Covid-19 News

Quote from Wyttenbach

[There is a long road, which will end with a vaccine.]

That's dreaming of an UFO that will save the world...

Again let me point out that every single expert, at the W.H.O. the CDC and every other agency, says that a vaccine will be developed. They differ only in how long they think it will take. They express no doubts at all that it is possible.

You say it will not happen. Two questions arise: 1. Why not? 2. Are you such an expert in this subject that you know more than all of these experts at major institutions? Tell us about your qualifications, your research, and the papers you have published.

As I said before, one of the most important lessons of cold fusion is that the experts in a field are usually right, and people outside the field are wrong. Also, amateurs and random Wikipedia editors are wrong. Cold fusion researchers have been portrayed as mavericks, but they are just the opposite. As Fleischmann said, "we are painfully conventional people."

Quote from seven_of_twenty

lowering of fever

inflammation and fever are part of the immune defense...

acetaminophen reduces fever.. ibuprofen reduces both.

in general , they are not useful for combatting a potentially lethal infectious pathogen..

Although I might take one for the annoying sinusitis which I regularly get.. I wouldn't risk them with Covid..

RAPID RESPONSE PIPELINE FOR STABILIZED SUBUNIT VACCINES
Keith Chappell, School of Chemistry and Molecular Bioscience, The University of Queensland Australia
[email protected]

Quote from JedRothwell

a vaccine will be developed.

https://dc.engconfintl.org/cgi…xt=vt_vii&type=additional

Assuming that the UQ Australia lab are one week into mouse trials

34-5 =29 weeks to go..til large scale commercial release of vaccine.

Positive RT-PCR Test Results in Patients Recovered From COVID-19

https://archive.is/TpnNV#selection-3353.0-3353.64

Lan Lan, MD¹; Dan Xu, MD¹; Guangming Ye, MD²; et al Chen Xia, MS³; Shaokang Wang, MS³; Yirong Li, MD, PhD²; Haibo Xu, MD, PhD¹ Author Affiliations |Article Information

• ¹Department of Radiology, Zhongnan Hospital of Wuhan University, Wuhan, China
• ²Department of Laboratory Medicine, Zhongnan Hospital of Wuhan University, Wuhan, China
• ³Beijing Infervision Technology Co Ltd, Beijing, China

JAMA. Published online February 27, 2020. doi:10.1001/jama.2020.2783

oldguy 's link above is truly terrifying:

Quote

Four patients with COVID-19 who met criteria for hospital discharge or discontinuation of quarantine in China (absence of clinical symptoms and radiological abnormalities and 2 negative RT-PCR test results) had positive RT-PCR test results 5 to 13 days later. These findings suggest that at least a proportion of recovered patients still may be virus carriers.

[my emphasis]

Sober but encouraging and well written article about the promise of remdesivir. https://www.statnews.com/2020/…head-against-coronavirus/

Quote

Like a bad song clears out a dance floor, remdesivir can clear the viral levels in a person, as long as it can interrupt enough replication. The key, researchers say, is that it has to be delivered somewhat early in an infection, as the virus is still proliferating. In patients who develop severe disease, it’s not the virus that’s always the main problem. The body’s own immune system can react by heading into overdrive and causing secondary complications like organ damage. An antiviral can’t head that off once it’s begun.

“If you wait to treat someone until they’re in the ICU on a ventilator, it’s too late, you’re not going to do a darn thing,” said Richard Whitley, an infectious disease expert at UAB who coordinates the antiviral consortium.

That, of course, is still just opinion. The work is just getting off the ground but, as the authors note, it may move fairly fast because toxicity and dose studies were already done for ebola.

Quote from JedRothwell

Again let me point out that every single expert, at the W.H.O. the CDC and every other agency, says that a vaccine will be developed.

Yes! This is tried since at least 30 years without success or even worse with strong negative outcome. Never bet on an irrational hope! WHO has to tell this as these guys are a part of the mafia that only likes to make the most money possible.

What do you think they will charge you for a vaccination ??? 1000$ or more like 40'000 as for a Hepatitis cure or 1400$ for a lucent is shot to save you wet macula ????

Quote from Shane D.

Yes, there is a price on our heads! Sounds heartless, but one of those facts of life we are all guilty of, but never admit.

The problem is that a full lung infection leaves behind a live long damaged lung (reduced capacity) in cases of covid-19 as Japanese researchers just published!

Why is Italy hit so hard? Exactly the very same reason as Wuhan. Factor 20X above limit smog almost same for north west Germany where the most cases are.

See Smog map of Europe. ,https://www.nzz.ch/wissenschaf…er-coronakrise-ld.1546699

Quote from JedRothwell

Again let me point out that every single expert, at the W.H.O. the CDC and every other agency, says that a vaccine will be developed. They differ only in how long they think it will take. They express no doubts at all that it is possible.

You say it will not happen. Two questions arise: 1. Why not? 2. Are you such an expert in this subject that you know more than all of these experts at major institutions? Tell us about your qualifications, your research, and the papers you have published.

As I said before, one of the most important lessons of cold fusion is that the experts in a field are usually right, and people outside the field are wrong. Also, amateurs and random Wikipedia editors are wrong. Cold fusion researchers have been portrayed as mavericks, but they are just the opposite. As Fleischmann said, "we are painfully conventional people."

With arguments like this, you are destroying even the last hope of developing a vaccine.

All the best to you and everybody here on LF.

Maybe we can use Prep as an antiviral along with Chloroquine?

COVID-19 Drug Therapy — Potential Options
Tim Smith, PharmD, BCPS, and Tony Prosser, PharmD, Clinical Drug Information, Clinical Solutions,
Elsevier | March 2020
According to the World Health Organization (WHO), the Centers for Disease Control and Prevention
(CDC), and the U.S. Food and Drug Administration (FDA), there are currently no medications or vaccines
proven to be effective for the treatment or prevention of the 2019 severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2). (1) (2) (3)
In the absence of an established treatment regimen, the China International Exchange and Promotive
Association for Medical and Health Care (CPAM) issued a novel 2019 coronavirus disease (COVID-19)
guideline in February 2020 with recommendations on methodology, epidemiological characteristics,
disease screening and prevention, diagnosis, treatment and control, nosocomial infection prevention
and control, and disease nursing. For direct antiviral treatment of SARS-CoV-2, CPAM recommends use
of lopinavir; ritonavir [2 capsule (dose undefined) by mouth twice daily] in combination with nebulized
alfa-interferon (5 million units in Sterile Water for Injection inhaled twice daily). CPAM has based this
recommendation on weak evidence from retrospective cohort, historically controlled studies, case
reports, and case series that suggest clinical benefit of lopinavir; ritonavir in the treatment of other
coronavirus infection [i.e., 2002 SARS-CoV and 2012 Middle East respiratory syndrome coronavirus
(MERS-CoV)]. (4) (8) (7)
In addition to CPAM, a group of Korean physicians with experience in treating SARS-CoV-2 infected
patients have developed recommendations for the treatment of COVID-19. According to these
physicians, antiviral medications are not recommended for use in young, healthy patients with mild
symptoms and no underlying comorbid conditions. However, treatment with lopinavir 400 mg; ritonavir
100 mg (2 tablets by mouth twice daily) or chloroquine (500 mg by mouth twice daily) should be
considered for use in older patients or patients with under underlying conditions and serious symptoms.
If chloroquine is unavailable, they recommend considering use of hydroxychloroquine (400 mg by mouth
once daily). Use of ribavirin and interferon were not recommended as first-line treatments because of
the risk for side effects; however, use of these medications may be considered if treatment with
lopinavir; ritonavir, chloroquine, or hydroxychloroquine are ineffective. (12) (13)
Potential future treatment options

How ridiculous when S Korea, Japan, China and Australia are all using it at the same time as running clinical trials.- and how do they know you don't intend using it for an African safari trip?

This must have been a directive from central government to all UK pharmacies not to distribute chloroquine even for malaria just in case somebody tried to treat themselves or maybe a family member who has the early stages of a coronavirus infection. So not only are they totally negligent about funding any research into new therapies whilst most other countries are, they are also trying to stamp out anyone using what is becoming an almost proven successful remedy? Is this the rise of the fourth Reich?

Quote from Dr Richard

This must have been a directive from central government to all UK pharmacies not to distribute chloroquine even for malaria just in case somebody tried to treat themselves or maybe a family member who has the early stages of a coronavirus infection. So not only are they totally negligent about funding any research into new therapies whilst most other countries are, they are also trying to stamp out anyone using what is becoming an almost proven successful remedy? Is this the rise of the fourth Reich?

Quite strange indeed how they seem to want things to take there unfettered course, they do realise that this approach will affect serounding countries? Maybe UK will have higher immunity in the long run.

Quote from Max Nozin

what is the total # new cases in Italy for today?

This is quite a good site to get an overview...unfortunately very dynamic numbers frequently updated based on feedback from local sources...

https://gisanddata.maps.arcgis…740fd40299423467b48e9ecf6