undisclosed circumstances.

SARS-CoV-2was found extensively pre-adapted to humans (especially in terms of transmissibility) from the beginning of the pandemic. Specific gain of function experimentation potentially leading to a comparable pre-adapted virus was attempted and mastered at WIV in recent years, including 2019.

A primordial, naturally man-adapted SARS-resembling virus was transmitted from bats to humans in 2012, infecting and killing miners in southwest China. That virus was subsequently “adopted” by WIV, together with related viruses isolated from the same mine. The identity and fate of those viruses have been blurred, despite the fact that they were examined and experimented on up to 2019.

Months before the declared COVID-19 outbreak, the WIV P4 wing requested bids for major renovations to air safety and waste treatment systems in research facilities that had been operational for less than two years.

On September 12, 2019, a vital database regarding viruses collected by WIV was removed from the institute. The removal was explained (much later) by a WIV senior scientist as a step taken “during the COVID-19 pandemic… to prevent cyber security attacks.”

Chinese authorities claim that Patient Zero (the first infected person of the pandemic) appeared in Wuhan on December 8, 2019—yet intelligence reports and scientific findings point to some time between early October to mid-November 2019 as the real onset of the pandemic.

This partial list of coincidences should be evaluated in the context of the January 2021 US State Department Fact Sheet, which discussed a covert collaboration between WIV and the PLA that has been ongoing since at least 2017. According to the Fact Sheet, this collaboration “includ[ed] laboratory animal experiments” (i.e., mice with “humanized” lungs). During this period, WIV was supplied with rhesus monkeys from the Macaque Breeding Base in Suizhou City.

The full list of peculiar coincidences is much longer than what is listed here. The rest pertain largely to the intelligence sphere. They comprise informational (including open source) intelligence as well as estimative intelligence. The volume and substance of classified informational intelligence pertaining to the emergence of SARS-CoV-2 are mostly unknown, at least for the time being.

Estimative intelligence might prove an essential, perhaps even crucial tool for deciphering and confirming the explanation for this remarkable clustering of events. However, we can also make common sense deductions based on circumstantial evidence. Sound deductions often serve, in fact, as force multipliers that can amplify the validity of conclusions reached by intelligence estimates.

There appears to be one logical way to comprehensively explain the described clustering of coincidences prior to and during the outbreak of the global COVID-19 pandemic: a lab leak from China’s WIV. A variety of other peculiar coincidences concerning WIV that have been published in recent months accord with the same logic.

Brett Giroir, a former four-star admiral in the US Public Health Service Commissioned Corps, said: “I believe it’s just too much of a coincidence that a worldwide pandemic caused by a novel bat coronavirus that cannot be found in nature started just a few miles away from a secretive laboratory doing potentially dangerous research on bat coronaviruses. Sometimes, the most obvious explanation is indeed the correct one.”

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Lt. Col. (res.) Dr. Dany Shoham, a microbiologist and an expert on chemical and biological warfare in the Middle East, is a senior research associate at the Begin-Sadat Center for Strategic Studies. He is a former senior intelligence analyst in the IDF and the Israeli Defense Ministry.

Stem-Cell-Like Immune Memory T Cells Present Ten Months After COVID-19 Recovery

Stem-Cell-Like Immune Memory T Cells Present Ten Months After COVID-19 Recovery

A new study from Nature Communications, along with a related piece from Korea Biomedical Review, supports the notion that key

trialsitenews.com

A new study from Nature Communications, along with a related piece from Korea Biomedical Review, supports the notion that key regenerative immune cells are present ten months after infection. The research team determined that the immune memory T cells created during COVID-19 recovery keep working even ten months later. According to the researchers, this is the first study on the stem-cell-like memory cells that folks have after a case of the disease. Shin Eui-Cheol of the Korea Advanced Institute of Science and Technology (KAIST) Graduate School of Medical Science and Engineering, Choi Won-Seok of the Korean University Ansan Hospital, and Jung Hye-Won from Chungbuk National University Hospital headed the research. “Although the memory T-cells cannot prevent infection itself, research has found that it prevents severe progression,” the group said.

While many experts think that “memory T-cells and neutralizing antibodies are the core of protective immunity against Covid-19.” They found that memory T cells were maintained in most recovered folks, even those who had minor cases. Key, when these cells come into contact with the antigen of SARS-CoV-2, “multiply and activate protective immune functions and activate multifunctional T cells simultaneously.” Professor Shin opined, “As the world’s longest-running study of memory T cell function and characteristics in patients recovering from COVID-19, the study is meaningful in that it has laid the foundation for designing a next-generation vaccine development strategy through time-dependent protective immunity analysis.” The team plans to follow-up on those who have been vaccinated and compare the respective immune responses. The paper under discussion is titled, “SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells,” and it is available at the above link.

SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells

SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells - Nature Communications

T cells are instrumental to protective immune responses against SARS-CoV-2, the pathogen responsible for the COVID-19 pandemic. Here the authors show that, in…

www.nature.com

Analysis of the efficacy of early treatments for COVID-19. Treatments do not replace vaccines and other measures. All practical, effective, and safe means should be used. Elimination of COVID-19 is a race against viral evolution. No treatment, vaccine, or intervention is 100% available and effective for all current and future variants. Denying the efficacy of any method increases the risk of COVID-19 becoming endemic; and increases mortality, morbidity, and collateral damage.

COVID-19 early treatment: real-time analysis of 782 studies

COVID-19 early treatment: real-time analysis of 782 studies

c19early.com

United States COVID: 36,051,139 Cases and 630,506 Deaths - Worldometer

www.worldometers.info

August 3rd, 2020 : Daily 57,921 cases No vaccine. Prior administration being blamed for everything by some here.

August 3rd, 2021 : Daily 104,758 cases. Vaccine for 7 months. Current administration cannot be at fault!

And now more mandates coming down the road, for both jabless and vaccinated alike!

And the "science" gap grows even wider.

Quote from Bob#2

August 3rd, 2021 : Daily 104,758 cases. Vaccine for 7 months. Current administration cannot be at fault!

That makes no sense. The administration is not at fault. People who refuse to get vaccinated are at fault. Politicians and right-wing journalists who tell people not to get vaccinated are at fault. If everyone would do what the Biden administration asks them to do, the pandemic would end in a month.

Quote from Bob#2

And the "science" gap grows even wider.

There is no gap. The virus is evolving and mutating, because so many people are infected. The facts are changing. Science is keeping up with it. It is mutating rapidly because so many people refuse to get vaccinated. They are endangering themselves and everyone else.

Quote from Fm1

Israeli has embarked on a third booster program given what’s been going on here, with growing numbers of breakthrough infections, infectious vaccinated persons, and waning effectiveness against the Delta var

This will not help much but introduce very serious risks as this procedure is 100% untested.

Best would be to infect these folks with delta and give them very early Ivermectin.

But Pfizer did raise prices for 25% what will make some Israeli even more rich....

Quote from Fm1

SARS-CoV-2 Lambda, a new variant of interest, is now spreading in some South American countries;

Seems to be just a little behind Delta. So we must watch carefully and may be catch delta first...

Switzerland still sees no real trend in ICU/Deaths but weather is colder since 3 weeks what lets people stay more indoors. So here delta is absolute no problem. Same for UK CFR of known cases: CH 0.1% UK 0.12%. But hidden cases usually are 4..8 fold.

Quote from Bob#2

And the "science" gap grows even wider.

Its not the 'science' gap thats growing.

Quote from JedRothwell

Science is keeping up with it.

These CoV-19 RNA gen therapy pseudo vaccines are not about science. It's about quick and dirty big money. The first real good vaccines just shine up.

Nobody with the slightest understanding of the human immune system would intentionally produce ACE-2 locks as the sole antibody. This simply is a criminal act and should be punished.

Quote from JedRothwell

If everyone would do what the Biden administration asks them to do, the pandemic would end in a month.

Pure BS and rhetoric!

How about Israel? Pandemic ending in a month there? (Only the highest per capita vaccinated)

How about Japan? No spectators at the Olympics.... pandemic ending in a month there? (One of the most regimented societies.) So what is Biden asking that Japan is not?

How about S. Korea? Your "they are doing it right" model. Yes, they do have much lower cases but the pandemic certainly is not over in a month there either! So what is Biden asking that S. Korea is not?

Again, what is Biden asking that will end the pandemic? Do not wear masks (just 2 months ago)... oh wait... wear masks now!.... Exactly WHAT is he asking that was not done before? Other than vaccines being totally available now when none was available before. So please inform me what is Biden asking that will stop the pandemic in one month! Pure BS.

If this was the prior administration, you would be posting daily about how every bit of this surge is 100% Trump's fault and the administration is intentionally killing people. Yet, a different administration with just as bad results is blameless. Typical Cuomo / CNN logic!

So the above statement is pure rhetoric, baseless and political.

Yes, the virus is mutating. The current vaccines are not going to stop it. (see Israel, see everywhere) The vaccines will keep mutating. BS about administration's ability to stop it is simply political rhetoric. NO country is stopping it Science will need to implement another strategy if this pandemic is ever going to be over.... possibly a combination of early treatment and vaccine.

Quote from Zeus46

Its not the 'science' gap thats growing.

Most deaths were seen in New York, New Jersey,Massachusetts. These three states killed their vulnerable already in the first wave without political tactics ?! ...

I would look why there are more deaths in the south! Mexico native, black native genes with high obesity low V-D3.

In General we see. Bad live style, less income, more north more CoV-19 deaths.

Quote from Fm1

SARS-CoV-2-specific T cell memory is sustained in COVID-19 convalescent patients for 10 months with successful development of stem cell-like memory T cells

The paper shows why an infection, even a faint one, is much better and longer lasting protecting that all current vaccines.

Quote by Wyttenbach…

„Best would be to infect these folks with delta and give them very early Ivermectin.„

Is there any evidence that early IVM treatment after an intentional infection will end up with the wanted full (?) naturally developed immunity for those folks? Treating an infection early or take IVM prophylaxis would probably not initiate a natural immunity reaction like recovering from a Corona infection without any treatment? Maybe someone can comment on this, ideally with some links to publications.

Quote from Bob#2

How about Israel? Pandemic ending in a month there? (Only the highest per capita vaccinated)

It will, as soon as they administer the second booster shot. Deaths and most hospitalization has ended. COVID is now no more dangerous in Israel than seasonal influenza.

Quote from Bob#2

How about Japan? No spectators at the Olympics.... pandemic ending in a month there?

It will end when a large fraction of the population is vaccinated. At present only 41% is. Deaths and hospitalizations have already plummeted, because they vaccinated elderly people first. 5 to 10 people are dying per day. That is not a significant problem in nation with 126 million people. It is ~25 times less than the U.S., per capita.

Quote from Bob#2

(One of the most regimented societies.)

It does not seem regimented to me. Society is uncoordinated and uncooperative. You cannot get people to do what is best for society as a whole. Things like tax evasion are widespread. Things like building codes are often ignored in ways the would shock the U.S. public. (See the 2005 Aneha scandal https://www.japantimes.co.jp/n…-as-just-part-of-problem/) It has always been that way. When they introduced electricity, they couldn't even agree whether to make it 50 or 60 Hz, so they ended up with both. The whole country is divided in two. 50 Hz in the east, 60 Hz in the west. During WWII it is said that the Army made more effort to keep secrets from the Navy than from the United States.

Quote from Bob#2

So the above statement is pure rhetoric, baseless and political.

Yes, the virus is mutating. The current vaccines are not going to stop it. (see Israel, see everywhere) The vaccines will keep mutating. BS about administration's ability to stop it is simply political rhetoric. NO country is stopping it Science will need to implement another strategy if this pandemic is ever going to be over.... possibly a combination of early treatment and vaccine.

Bob - I can see that you are unhappy about this virus.

I sympathise.

You are pointing out that the vaccine will not stop the virus. That is true. Most likely nothing will. If you talk to the scientists (the consensus ones the current US administration is not rubbishing) they will say:

(1) most likely - like Flu (for which we also have vaccines) it will end up endemic, serious for a few (but with good protection from vaccines) coming back from time to time. New vaccines will be needed probably every year. No threat to health systems or need to lockdown as long as everyone at risk gets vaccinated. Till then, the need to keep infection rates low is strong. Another problem with high infection rates is the chances of newer variants cropping up quickly increase. We need to keep hospitalisation low enough - from vaccines and previous infection - that health systems stay OK.

(2) possible, less likely, newer vaccines (yes - all of the vaccines currently being release were a 1st do it as quick as possible attempt), will knock it out completely in countries with high vaccination rates (like measles). In that case countries that are not vaccine hesitant will be completely free of it, others will have it endemic at a lowish rate (because even without vaccines eventually all adults will have natural immunity which will work partially against new variants).

(3) possible, but less likely. It will mutate to a variant which is much more deadly (like SARS) and and which evades current immunity (vaccine and natural). Anything like this, and we will go through a year of major hell, whetehr countries decide to lock down or accept 10% death rate. This is the one I really really hope does not happen. I don't think it is that likely, but it cannot be ruled out. A mild version of it (e.g. a new variant which is a bit more deadly and evades the current vaccines quite well) would cause a lot of alarm, death and disruption, but get stomped on by new vaccines within 6 months.

If you put together these options you can see that getting high vaccination rates everywhere now is strongly desirable. It does not remove the threat, but it reduces it. A lot. Both personally (for anyone where vaccine risk < COVID risk) and for society.

As for personal risk. The UK regulators are risk averse. They are now recommending Pfizer vaccine for 16-17 year olds. Anyone over 16 who avoids vaccine is making a personal mistake on balance of risks as well as contributing to a poorer outcome for everyone as in (1),(2),(3) above.

New news - long COVID for 5 - 16 year olds is reassuringly low. 1.8% symptoms persist after 8 weeks.

It would not reassure me, because that is at 18,000 per 1,000,000 level. With vaccine risks of anything < 100 : 1,000,000, and risks of anything serious long term < 10 : 1,000,000, and risks of death < 1:1,000,000 anyone looking at figures should worry more about long COVID unknown risks than vaccine risks.

In this risk equation the one thing less clear is personal risk getting vaccinated after getting COVID. In that case COVID risks are much lower. Much better for society to increase protection with vaccination. Individually I'd guess most young people who understand how small the vaccine risks are would prefer to be vaccinated, but there is no longer such a clear case for it. And even for society we are better off with a population that has natural immunity than with no immunity.

The Future

I am actually extremely hopeful about our future response to these nasty viruses? Why? The COVID vaccines worked really well - and that is largely because our vaccine tech - mRNA - has got better. It will go on getting better. As will the possibility of genetic engineered drug treatments (nose sprays or whatever). understanding of the immune system is the one big medical advance we are in the process of making which will unlock both better vaccines and drugs. I'd hope no-one here sees any in principle difference between the two. Vaccines are the only thing that can (if lucky) eradicate new viruses, but better drugs and vaccines can both help control it.

That is absolutely needed, because modern society with larger population living with animals, significant contact with diverse wild animal species, global mixing, leaves us very very vulnerable to something like COVID but worse.

The one thing that makes me worry is the modern rejection of expert medical advice. Should vaccine hesitancy get really high the next time we have something nasty it might take very large disruption and death toll to change popular opinion enough for people to accept technological solutions to this (technological - too many people travelling too much) problem.

Vaccines vs drugs (now)

There seems to be a misunderstanding about vaccines. The current vaccines (against delta) provide something like a reduction of mortality and hospitalisation to 10% or better of what it would be without them. those figures are much better than expected for any anti-viral drugs.

There is every reason to think that can be kept up against new variants by producing altered vaccine boosters.

Whereas the progress with drugs has been much slower. We do not yet know how to magically make drugs effective against new viruses (whereas we do know how to do that for vaccines).

So saying "vaccines don't work, we need drugs" is being pessimistic. "vaccines don't work, we need better vaccines" is at least something we know we can do - it is only not being done because the current vaccines are still good enough.

It would be great to have drugs as well

Quote from JedRothwell

It will, as soon as they administer the second booster shot.

They may need to re-engineer the booster to cover the Delta virus. Fortunately, mRNA vaccines can be re-engineered quickly. Perhaps within weeks or a few months, according to Pfizer. That's another wonderful thing about mRNA vaccines.

The present vaccine prevents nearly all serious cases and deaths from Delta, but it is not as good at preventing breakthrough infections.

Quote from Wyttenbach

The paper shows why an infection, even a faint one, is much better and longer lasting protecting that all current vaccines.

Do mRNA-based COVID-19 vaccines induce memory T cell response similar to natural infection?

A team of scientists from the United States has recently compared the epitope-specific T cell response after natural severe acute respiratory syndrome…

www.news-medical.net

Six epitopes from the spike protein and 12 epitopes from non-spike proteins were selected to measure T cell responses. The comparison of T cell response after infection or vaccination revealed no significant difference in magnitudes of response, memory phenotypes, T cell receptor repertoire diversity, and αβ T cell receptor sequence motifs in memory T cells generated by natural SARS-CoV-2 infection and vaccination. These findings indicate that the BNT162b2 is capable of boosting pre-existing vaccine-induced as well as infection-induced immunity after the prime-boost immunization.

and...

Clinical and immunological assessment of asymptomatic SARS-CoV-2 infections - Nature Medicine

A cohort of asymptomatic patients infected with SARS-CoV-2 had significantly lower levels of virus-specific IgG antibodies compared to a cohort of age- and…

www.nature.com

Forty percent of asymptomatic individuals became seronegative and 12.9% of the symptomatic group became negative for IgG in the early convalescent phase. In addition, asymptomatic individuals exhibited lower levels of 18 pro- and anti-inflammatory cytokines. These data suggest that asymptomatic individuals had a weaker immune response to SARS-CoV-2 infection. The reduction in IgG and neutralizing antibody levels in the early convalescent phase might have implications for immunity strategy and serological surveys.

So the strategy deliberately infecting people (mildly) to obtain strong "natural immunity" is to make sure people have a fairly severe case of COVID - enough fully to push up immunity, but not so much as to give them long COVID or kill them. That is pretty difficult?

Luckily - vaccines do the job just as well.

Quote from JedRothwell

but it is not as good at preventing breakthrough infections.

Looking at the case rates in the UK, you can see they are very very low in population cohorts that are 90% vaccinated or more. It seems likely that breakthrough infections of delta would still control infections, without lockdown, if we could get child vaccination at high rates, even with current vaccines. Lambda? I don't know.

Unfortunately that does not look feasible yet:

(1) COVID has age-related risk, so authorities are reluctant about allowing them for young children given the small personal risk

(2) Social media and politics has made a toxic combination where significant segments or the population do not trust anything they are told by scientists. A 1% of scientists who disagree will be enough to paralyse 30% of the population. Trying to get > 99% agreement by scientists on anything with a political element is impossible, it always has been. It is just that now the 1% can sway opinion if used by powerful political influencers.

Quote from THHuxleynew

Social media and politics has made a toxic combination where significant segments or the population do not trust anything they are told by scientists

No! We don't trust big pharma marketing. True scientists all do warn the healthy younger age < 65 from taking the RNA gen therapy. Why do you believe that all the old science guard of Pfizer is warning from the younger greedy management??

Real vaccines soon will be on the market. This will change things quite a lot.

Keep in mind that the Pfizer boosters do not improve your immunity = T-cell memory cells. You just get an other 5 months immune deficiency thanks to the ramped up ACE-2 looks antibodies...

These fake vaccines are a business model targeting the fearful old and other fools that did believe in the fairy tales vaccine passports...

Look at Israel "fully vaccinated" within six week (Start 14th June) from 0 to 4000 cases....

Sweden: From 600 cases to 600....not so fully vaccinated... or

Uttar Pradesh: goes down to 30/205mio cases despite no vaccines & Delta. (would be "0" for Israel)