The Totally Civil Covid Thread. (Closing 31/05)

  • The only thing I regretted was having let them get me hospitalized in the first place. Had I known how it was going to be, I wouldn’t have ever got into it.

    I certainly Hope to see LENR helping humans to blossom, and I'm here to help it happen.

  • Without the intention to disagree, I am well aware of the official version. Let's hope reality never proves mr. Zaks wrong, We won't know for sure in several years, and it will be already too late for most.

    There is no mechanism by which a small fragment of RNA could enter the nucleus. That is physically impossible. That is the central dogma of modern biology, and it is as certain as evolution or thermodynamics. Foreign RNA enters the body millions of times, in the form of viral infections such as the cold, influenza, or COVID. It never changes the nucleus or DNA. There is no reverse transcriptase in the human body, none in a full COVID virus, and none in this fragment.


    You might as well worry that cells in the body might violate the laws of thermodynamics.

  • Rapid initiation of nasal saline irrigation to reduce severity in high-risk COVID+ outpatients

    https://journals.sagepub.com/doi/10.1177/01455613221123737


    Abstract

    Objective

    To determine whether initiating saline nasal irrigation after COVID-19 diagnosis reduces hospitalization and death in high-risk outpatients compared with observational controls, and if irrigant composition impacts severity.

    Methods

    Participants 55 and older were enrolled within 24 hours of a + PCR COVID-19 test between September 24 and December 21, 2020. Among 826 screened, 79 participants were enrolled and randomly assigned to add 2.5 mL povidone-iodine 10% or 2.5 mL sodium bicarbonate to 240 mL of isotonic nasal irrigation twice daily for 14 days. The primary outcome was hospitalization or death from COVID-19 within 28 days of enrollment by daily self-report confirmed with phone calls and hospital records, compared to the CDC Surveillance Dataset covering the same time. Secondary outcomes compared symptom resolution by irrigant additive.

    Results

    Seventy-nine high-risk participants were enrolled (mean [SD] age, 64 [8] years; 36 [46%] women; 71% Non-Hispanic White), with mean BMI 30.3. Analyzed by intention-to-treat, by day 28, COVID-19 symptoms resulted in one ED visit and no hospitalizations in 42 irrigating with alkalinization, one hospitalization of 37 in the povidone-iodine group, (1.27%) and no deaths. Of nearly three million CDC cases, 9.47% were known to be hospitalized, with an additional 1.5% mortality in those without hospitalization data. Age, sex, and percentage with pre-existing conditions did not significantly differ by exact binomial test from the CDC dataset, while reported race and hospitalization rate did. The total risk of hospitalization or death (11%) was 8.57 times that of enrolled nasal irrigation participants (SE = 2.74; P = .006). Sixty-two participants completed daily surveys (78%), averaging 1.8 irrigations/day. Eleven reported irrigation-related complaints and four discontinued use. Symptom resolution was more likely for those reporting twice daily irrigation (X2 = 8.728, P = .0031) regardless of additive.

    Conclusion

    SARS-CoV-2+ participants initiating nasal irrigation were over 8 times less likely to be hospitalized than the national rate.

  • I won't spend much time here - but for those still following the antivaxxers posting trialsite antivaxxer and obviously antiscience content a comment on this.


    COVID-19 vaccination and mortality in young people during the coronavirus pandemic - Office for National Statistics


    The UK is carefully monitoring death rates amongst different age groups - and open to the possibility that vaccination (amongst many other covid-related causes) might contribute to this.


    Thus far we do have an uptick in young people mortality - but those who bother to look at the data see that it contradicts the antivaxxer anecdote-rich propaganda:


    • There is currently no evidence of a change in the number of cardiac-related deaths or death occurring from any cause after a coronavirus (COVID-19) vaccination in young people aged 12 to 29 years in England.
    • More deaths were registered in young people aged 15 to 29 years in England in 2021 than the average number registered in 2015 to 2019; however, there was no excess in 2021 for deaths from circulatory diseases.
    • We do not yet have a complete picture of how the coronavirus pandemic has affected deaths in young people, because it takes a long time to investigate deaths from external causes; we will continue to monitor the safety of vaccines and the changes in excess deaths.
    • Early indications show deaths in 2020 increased for some causes, particularly suicides in young females and accidental poisonings (mostly drug poisonings) in young males.

    So, basically - as we all know - lockdowns (and now possibly pressure from cost-of-living crisis) affect suicides

    Lack of timely response from health services very overstretched from covid and its backlog - particularly in the area of mental health - affect suicide rates

    Everyone is expecting an uptick in cancer deaths due to longer waiting lists for everything - but it is too early for this to be seen in the figures.


    These things about whole-population health and what affects it are important, and interesting. It is a real shame that sites like trialsite promote anecdote claiming to be scientific study, and opinion that cannot be substantiated, instead of reflective analysis of the statistical picture as it emerges. There is a lot we still don't know. What we DO know contradicts the narrative in the trialsite link.


    For those who want to follow numbers for themselves, and are not professional data scientists (or who are, still do not have 5 hours to spare from a day job to collate data) here is the best resource I know:


    Home | Covid-19 Data Science
    This page aggregates and tries to provide a balanced discussion of research results, data sets, applications and models, and commentaries regarding Covid-19,…
    www.covid-datascience.com

  • Just to note that correlation does imply causation, and we know that many illnesses result in low vitamin D levels. I think there may have been some RCTs testing vit D supplementation in COVID patients that would provide definite info? Or maybe other drugs (ivermectin etc) are reckoned a better bet. We should have international coordination, instead of 4 different trials all looking at ivermectin.

    It is definitely a better bet to try to change the immunomodulation that covid does, than to find an antiviral. I agree Vit D has possibilities here - as do a lot of othrer things!


    Correlation creates confusion! Vitamin D correlates with sunlight exposure. Therefore it correlates with everything sunlight exposure does.

    However there are many things sunlight exposure does that don't involve Vitamin D.

    It turns out the Red and Near Infrared light have a profound effect on COVID and the work has been done to isolate this effect from the Vitamin D effect!

    One place this has been popularized is in Youtube MedCram series, which has had several videos on the topic.

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  • By the way, you will die waiting for an RCT of a non-profitable treatment.

    And RCT's are an inappropriate way to deal with a war or pandemic.

    No one did a RCT of antibiotics in WWII before the Dept of Ag started making it in giant vats.

    When they say "there is insufficient evidence for <<any cheap drug>>" it's dishonest to not complete the sentence with "...and there never will be because FDA has zero budget for trials and private companies aren't allowed to throw money away."

  • ...and by all means, make sure everyone has enough Vitamin D.

    Of all the stupid things doctors say, the fear they have of "vitamin D overdose" is remarkable. They all get taught some 50 year old myth in medical school and never update-- because there is no marketing team paying to update textbook knowledge of any inexpensive treatment.


    I'm not saying Vitamin D is bad, when I'm saying Sunlight (and light exposure) is good.

    Fear of Melanoma from the UV in sunlight is a true concern. And it can be ennumerated and compared to other things.

    It turns out that insufficient sunlight exposure causes 30 times more health damage, than melanoma does.


    For instance, if you have high blood pressure, sunlight can help with that, and that's likely to be way more important than your risk of melanoma. Particularly if you are older and probably won't be waiting 30 years to see if you started a new melanoma today.


    But you don't have to trade melanoma for light exposure. Significant UV is near midday only. So you could avoid the midday sun, like everybody but mad-dogs and Englishmen.


    And light bulbs such as therapeutic Red and NIR or even Blue come with zero elevated cancer risk.

    Saunas provide IR and health benefits without elevated cancer risk.

  • By the way, you will die waiting for an RCT of a non-profitable treatment.

    And RCT's are an inappropriate way to deal with a war or pandemic.

    No one did a RCT of antibiotics in WWII before the Dept of Ag started making it in giant vats.

    When they say "there is insufficient evidence for <<any cheap drug>>" it's dishonest to not complete the sentence with "...and there never will be because FDA has zero budget for trials and private companies aren't allowed to throw money away."

    I'd agree with a lot of this.


    It did however not apply to covid treatment options.


    There were many big govt-funded studies looking at repurposed (essentially zero cost) drugs - for which dexamethazone was the first example - that help with covid. These studies were revolutionary in being adaptive and multi-arm, while having the statistical integrity of one-drug RCTs.


    ivermectin - due to massive PR - and hydroxychloroquine (the lab info case here was stronger) both got many funded studies, ivermectin many large multi-arm randomised trials.


    I think the response finding drugs has been really good - with the exception that social-media generated demands for ivermectin skewed things as well as making it difficult for serious studies to look at ivermectin because of the death threats that anyone releasing negative ivermectin information received. Who would want to add a not good looking drug to their trial if a likely negative results (most drugs tested are negative) might require investigators getting social media death threats and branded as a killer of millions of people?


    I'm not a fan of social media as a tool to influence the world. Rather like taking mob psychology and amplifying it so that it affects people even when not part of a mob baying for blood.


    THH

  • well who knows? Getting clear evidence for any of these hypotheses is remarkably difficult - and the fact that unclear evidence can often be presented as strong evidence muddies the water.

  • Clinical Manifestation, Management, and Outcomes in Patients with COVID-19 Vaccine-Induced Acute Encephalitis: Two Case Reports and a Literature Review

    Clinical Manifestation, Management, and Outcomes in Patients with COVID-19 Vaccine-Induced Acute Encephalitis: Two Case Reports and a Literature Review - PubMed
    The use of COVID-19 vaccines to prevent and control SARS-CoV-2 infections and complications is the most practicable policy worldwide. However, inaccurate…
    pubmed.ncbi.nlm.nih.gov


    Abstract

    Introduction: Vaccination is one of the best strategies to control coronavirus disease 2019 (COVID-19), and multiple vaccines have been introduced. A variety of neurological adverse effects have been noted after the implementation of large-scale vaccination programs.


    Methods: We reported two rare cases of possible mRNA-1273 vaccine-induced acute encephalitis, including clinical manifestations, laboratory characteristics, and management.


    Results: The clinical manifestations might be related to hyperproduction of systemic and cerebrospinal fluid (CSF) cytokines. mRNA vaccines are comprised of nucleoside-modified severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) mRNA, which is translated into SARS-CoV-2 spike protein by the host's ribosomes, activating the adaptive immune response. Exposed mRNA or vaccine components may also be detected as antigens, further resulting in aberrant proinflammatory cytokine cascades and activation of immune signaling pathways. Both patients exhibited significant clinical improvement after a course of steroid therapy.


    Conclusions: The use of COVID-19 vaccines to prevent and control SARS-CoV-2 infections and complications is the most practicable policy worldwide. However, inaccurate diagnosis or other diagnostic delays in cases of vaccine-induced acute encephalitis may have devastating and potentially life-threatening consequences for patients. Early diagnosis and timely treatment can result in a favorable prognosis.

  • Neurological and neuropsychological adverse effects of SARS-CoV-2 vaccines – where do we stand?

    Neurological and neuropsychological adverse effects of SARS-CoV-2 vaccines – where do we stand?
    The devastating characteristic of COVID-19 pandemic calls for immediate and effective solutions to tackle it. Vaccines seem to be the only promising and…
    www.degruyter.com


    Abstract

    The devastating characteristic of COVID-19 pandemic calls for immediate and effective solutions to tackle it. Vaccines seem to be the only promising and effective way to fight against the novel coronavirus – even against new mutated variants. Because of the rapid development and distribution of numerous COVID-19 vaccines in different platforms, meticulous evaluation of vaccines’ safety is more critical than ever – especially given the fact that most of the candidates have not completed the clinical phase. Therefore, to optimize the vaccines’ safety and efficacy, it is highly important to carefully report and scientifically discuss the serious adverse effects following vaccination. In this respect, we discuss different neurological and neuropsychological adverse effects of COVID-19 vaccines including demyelinating diseases, Bell’s palsy (BP), cerebrovascular complications, seizures, functional neurological disorders (FNDs), and some other rare adverse events, and hypothetical mechanisms which can lead to the reported side effects. Given the fact that the incidence of such events are rare and most of them are treatable, the current review aims to shed light on how much the relationship between COVID-19 vaccines and these complications can be reliable and provide an insight for future studies with much more meticulous methodologies to discuss the possible correlational or causal relationship between these complications and COVID-19 vaccines and elucidate whether or not the neurological side effects of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines can count as a considerable threat to public health

  • Neurological and neuropsychological adverse effects of SARS-CoV-2 vaccines – where do we stand?

    The adverse effects are transient, predictable, and limited to a few small, well defined groups. In all but a handful of cases they have caused no serious harm. The likelihood of serious harm is roughly 1 per billion, which is the best safety record in the history of medicine. You are probably more likely to be killed by a falling meteorite than by the COVID vaccine. There are more adverse effects from eating grapefruit than getting a COVID mRNA vaccine.


    Does that answer your question? Fretting about adverse affects is irrational.


    Therefore, to optimize the vaccines’ safety and efficacy, it is highly important to carefully report and scientifically discuss the serious adverse effects following vaccination.

    Yes. They always do report them. In the U.S., they have to, by law. So why even say this?

  • The adverse effects are transient, predictable, and limited to a few small, well defined groups. In all but a handful of cases they have caused no serious harm. The likelihood of serious harm is roughly 1 per billion, which is the best safety record in the history of medicine. You are probably more likely to be killed by a falling meteorite than by the COVID vaccine. There are more adverse effects from eating grapefruit than getting a COVID mRNA vaccine.


    Does that answer your question? Fretting about adverse affects is irrational.


    Yes. They always do report them. In the U.S., they have to, by law. So why even say this?

    Must be a lot of meteorites falling

  • Must be a lot of meteorites falling

    Don't kid yourself. Learn the facts. No one has been killed or seriously hurt by the mRNA vaccines. The adenovirus ones killed a few people. Reports that there have been casualties are written by people who do not understand statistics. Especially the stats as VAERS, which are difficult to interpret. All of these reports are mistaken. For details, see:


    Home | Covid-19 Data Science
    This page aggregates and tries to provide a balanced discussion of research results, data sets, applications and models, and commentaries regarding Covid-19,…
    www.covid-datascience.com

  • Timeline: The proximal origin of SARS-CoV-2

    Timeline: The proximal origin of SARS-CoV-2 - U.S. Right to Know
    Introduction “The proximal origin of SARS-CoV-2” is one of the most influential scientific articles in history. In February 2020 — about a month before a…
    usrtk.org


    Introduction

    “The proximal origin of SARS-CoV-2” is one of the most influential scientific articles in history.


    In February 2020 — about a month before a pandemic had been declared — five top virologists huddled to examine aspects of a rapidly emerging coronavirus that seemed primed to infect human cells. (The furin cleavage site kept one virologist up all night.) A few days later, they concluded the virus had not been engineered. In March, their conclusions were published in Nature Medicine.


    “We do not believe that any type of laboratory-based scenario is plausible,” the article read.


    The article assured much of the media, Washington and the broader infectious disease community that there was no need to scrutinize the labs at the pandemic’s epicenter in Wuhan, China. The Wuhan Institute of Virology is well known for research on SARS-like coronaviruses, including gain-of-function research. Though a “correspondence” and not a formal paper, the article has been cited in the press 2,127 times.


    It took 15 months and a Freedom of Information Act lawsuit to reveal that each of the five authors had expressed private concerns about engineering or the Wuhan Institute of Virology’s store of novel coronaviruses.

  • International Journal of Vaccine Theory, Practice, and Research2(2), August 12, 2022 | 321Self-Selected COVID-19 “Unvaccinated” Cohort Reports Favorable Health Outcomes and Unjustified Discrimination in Global SurveyRobert

    FM1 is good at finding quack journals...


    Is “The International Journal of Vaccine Theory, Practice, and Research” a serious, science-based publication or a mouthpiece for anti-va...
    Answer (1 of 5): Well, let’s see. The first issue features an article about what the “elite plutocrats” (that’s an exact quote) don’t want you to know about…
    www.quora.com


    Obviously this is a quack journal. In addition to the excellent points others have made, look at the editorial board, the supposed experts who direct this publication:

    • Editor-in-chief: John W. Oller, Jr., PhD in General Linguistics from the University of Rochester in New York, now a professor at ipaknowledge.org

      and consultant to Veritas International University… A professor of linguistics, now working at a website and as a “consultant:” how is he a vaccine expert?

    • Senior editor: Christopher A. Shaw, PhD, Professor, Department of Ophthalmology, University of British Columbia… A real college at least, but again, wrong area of study.

    But here’s the real kickers in the associate editors list:

    • Mary S. Holland, MA, JD, General Counsel for Children's Health Defense 2019-present; formerly Director Graduate Lawyering Program, New York University School of Law 2004-2019; expertise in children's health and litigation concerning vaccines; renowned author of works in that area. A lot of “former” here, an anti-vaccine litigation professional, and “renowned” author of unlisted “works;” no real journal uses a fluff word like “renowned” in describing its editors.
    • Robert J. Krakow, JD, Law Office of Robert J. Krakow, Representing the Vaccine Injured in All 50 States. All credibility is now gone. This man has a vested interest in seeking or manufacturing evidence against vaccines.

    Always check out a journal’s background and board as well as its content. Lawyers don’t belong on the editorial board of a medical journal.



    and


    If it looks like a duck and quacks like a duck …

    It would be a very confusing title for a “mouthpiece” however, because it would imply that there is at least some theory, practice and research.

    But as I said, sometime you can tell from the smell alone.

    International Journal of Vaccine Theory, Practice, and Research

    is a peer-reviewed scholarly open access journal concerning the development, distribution, and monitoring of vaccines and their components.

    Components? That is a very strange word to use. Why not just “vaccines”?

    This issue begins to explore the language, policies, practices, and science examining the range of known interactions between some of the toxicants in vaccines

    Toxicants? Another very strange word to use. Of course a particular “component” of a vaccine may be “toxic” in some way, but then we would just expect the word “component”.

    So in summary, I think it is quite obvious what it really is.

    • It uses the word “components” when that is implied by “vaccine”.
    • It uses the word “toxicants” when that is not implied by “components”.
    • It uses the word “toxicants” rather than just “toxic components” - and the implication is that many of the components are inherently “toxic” when the science of vaccines is based on immunology, not on toxicity in application.
    • It “explores language” which is a purely propaganda objective - in other words, it already has an obvious objective, which is nothing to do with the theory, practice and research of vaccines in themselves.

    And of course the more we read, the more we realise we have seen this sort of thing before, all too often.

    It is an attempt at self-delusion.

    The duck thinks that by looking like a swan, and honking like a swan, it is a swan. It tries to pretend it is a valid source of science information.

    But it looks like a duck, quacks like a duck, stinks like a propaganda mouthpiece, and therefore is one.

    And what is so sad about this is that it is still so badly done, even when they have put so much effort into it. They are so delusional as to believe what they upload, just by giving us something that looks like the real thing.

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