Covid-19 News

    • Official Post

    Only if we do not collect taxes to pay it down. We can easily fix this. Just return to the Clinton era tax rates and all will be well after while. People were not starving in those years. Grass was not growing on the streets of America. Rich people got a lot richer during those years.


    There is no crisis in the Federal debt, because it can easily be paid down. Gradually, but easily. The only "crisis" is that the 1% does not want to pay taxes, so they end up paying maybe 15% of their income (the capital gains tax rate), or zero if they can hide the money in the Cayman Islands. The top 1% earns 13% of national wealth. The top 10% earns 39%. So they can easily afford to pay more taxes, at least until the debt is retired.


    The phrase "never let a crisis go to waste" comes to mind. As applied to COVID on a national level, it means taking advantage of the turmoil to expand government well beyond what our founding founders envisioned.


    As applied to this forum, it is not the place to sort out the age old debate on the merits of socialism vs capitalism. Which is kinder and gentler, and which is best overall for it's citizens. Big government vs little. It was painful enough that we cracked open the door this one time, to allow *limited* politics, in light of the dire circumstances.


    So tempting as it is, I just can't go there with you. Best we keep this focused on the politics, and science of the COVID, and not stray too far.

  • Food banks are overwhelmed. People are sitting in cars, waiting for hours, and getting nothing:


    ‘Never Seen Anything Like It’: Cars Line Up for Miles at Food Banks

    Millions are flooding a charitable system that was never intended to handle a nationwide crisis.


    https://www.nytimes.com/2020/0…ronavirus-food-banks.html


    This is another example of our political leaders taking a bad situation and making it catastrophic. Because they are blithering idiots. In a country where most people do not have $400 extra for an emergency, you can't tell people to stay home and shelter in place without providing them with food.


    If we are going to have a society where the top 1% elite takes much of the income and nearly all the wealth, and most people don't even have $400 to spare, that 1% better be ready to feed the rest of society in a disaster. Either that, or the elite should be prepared to lose everything to social disruption or inflation. You can't have it both ways.

  • As applied to COVID on a national level, it means taking advantage of the turmoil to expand government well beyond what our founding founders envisioned.

    Frankly, I could not care less what the founding fathers envisioned. They did not live in a world with the internet, AI robots taking jobs, international pandemics, $72,000 hospital stays for one week, or 1% of society taking nearly all the wealth with the help of technology and upside-down tax laws. We must make our society and our economy to fit our present circumstances. Not some ideal of how society was 200 years ago. If government must grow now, let it grow! It can shrink later on. Medical technology will mature, and hospital stays will get cheaper. We will find ways to ensure a basic income. We can solve any problem. But we cannot live in the past, or use methods of government that worked in a world without electricity.


    You will note also that the Founding Fathers plans went badly wrong from 1862 to 1865, resulting in the deaths of 625,000 people, the equivalent of 6 million today. That was a flawed system, to say the least. It was not something we want to return to. It was a nightmare envisioned.

  • As applied to this forum, it is not the place to sort out the age old debate on the merits of socialism vs capitalism. Which is kinder and gentler, and which is best overall for it's citizens.

    The answer seems obvious to me. At present --


    A judicious mixture of the best of socialism and capitalism works best. The two are at odds to some extent, but not completely at odds. In countries such as Sweden they have a better balance, and a higher standard of living.


    In the future --


    Human labor will be worthless, and both capitalism and socialism will cease to exist. Both are economic systems predicated on people trading labor for money. Most people have no source of wealth other than their own labor. When human labor is worth a few pennies per day, no one will buy it or have any use for it. Hiring someone to work in competition with an intelligent robot will be like hiring someone today to add up numbers, when your computer can add more numbers in a second than a person can add up in a lifetime.


    We have to remake the world to fit this upcoming technology. We can, I am sure. If people are clever enough to invent AI robots, we can also invent a way to live with them to everyone's benefit. We have remade the world countless times since people first grasped tools and began to shape the world. We will do that again in the future, many, many times. It is nothing to fear.

  • Sorry if this has been posted before, this thread is flying with comments and is hard to keep up.


    I think this article, which analyses new data on antibody titles and the lack of them in inmunity inducing amounts, in a very significant fraction of Covid-19 sufferers after recovering, is alarming.


    https://www.scmp.com/news/chin…els-raise-questions-about


    I'd like to repeat that antibody titre amount does not necessarily correlate so immaculately to true, functional immunity. We have our cell mediated immunity (like killer cells) and our antibody immunity. These two systems can operate at the expense of the other. It's complicated and varies with the particular pathogen or vaccine. So for instance, in the article you linked, it's the younger people who have the much lower antibody titres after being exposed to the virus. But I bet their cellular immunity is great, and I suspect that for covid19, having a robust cellular immune response is preferred over a high antibody titre, if one had to choose. Older adults making all that antibody are, imo ,compensating for a lack in the preferred cellular immunity response. It will be interesting to see how common reinfection is, and whether it afflicts the older population more.

  • Well, COVID symptoms are not distinguishable easily from other respiratory illnesses, as you know.

    In that case we have a ZFR (Zelenko fatality rate) of 1.3%, or 10/700. BUT that assumes a normal demographic (median age 30 - 40).


    You can relate it to the Swiss figures ( or Norway) as Switzerland is a genetically very mixed nation. at bit more than 1/9 of people with symptoms test positive what would give about 80 cases in Zelenkos case. But it is important to treat people the first 5 days after that you are a severe case. Thus Zelenkos is just one picture that shows how early medication works.

    And also remind that 5% of the tested positive cases (according Swiss figures) either die > 50% or need ventilation. Thus 4 of of 80 would have become severe case with 2-3 dead.

  • You can relate it to the Swiss figures ( or Norway) as Switzerland is a genetically very mixed nation. at bit more than 1/9 of people with symptoms test positive what would give about 80 cases in Zelenkos case. But it is important to treat people the first 5 days after that you are a severe case. Thus Zelenkos is just one picture that shows how early medication works.

    And also remind that 5% of the tested positive cases (according Swiss figures) either die > 50% or need ventilation. Thus 4 of of 80 would have become severe case with 2-3 dead.


    I cannot relate Zelenko's figures to anything unless you have figures for a very young population - median age 15? That information shows why he has such low hospitalisation rate: independently of any treatment.

  • I cannot relate Zelenko's figures to anything unless you have figures for a very young population - median age 15? That information shows why he has such low hospitalisation rate: independently of any treatment.


    Could you clarify : Are you saying that the people Zelenko has treated have a median age of 15?

  • cannot relate Zelenko's figures to anything unless you have figures for a very young population - median age 15?


    We have the figures for median 15. But how did you guess the median age 15 ???


    In the update he is now at 900 patients and Raoult at 1000!!


    The question is always how many will go to ICU as Boris and even worse go to ventilators. About 5% of ICU cases is in the class of 18..65. thats the upper half of your guessed median.

  • Two more 30 yr old nurses dead today from COVID-19 forced to use bin liners as protection. 938 more new deaths in hospitals, countless others in nursing homes. I wonder what all their orphaned children will think of the doctors in the future still refusing to treat patients with HCQ or using it to protect NHS nursing staff? Would they calmly say well there was no evidence for it working was there. After all the evidence we have put forward here, to the BBC to the NHS, to Cuomo, to Trump, to Ferguson?:(

  • A new preprint that may be of interest --

    The IMPDH inhibitor merimepodib suppresses SARS-CoV-2 replication in vitro

    https://www.biorxiv.org/conten…0.04.07.028589v1.full.pdf


    Some flavonoids also inhibit IMPDH --

    Inhibitory Effect of Curcumin on IMP Dehydrogenase, the Target for

    Anticancer and Antiviral Chemotherapy Agents

    https://www.jstage.jst.go.jp/article/bbb/74/1/74_90568/_pdf


    Myricetin is a novel inhibitor of human inosine 5′-monophosphate dehydrogenase with anti-leukemia activity

    https://www.sciencedirect.com/…abs/pii/S0006291X16311123

  • "Vitalstoff.Blog publisher Uwe Alschner in conversation with Professor Wittkowski"


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    "Knut M. Wittkowski was a professor of epidemiology and biostatistics at Rockefeller University in New York for 20 years. He is a proven expert in modeling epidemics. He made his first determination in the 1980s when he denied the danger of an HIV epidemic in the heterosexual population - and kept it right. In the current debate about SARS-CORONA-2, Professor Wittkowski is now declaring, based on data from the registration authorities and on experience with dealing with respiratory diseases, that the epidemic has already peaked."

    • Official Post

    https://www.nature.com/article…39373-98c3a376d1-44567417


    COVID-19 vaccine R&D landscape

    As of 8 April 2020, the global COVID-19 vaccine R&D landscape includes 115 vaccine candidates (Fig. 1), of which 78 are confirmed as active and 37 are unconfirmed (development status cannot be determined from publicly available or proprietary information sources). Of the 78 confirmed active projects, 73 are currently at exploratory or preclinical stages. The most advanced candidates have recently moved into clinical development, including mRNA-1273 from Moderna, Ad5-nCoV from CanSino Biologicals, INO-4800 from Inovio, LV-SMENP-DC and pathogen-specific aAPC from Shenzhen Geno-Immune Medical Institute (Table 1). Numerous other vaccine developers have indicated plans to initiate human testing in 2020.

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