Covid-19 News

Quote from seven_of_twenty

One can overdose on any of a number of common everyday drugs and die.

Even water can be overdosed. Just google for water drinking contest that killed a woman after drinking 7l of water for getting the first price - the last of her live...

Quote from seven_of_twenty

acetominophen

acetaminophen .. sorry to be picky..

Checking the doses is Totally Important.. Iatrogenic death caused by by nurses and physicians with any drug have and willoccur..

People doing their own dosing need to check with knowledgeable someones (at least 2) before

taking the dose..

Also the source.. needs to be checked of course.. you might get cornflour..

Quote from RobertBryant

the theraputuc dose for malaria prophylaxis by HCQ (hydroxyCQ) is only 5 mg/kg)

much lower than 20 mg/kg.toxic levle for CQ

FYI, the lethal dose of quinine is 850–950 mg/kg and the therapeutic dose is 8.5 mg/kg

it has a much wider separation (factor of 100 not 4).

Quote from oldguy

the lethal dose of quinine is 850–950 mg/kg and the therapeutic dose is 8.5 mg/kg

Cheers...oldguy.. 2 tsp per glass of gin should be OK.. if not a trifle bitter

of course there is the rectal route..

Quote from RobertBryant

Cheers...oldguy.. 2 tsp per glass of gin should be OK.. if not a trifle bitter

of course there is the rectal route..

well it can have side effects like heart attack and long time use loss of eye sight. But they seem to be rare..

And there are problems when used with some other drugs.

Taiwan re engineering for Covid ( = Wuhan coronavirus)

https://focustaiwan.tw/society/202003240015

"In industrial parks across northern Taiwan, a team of some 100 technicians has spent the last six weeks

assembling 92 surgical face mask production lines that will boost the country's daily production capacity

from 4 million to 13 million masks.

“Success depends upon previous preparation, and without such preparation there is sure to be failure.”

— Confucius

Here is one set of contraindications (precautions). Except for allergy, these are conditional, not absolute. As always, consult your physician and do not rely on internet sources including me.

Quote

You should not use Plaquenil if you are allergic to hydroxychloroquine, or if you have a history of vision changes or damage to your retina caused by hydroxychloroquine or similar anti-malaria medications. Before using Plaquenil, tell your doctor if you are allergic to any drugs, or if you have psoriasis, porphyria, liver disease, alcoholism, or glucose-6-phosphate dehydrogenase (G-6-PD) deficiency.

They left out heart disease, particularly congestive heart failure with or without prolonged Q-T syndrome. Once again, daily EKG's and liver and kidney function tests are recommended if taking this for COVID-19. Obviously, you can't always do that. A simple inexpensive ($*( US) EKG app is available from Amazon with maybe some delay. Search for "Kardia." I have one. They work great. You can email the tracings... no need to do it yourself, or fun and profit. I'm not sure why not recommended with pacemakers and ICD's (intracorporeal defibrillators, I think). A cardiologist would know. I doubt it would injure the patient (the battery in the device is 3V and presumably isolated from the input anyway. Maybe it injures the device. Or maybe the trace is hard to interpret. I don't know. I wish they would say.

Quote

Works with most smartphones & tablets. See compatible devices below. Not recommended for use with pacemakers and ICDs. 200 hours operational time

Iceland is interesting:

"The finding is that up to 80% of people testing positive for COVID-19 might not have COVID-19. In other words, most people who get tested for this infection whose tests say they are infected might not be infected. "

"50% of People with COVID-19 Not Showing Symptoms, ~50% Have Very Moderate Cold Symptoms"

https://cleantechnica.com/2020…y-moderate-cold-symptoms/

https://theweek.com/speedreads…isted-calling-wuhan-virus

Large scale testing of general population in Iceland underway

https://www.government.is/news…tion-in-Iceland-underway/

They had planned for larger studies but ran out of swabs.

Large scale testing of general population in Iceland underway

Quote from oldguy

Iceland is interesting:

"The finding is that up to 80% of people testing positive for COVID-19 might not have COVID-19. In other words, most people who get tested for this infection whose tests say they are infected might not be infected. "

"50% of People with COVID-19 Not Showing Symptoms, ~50% Have Very Moderate Cold Symptoms"

https://cleantechnica.com/2020…y-moderate-cold-symptoms/

https://theweek.com/speedreads…isted-calling-wuhan-virus

Large scale testing of general population in Iceland underway

https://www.government.is/news…tion-in-Iceland-underway/

They had planned for larger studies but ran out of swabs.

Large scale testing of general population in Iceland underway

Display More

I could not find the source for this?

Zachary Shahan

https://cleantechnica.com/2020…y-moderate-cold-symptoms/

CV tests have false positives

note Elon Musk comment .. up to 80%

"Abstract in English , Chinese

Objective: As the prevention and control of COVID-19continues to advance, the active nucleic acid test screening in the close contacts of the patients has been carrying out in many parts of China. However, the false-positive rate of positive results in the screening has not been reported up to now. But to clearify the false-positive rate during screening is important in COVID-19 control and prevention. Methods: Point values and reasonable ranges of the indicators which impact the false-positive rate of positive results were estimated based on the information available to us at present. The false-positive rate of positive results in the active screening was deduced, and univariate and multivariate-probabilistic sensitivity analyses were performed to understand the robustness of the findings. Results: When the infection rate of the close contacts and the sensitivity and specificity of reported results were taken as the point estimates, the positive predictive value of the active screening was only 19.67%, in contrast, the false-positive rate of positive results was 80.33%. The multivariate-probabilistic sensitivity analysis results supported the base-case findings, with a 75% probability for the false-positive rate of positive results over 47%. Conclusions: In the close contacts of COVID-19 patients, nearly half or even more of the 'asymptomatic infected individuals' reported in the active nucleic acid test screening might be false positives.

.

Quote from THHuxleynew

I could not find the source for this?

it is in

https://cleantechnica.com/2020…y-moderate-cold-symptoms/

that I listed

first full paragraph:

Also, there is an update on the bottom of the article about the only study I’ve seen on the prevalence of false positive tests in COVID-19 testing. This is not about Iceland specifically. The study was actually conducted in China. However, the conclusion throws a wrench in this Iceland study and any others if it’s broadly relevant. The finding is that up to 80% of people testing positive for COVID-19 might not have COVID-19. In other words, most people who get tested for this infection whose tests say they are infected might not be infected. I’m eagerly awaiting more information on this matter, since it’s a critical factor in the results of any testing or analysis of COVID-19.

https://www.government.is/dipl…tion-in-Iceland-underway/

The director of deCODE has the genetic equipment to take on the Iceland bureaucrats..(w/o Viagra)

perhaps we will see the actual report released this week..

So, if a study say 50% of a random sample test positive and there is an 80% chance of false positive then

there are only 20% of the 50% positive that are "real" and only about 10% out there untested that may have it.

Now, I am not sure if the 80% and 50% are right but it gives you something to think about.

if accurate, then the real number of cases is just1.1 times the current case numbers and not the doom and gloom guesstimate numbers I have been seeing floating around.

Not really sure how they determined if they were false positives for sure.

I think we have an issue with what source means.

I'd dearly like somone to link the source of this 80% negative data?

To avoid misunderstanding. I read the first full para that oldguy quotes. That says "there is an update at the bottom of the page which ...". I expected this update to be the source of this stuff. I could not find it. But that is probably just I did not see it, which is why I asked if anyone could link it.

RB links a twitter post, with a link that looks like it is the source. That is great, very helpful, but...

The link is not traversible because it is a jpg and the url is not seen in text!

Please, people, just give us the source link if you have it? Then it is possible to see whether the second-hand analysis of its content is sound?

THH

PS. Internet false info is prevalent. Especially about things where no-one knows yet.

This site is better than many in distinguishing between fact and internet factoid. At least some here are, which is enough. Let's try to keep it that way?

HydroxyCQ in short supply..worldwide..

no wonder India put an embargo on it...

Source: https://www.statnews.com/staff/ed-silverman/

"“Some healthcare professionals are acting like Walmart shoppers cleaning out the toilet paper

and hand sanitizer aisles by creating personal stockpiles of potentially critical medications just in case they need them"

https://www.statnews.com/pharm…onavirus-covid19-malaria/

Quote from THHuxleynew

Then it is possible to see whether the second-hand analysis of its content is sound?

Iceland government announcement..

The real "details" source is the latest deCODE report which is awaiting approval by the bureaucrats..AFAIK

might take some time.... VIking magic genetic secrets?

https://www.information.dk/ind…7hUblskyfSTixksXWfUWBprVc

https://www.ruv.is/frett/tvenn…cqqIlZ83F45JOnuieG7AVdcoE

Quote from RobertBryant

Results: When the infection rate of the close contacts and the sensitivity and specificity of reported results were taken as the point estimates, the positive predictive value of the active screening was only 19.67%, in contrast, the false-positive rate of positive results was 80.33%.

Switzerland does always two tests Only after two positive ones the case starts.

Taiwan timeline

People might ask what is a CECC?

https://www.abc.net.au/news/20…d-data-explained/12089028

31 December 2019, Taiwan Centers for Disease Control (CDC) implemented inspection measures for inbound flights from Wuhan, China

in response to reports of an unidentified outbreak.^[27] The passengers of all such flights were inspected by health officials before disembarking.^[27]

At this time, there was alleged to be 27 cases of the new pneumonia in Wuhan.^[28]

By 5 January 2020, the Taiwan CDC began monitoring all individuals who had travelled to Wuhan within 14 days and exhibited a fever or symptoms of upper respiratory tract infections. These people were screened for 26 known pathogens, including SARS and Middle East respiratory syndrome, and those testing positive were quarantined.^[5]

On 20 January, the government deemed the risk posed by the outbreak sufficient to activate the Central Epidemic Command Center (CECC,

中央流行疫情指揮中心)

..............

...............

March 25 (CECC) on Wednesday announced that it will expand the scope of its COVID-19 coronavirus screening tests to medical and healthcare workers with suspected infection symptoms in order to prevent possible cluster infections in the nation's healthcare system.