Covid-19 News

    Quote from THHuxleynew

    >The UK regulators are doing a best effort personal risk comparison, and they go down to age 12 quite happily, but say the (health) personal benefits are not clear at age 12.


    >One more thing: the UK decision here was based on medicine and did not consider indirect benefits: less time isolating off school, less chance of infecting carers who might be worse affected, and this in turn could affect the life chances of the child, those ar valid extra considerations.

    IIRC the UK government assessment said that the medical benefits (personal risk/benefit assessment) for 12-16 year olds was marginal (agree that this assessment may change as more data comes in). The decision to facilitate/offer vaccination of this group was therefore primarily justified by those other indirect considerations. I don't see the Government/media pushing hard for vaccination of this group at the moment. I think this may end up being driven more by travel (holiday) rules - though various country travel rules vary and would be good to have global agreement on them.

    Had my 3rd booster jab today - the first 2 were AZ 6 months ago, the 3rd was Pfizer. Guy who jabbed me was a very nice and affable retired GP, warned me of the very slight risk of myocarditis and told me to watch out for chest pains etc, though said that I was too old to be in the highest risk category for that problem


    3 hours ago, and I'm still alive.

    Quote from Alan Smith

    Had my 3rd booster jab today - the first 2 were AZ 6 months ago, the 3rd was Pfizer. Guy who jabbed me was a very nice and affable retired GP, warned me of the very slight risk of myocarditis and told me to watch out for chest pains etc, though said that I was too old to be in the highest risk category for that problem


    3 hours ago, and I'm still alive.

    Great! Are you now magnetic too?

    Quote from JedRothwell

    A "common" problem meaning it happened to 2 people in Japan out of 170,282,260 doses. I do not think "common" means what you think it means. You antivaxxers tend to hijack words to mean whatever the hell you want. L

    Nop, also an issue in Europe (Germany!) The RKI ("Robert Koch Institute") seems not looking close enough.



    "...You antivaxxers tend to hijack words to mean whatever the hell you want. ..."


    AND PLEASE STOP THIS DIFAMATION!

    I am a concerend citizen and a father of two children!! There seem to some major issues with this type of vaccine and the authorities close their eyes and are not taking their responsibility as they should.
    If I sign the vaccinitation approval sheet, it is my own fault, if something goes wrong. This is rediculous!!

    Being a concerned citizen is exactly what now defines anti Vaxer. No questions no concern or you are an anti Vaxer. The true stupidity of members here here yelling anti Vaxer is that most of us have been vaccinated. We took the jab on a leap of faith with the understanding that no infection, no transmitting no hospital and no death, right jed, you claimed that many many times and none is true, but we show concern and jed and Thomas call us anti vaxers . They are the true death cult since the two love labeling other members

    Quote from JedRothwell

    You antivaxxers tend to hijack words to mean whatever the hell you want. Like Humpty Dumpty:


    So true... check out this fine example of word hijacking from our friend Gerold.


    Post
    RE: Covid-19 News
    […]


    Good one Gerold! We all know that if being impolite was an olympic sport, Switzerland would be top of the table...

    Interesting link though, thanks. I'm not sure it really helps the argument that covid vaccines are dangerous though. No one is doubting that >100 Swiss people died after being vaccinated. Its just unlikely it was that vaccine that killed them.

    Translated:
    The [Austrian] Federal Office for Health Safety (BASG) reported 151 deaths close to a vaccination against COVID-19 (116…
    Zeus46


    PS. I never got an answer to my question...

    Is Molnupiravir a Global Catastrophic Threat?


    Is Molnupiravir a Global Catastrophic Threat?
    Note that views expressed in this opinion article are the writer’s personal views and not necessarily those of TrialSite. Merck’s Molnupiravir (also known
    trialsitenews.com


    Note that views expressed in this opinion article are the writer’s personal views and not necessarily those of TrialSite.


    Merck’s Molnupiravir (also known as EIDD-2801 and MK-4482) is a mutagenic nucleotide analogue [1]. It introduces errors in the SARS-COV-2 RNA at the time of replication after proofreading, and causes lethal mutagenesis [2]. This threatens to accelerate the evolution of the coronavirus.


    Any major variant of the coronavirus represents local optimum (in mutations space), maximizing coronavirus’ fitness. One- or two-point mutations cannot accomplish this. A new variant can only rise through the change of the virus-host-conditions systems, or through larger mutations set. Even a moderate increase in the point mutations frequency causes a big increase in the frequency of multi-point mutations and dangerous recombinations. Such events are too rare to be caught in small trials, but inevitable in large populations, and might lead to catastrophic consequences. The authorization and broad use of Molnupiravir is likely to breed very dangerous SARS-COV-2 variants.


    Assuming a drug causes an N times increase in frequency of non-synonymous mutations (the rate of errors), the frequency of simultaneous mutations in k points would increase by Nk. Apparently, Molnupiravir increases the rate of errors 2.5-3 times for the range of concentration from sub-toxic 1 µM to toxic 10 µM of rNHC [2]. At 3x, that increases the frequency of 4-points mutations by 81x, per replication cycle.


    Additionally, Molnupiravir does not stop coronavirus replication immediately. Multiple replication cycles take place within each host under Molnupiravir. The unfit genomes are eliminated, and the fitter ones (immune escape, higher infectivity etc.) are preferred. This further increases the chances of a large mutation set increasing the virus’ fitness.


    The increase in recombinations is even larger. SARS-COV-2 virions can swap parts of their genomes [3]. Usually, a host gets infected by a single strain, and all genomes are similar, differing by a small number of mutations. Recombination between genomes that differ from that strain’s genome set by 1-2 mutations is not much different than a two-point mutation. Recombination between genomes with large (k>=3) sets of different mutations can be significant. The frequency of recombinations between mutation sets of size k or more increases the proportionally to the square of the frequency of such sets, yielding N2*k. Thus, for k=4, that would yield an increase of more than 6,500 times.


    Population level effects compound these numbers.


    These back-of-the-envelope calculations sharply underestimate the danger because they assume average or median values, rather than probabilities’ distribution tails (i.e., the probability of 10-point mutation is increased 59,000x).


    The current SARS-COV-2 Delta strain (worldwide prevalence > 80%) has 24 mutations. It was sequenced in August-September 2020 [4]. This suggests that SARS-COV-2 already mutates and evolves faster than we thought, and the sudden appearance, persistence, and recombination of sets of 5+ point mutations is a big driver of it. Can we really afford to increase the frequency of such events thousands of times?


    Another possible outcome of broad use of Molnupiravir could be the appearance of SARS-COV-2 strains without proofreading, compensating for that with higher replication rates or other features. The possibility that a coronavirus can do this has been shown in-vitro, on another large RNA virus by disabling its proofreading mechanism [5].


    Broad use of Molnupiravir would likely cause a catastrophic event, such as the emergence of a super-SARS-COV-2, which would evade existing immunity and have an infection fatality rate (IFR) of over 3%. In such a case, the social and infrastructure collapse would kill many more people than would die from the disease.


    Even if the drug had very significant benefits for individual patients, it would not justify such a global risk. Molnupiravir is useless. Even at the advertised 50% effect, it is inferior to Ivermectin.


    Of course, Molnupiravir also causes mutations in human DNA [2] [6], but those consequences (cancer, birth defects etc.) will only present themselves later, and their connection to the drug will be denied. Only one study of Molnupiravir’s side effects had been conducted [7] [8].


    SARS-CoVs were shown to survive and continue to replicate with a 20-fold increase in mutation rate [3]. This casts additional doubts on Molnupiravir’s effectiveness claims. One temporary, slight benefit could be due to the possibility that the current Delta strain already has an increased mutation rate.


    Nevertheless, Dr. Fauci has already promised that the FDA would review Molnupiravir as quickly as possible [9].


    Conclusion

    Among the FDA, NIH, and CDC, Merck is the only adult in the room and should act as such. Given the global, catastrophic risks, the individual safety concerns, and the utter lack of follow-up studies for even as little as 12 months, Merck should not even consider applying for an EUA for Molnupiravir.


    Reference

    1. Gordon CJ, Tchesnokov EP, Schinazi RF, Götte M. Molnupiravir promotes SARS-CoV-2 mutagenesis via the RNA template. Journal of Biological Chemistry . Elsevier; 2021 https://www.jbc.org/article/S0021-9258(21)00563-9/abstract


    2. Zhou S, Hill CS, Sarkar S, et al. β-d-N4-hydroxycytidine Inhibits SARS-CoV-2 Through Lethal Mutagenesis But Is Also Mutagenic To Mammalian Cells. The Journal of Infectious Diseases . 2021 https://doi.org/10.1093/infdis/jiab247


    3. Denison MR, Graham RL, Donaldson EF, Eckerle LD, Baric RS. Coronaviruses. RNA Biology . Taylor & Francis; 2011 https://doi.org/10.4161/rna.8.2.15013


    4. Mullen J, et al. outbreak.info. 2020. https://outbreak.info


    5. Graepel KW, Lu X, Case JB, Sexton NR, Smith EC, Denison MR. Proofreading-Deficient Coronaviruses Adapt for Increased Fitness over Long-Term Passage without Reversion of Exoribonuclease-Inactivating Mutations. mBio . American Society for Microbiology; 2017 https://journals.asm.org/doi/full/10.1128/mBio.01503-17


    6. Zhou S, Hill CS, Woodburn BMD, Schinazi RF, Swanstrom R. Reply to Troth et al. The Journal of Infectious Diseases . 2021 https://doi.org/10.1093/infdis/jiab363


    7. Discontent M. Molnupiravir’s Rush should Remind us to take a Cautionary Approach . Modern Discontent. 2021 https://moderndiscontent.subst…ravirs-rush-should-remind


    8. Discontent M. A Possible Side Effect of Merck’s Oral COVID-19 Drug should alarm the Public . Modern Discontent. 2021 https://moderndiscontent.subst…ble-side-effect-of-mercks


    9. Towey R. Fauci says FDA will review Merck’s new Covid treatment “as quickly as they possibly can” . CNBC. 2021 https://www.cnbc.com/2021/10/0…s-they-possibly-can-.html

    Some more details about why the assumption of > 50% CoV-19 infection in UK is accurate.

    Who can give blood
    Find out more about who is eligible to give blood. You should be able to give blood if you are fit and healthy, weigh over 50kg and are between 17 and 66. Men…
    www.blood.co.uk


    This are the rules for UK blood donors. The average vaccine inclusion week 8 2021 of the people allowed to donate is far below 15%. Further after vaccination you have to wait to donate blood. At week 10 47% had antibodies what defines that at least 35% had contact with CoV-19 until week 8. (It takes 2 week for antibodies to show up!)


    Further:: People with side effects from CoV-19 vaccination have to wait for donation 28 days: https://my.blood.co.uk/Knowled…x/coronavirus%20infection > 50% had side effects.


    So if we take into account that from week 6 on the epidemic was pretty low then week 10 gives the exact picture for week 6 (where we take the PCR+) . This is due to the fact that also people with a CoV-19 infection have to wait 28 days. This further reduces the vaccination impact on the figure.

    So we have 4.1 million PCR+ cases and close to 34 million S-positive with 10% at most from vaccination, what gives the expected silent case rate of 7x (mixed alpha (4), gamma (6), delta (10).

    Remember that the first highly vaccinated group, age > 65 is not among blood donors.


    So we must live we the week 6 (10) data for our estimates that give at least 50% CoV- 19 infection or more real > 60% due to 4 million added delta cases with the highest silent factor that one must halve due to the reduced vulnerable group.

    Fauci Careful with His Words Yet Still Misrepresents That Vaccinated Don’t Spread the Virus


    Fauci Careful with His Words Yet Still Misrepresents That Vaccinated Don’t Spread the Virus
    Dr. Anthony Fauci, Director of the National Institutes of Allergy and Infectious Diseases (NIAID) and chief White House medical advisor, was interviewed
    trialsitenews.com


    Dr. Anthony Fauci, Director of the National Institutes of Allergy and Infectious Diseases (NIAID) and chief White House medical advisor, was interviewed today on Bloomberg Markets and Finance. America’s top doctor was far more careful in what he declared today, knowing the charged environment he operates in—and of course, that many eyes are on him. He was asked a series of questions from discussion of child vaccination to boosters, the mixing and matching of vaccines, and his take on the Merck antiviral Molnupiravir to a parting goodbye to National Institutes of Health (NIH) director Francis Collins. While TrialSite applauds Fauci’s reserved tack (not making any promises about dates—deferring to the U.S. Food and Drug Administration (FDA), the top doctor should know better to declare with so much data now available on waning vaccine effectiveness that the main reason to get the vaccine is to not transmit the disease to others. That’s a misrepresentation of the situation. Vaccination reduces the risk of more serious disease, hospitalization, and death. However, after just a few months with the pervasive Delta variant, there have been many studies of vaccinated populations, such as a recent UCSF-based study, the Mayo Clinic, research out of Israel, or, for that matter, the Department of Defense-backed Project Salus. Those studies indicate that vaccinated populations are experiencing unprecedented breakthrough infections and waning vaccine effectivity, leading to transmission of the virus. We need our public health officials to speak the truth.


    TrialSite observes that when Fauci was asked about vaccinating 5- to-11-year-olds with the Pfizer-BioNTech vaccine, the nation’s top doctor was far more calculated, acknowledging that anything he might say could be taken out of context, interpreted differently, and used as part of a hostile narrative.


    This time, Fauci correctly acknowledged that no group or individual, not him nor POTUS for that matter, can get ahead of the U.S. Food and Drug Administration (FDA) and the regulatory process. When the Bloomberg host asked the doctor if he thought the vaccine could be ready for these elementary age school children by Thanksgiving, for example, Fauci again suggested that the FDA’s Vaccines and Related Biological Products Advisory Committee (VRBPAC) needs to take the time to review the vaccine’s safety, immunogenicity, and efficacy. Fauci suggested that the FDA’s VRBPAC should be meeting within a couple of weeks.


    Fauci went on to discuss boosters and the mixing and matching of vaccines, including BNT162b2 (Pfizer-BioNTech), Moderna, and the Johnson and Johnson vaccine. He noted that the same independent VRBPAC process now unfolds.


    Fauci was asked about people who think they could take an antiviral pill (assuming it eventually passes emergency use authorization or approval) and bypass a vaccine. Fauci emphasized that absolutely is not the case.


    Fauci shared that vaccination was key to stopping viral spread and, hence, the advancement toward herd immunity. The key to his argument is that the vaccinated are missing the virus, which we know is absolutely not the case. With waning effectiveness, there are millions of Americans now vaccinated that are infected, and spreading the virus. The data points to the vaccines reducing the severity of infection and hospitalization, which of course, is a good thing. But TrialSite was surprised Fauci was still making an argument that was reminiscent of some time in 2020.


    VRPAC is looking at data and will meet with the FDA in a couple of weeks. How long will it take? FDA takes this seriously—as carefully and expeditiously as possible. But they have the responsibility of safety and availability, declared Fauci—”You don’t want to get ahead of them.”


    On Boosters et al.

    He suggested that some approvals are in place. What about mixing and maxing—can a J&J vaccine recipient get a booster from Pfizer and Moderna? Fauci again deferred to regulators that will need to review the safety, immunogenicity and efficacy data. Again, the VRBPAC process is key.


    The Merck Antiviral Pill

    Fauci was asked about the recent announcement by Merck that the drug antiviral Molnupiravir could cut hospitalization and death by 50%. Does this threaten the role of the vaccines? What if some people take up the position “Who needs the vaccine if I can take a pill if I am sick?”


    First of all, Fauci clarifies his position on the antiviral vs. vaccine debate. The pill, should it be authorized on an emergency basis or approved, of course, can be used by someone that has been infected with COVID-19 within a few days. Merck did the study as a direct antiviral. The premise is that if someone is exposed to the virus, they can take the pill and reduce the impact of any infection.


    This data was based on a study with about 700+ participants (the data independent data safety monitoring board stopped the study due to positive results). Fauci reported that while only 7% of participants on the study drug met the endpoint, 15% on the placebo met a negative endpoint. Moreover, with no deaths in the study drug cohort, there were eight deaths in the placebo group. He emphasized that this data isn’t reviewed yet by the FDA, and there is a need for bigger studies looking into safety and efficacy.


    Fauci correctly declares that any position presupposing no need for a vaccine due to the Merck antiviral treatment essentially represents a false narrative.


    How concerned is Fauci about future variants?

    There are many variants out there, but it certainly appears like Delta is the dominant one now. Delta is so easily and efficiently transmitted that it has crowded out other variants. As long as you have a virus freely circulating then of course it replicates, giving itself ample opportunity to mutate, which will lead to mutation and new variants, suggests the NIH veteran. Fauci argues that the best way to prevent variants is not to allow the variant to spread.


    To some extent, this is where Fauci uses misinformation. He suggests the nearly 70 million Americans that are not vaccinated should get vaccinated as quickly as possible so that people don’t spread the pathogen to each other anymore. But what about all the studies now showing waning effectiveness and ubiquitous breakthrough infections? He still uses the narrative of nearly a year ago centered on vaccination as a tool to stop viral transmission and achieve herd immunity. But that assumption is shattered by 1) vaccine products that evidence a general waning in effectiveness starting in three months– definitely by month five to six, and 2) stronger variants such as Delta that led to just as large of a viral load in both the vaccinated and unvaccinated. Fauci isn’t being totally honest with the American public in this way.


    Fauci concluded with praise for the soon-to-be resigning NIH director Francis Collins.

    Quote from Nar

    Ivermectin: How false science created a Covid 'miracle' drug

    BBC is a free mason run big pharma trumpet ::


    The BBC can reveal that more than a third of 26 major trials of the drug for use on Covid have serious errors or signs of potential fraud. None of the rest show convincing evidence of ivermectin's effectiveness.


    BBC in fact can show nothing else than words from FM/R public relation campaign and refuses to report about India's success with the Ivermectin campaign...


    Reference CAS-6848484-R4P2F8


    Dear Dr Wyttenbach


    Thanks for getting in touch with us regarding the BBC News website.
    I understand you feel there is not enough coverage into the potential use of Ivermectin as a treatment for covid-19.


    Many stories compete for coverage each day and we select items based on their editorial merit. We look at the significance of each story, the likely level of interest in it and whether the facts it contains are new. However, we strive to be objective and dispassionate in the way we select stories, as we feel this best serves the target audience for the relevant BBC network. We know that not everyone will agree with our choices on which stories to cover. Our news editors make these complex decisions, based on the editorial merit of all the stories at hand. Inevitably, there may be disagreements about the level of prominence we give to stories.


    This is the official answer of BBC (free masons). They obviously willfully violate their own rules to promote their own fake narrative.

    1 billion Indian are free of CoV-19 since 4 months. No other place on the planet can claim this. So this is neither news, nor interesting, nor important for BCC. Why it violates the free masons rule to not cover anything that harms the FM income.


    BBC in fact behaves as fascist supporting media totally inline with the big pharma terror!


    Why do you re-post this fake news? Merck want's to sell Merck-Vectin a drug that 100% failed in the hospital setup. That also failed in the outpatient setup given what BBC claims are failed Ivermectin studies....



    Quote from Fm1

    Dr. Anthony Fauci

    simple equation :: (Anthony Fauci) = (Dr. Menegle)2


    We know since a long time that large groups of WWII fascist do & did hide in USA. It would be no surprise we one could find some in his close circle.

    Further US military, & services (post war) did actively employ several 1000 of the worst Nazi's. Now the question why ? Friends in mind?

    Quote from Alan Smith

    Whereas the UK right wing describe the BBC as a nest of woke communist sympathisers. How confusing.

    Depends on the matter. Fascists (UK) = free masons = money & power. Left = dreams about better future...


    Divide et impera. If not possible construct fake poles do it as long as you can split the population (Brexit, blue/red USA).


    But with CoV-19 BBC supports killing people and this is far over any red line.


    Soon you will see promotion articles, videos for Merck-Vectin on BCC. You could bet on this....

    Switzerland:: Double vaxx deaths update. Since 1. October we had 115 deaths 42 double vaxx so 36% of all death are double vaxx- about 15% (absolute) more since may last report. Total vaccination is around 56% so the double vaxx death protection rate is more or less the same (100-36)%.


    Covid-⁠19 Schweiz | Coronavirus | Dashboard
    Covid-⁠19 Pandemie Schweiz und Liechtenstein: Fallzahlen, Virusvarianten, Hospitalisationen, Re-⁠Wert, Spitalkapazitäten, internationale Lage, Zahlen zu Tests,…
    www.covid19.admin.ch


    We here have Pfiter crap and Moderna. As expected the Pfizer crap death rate is 3x of Moderna. So the protection from double vaxx Pfizer is already more or less gone (< 30%) here too!

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