clear blue sky.. crisp spring air in Beijing this 13Mar morning
..looks like Made in China is just starting to get back to making
or dialectical materialism
ABC journalist..Bill Birtles walked around the streets this morning after 14 days quarantine, joked with masked pedestrians.
and had some noodles for breakfast in a restaurant.. he avoided the corona beer though
then looked at Xi Jinping's wisdom..
Coronavirus transspecies effect.
Spare a thought for the Thai monkeys
rioting over 1 banana.. or a toilet roll?
The last number may increase before the end of this day.
Indeed, it went from 1573 to 1716. 143 new cases in a few hours.
Via a footnote in https://www.worldometers.info/coronavirus/
Virus can remain viable "in aerosols up to 3 hours, up to 4 hours on copper, up to 24 hours on cardboard and up to 2-3 days on plastic and stainless steel" a Princeton study awaiting peer review has found
https://www.medrxiv.org/conten…101/2020.03.09.20033217v1
A new (March 12) video from the MedCram team shows that quercetin, like chloroquine, increases intracellular zinc --
Coronavirus Pandemic Update 35: New Outbreaks & Travel Restrictions, Possible COVID-19 Treatments
Some other candidates for zinc ionophores may be found in --
A simple liposome assay for the screening of zinc ionophore activity of polyphenols
up to 2-3 days on plastic and stainless steel"
I laundered my small change this morning.. the 250 beercans from the two alcoholics next door were OK
since they are recluses and get 21 dozen delivered every two weeks
the vouchers from the Tomra machine were OK
but the cash machine at Woolworth's gave me about ten coins in small change..for the $25..
how many Covids were active on them?
maybe I shall simply use the Tomra cashfree option..until Woolworth's launders their cash
bill birtles in a recovering beijing
Display MoreMax Nozin , JedRothwell . I think the UK has a pretty food statistical basis for the suggested 10,000 cases. Something like 20,000 people have been tested, and they are accelerating the program as reported by the BBC -
'With the number of UK coronavirus cases set to rise, NHS England says it is scaling up its capacity for testing people for the infection 10,000 tests a day can be done - 8,000 (sic) more than the 1,500 being carried out currently. Confirmation of any positive test results will be accelerated, helping people take the right action to recover or quickly get treatment.'
And on a related topic, thanks to Mitch Swartz for spotting this heartening reminder of the power of the internet... https://hackaday.com/2020/03/1…n-open-source-ventilator/
This is the KEY issue in the outbreak. I'd like to believe you, but I don't.
(1) UK was testing traced people + those with acute pneumonia. Neither measurement serves to determine the number of people infected showing symptoms so mild they would not be tested.
(2) Everyone will tend to be optimistic as long as possible about this, because a lower number of silent cases means a higher percentage of the population needing treatment, a higher percentage dying.
So I'm staying open on this. Is the "10-20X" more silent infections than counted correct for UK, Italy? Or is it not. It will make a very big difference to everyone which is the case.
This Canadian doc is cool so far https://globalnews.ca/news/6662348/kingston-lab-covid-19/
echoes some NHS plans
Thanks Sam
Is there enough sample data to determine what is timing, say in Italy or South Korea, Japan etc, from initial diagnosis to peak to recession of infections?
1 week, 1 month, 90 days etc?
Imagine it would look like a bell curve but unsure and would like to see some hard data.
his is the KEY issue in the outbreak. I'd like to believe you, but I don't.
I suggest you take that up with the UK's Chief Medical Officer and Chief Scientific Adviser.
Is there enough sample data to determine what is timing, say in Italy or South Korea, Japan etc, from initial diagnosis to peak to recession of infections?
1 week, 1 month, 90 days etc?
Imagine it would look like a bell curve but unsure and would like to see some hard data.
Too early for a bell curve (or hint of one from anywhere but China. However, I would expect to see a skewed curve, sharp rise at the front. slow trail-off at the end. This baby is here to stay it seems, so an infection rate of zero is a find hope.
An hour ago:
New Roche test-set allowed. The PCR station can now do 4000 test/day with 3 hours response-time.
Now its possible to do >100'000 tests a day in countries that own a larger number of the high tech gadgets.
An hour ago:
New Roche test-set allowed. The PCR station can now do 4000 test/day with 3 hours response-time.
Now its possible to do >100'000 tests a day in countries that own a larger number of the high tech gadgets.
that will cause a spike in numbers once deployed
Display MoreThis is an old paper relating to Sars, but evidence is starting to emerge that it is a helpful treatment for Covid 19.
Virol J. 2005 Aug 22;2:69. Chloroquine is a potent inhibitor of SARS coronavirus infection and spread.
Vincent MJ1, Bergeron E, Benjannet S, Erickson BR, Rollin PE, Ksiazek TG, Seidah NG, Nichol ST.
Severe acute respiratory syndrome (SARS) is caused by a newly discovered coronavirus (SARS-CoV). No effective prophylactic or post-exposure therapy is currently available.
RESULTS:We report, however, that chloroquine has strong antiviral effects on SARS-CoV infection of primate cells. These inhibitory effects are observed when the cells are treated with the drug either before or after exposure to the virus, suggesting both prophylactic and therapeutic advantage. In addition to the well-known functions of chloroquine such as elevations of endosomal pH, the drug appears to interfere with terminal glycosylation of the cellular receptor, angiotensin-converting enzyme 2. This may negatively influence the virus-receptor binding and abrogate the infection, with further ramifications by the elevation of vesicular pH, resulting in the inhibition of infection and spread of SARS CoV at clinically admissible concentrations.
CONCLUSION
Chloroquine is effective in preventing the spread of SARS CoV in cell culture. Favorable inhibition of virus spread was observed when the cells were either treated with chloroquine prior to or after SARS CoV infection. In addition, the indirect immunofluorescence assay described herein represents a simple and rapid method for screening SARS-CoV antiviral compounds.
PMID: 16115318 PMCID: PMC1232869 DOI: 10.1186/1743-422X-2-69
[Indexed for MEDLINE] Free PMC Article
Thanks, Alan Smith , it is highly probable this is right, this is after all SARS2, but you know that no authorities will recommend it publicly, so knowing this will help those with enough wisdom to not wait for authorities to come to save the day.
It’s really cheap around here but is not really available without medical indication as it is controlled for not allowing self treatment as this area has erradicated mosquitoes many times and the health authorities want to know if there is any case of diseases that need this.
Thanks, Alan Smith , it is highly probable this is right, this is after all SARS2, but you know that no authorities will recommend it publicly, so knowing this will help those with enough wisdom to not wait for authorities to come to save the day.
It’s really cheap around here but is not really available without medical indication as it is controlled for not allowing self treatment as this area has erradicated mosquitoes many times and the health authorities want to know if there is any case of diseases that need this.
well, you can get to put in your fish tank. OK not human grade but …..
