The Totally Civil Covid Thread. (Closing 31/05)

  • Varicella-Zoster Reactivation after COVID-19 Illness versus SARS-CoV-2 Vaccination

    Larger Ongoing Threat is COVID-19 Vaccination

    Varicella-Zoster Reactivation after COVID-19 Illness versus SARS-CoV-2 Vaccination
    Larger Ongoing Threat is COVID-19 Vaccination
    petermcculloughmd.substack.com


    By Peter A. McCullough, MD, MPH


    Many papers in the medical literature seem to pit a consequence such as myocarditis or stroke as either occurring as a consequence of COVID-19 illness compared with COVID-19 vaccination. Because the denominator is so large for acutely ill hospitalized patients with COVID-19 especially during the first two years of the pandemic allowing ICD code capture of comorbidities, authors erroneously conclude the illness is “more dangerous” or a “bigger risk factor.” These arguments are daft in my opinion since COVID-19 respiratory illness is treatable and a recent paper from Klaassen et al has estimated 94% are already recovered from COVID-19—so it is water under the bridge. Not true for COVID-19 vaccines which are still mandated by some ill-advised schools, employers, and agencies. One way of looking for what is a more pressing and continued problem is to survey the medical literature.

  • Many papers in the medical literature seem to pit a consequence such as myocarditis or stroke as either occurring as a consequence of COVID-19 illness compared with COVID-19 vaccination.

    Mostly fake info. 1-2 cases among patients that died !!!! in ICU from lung inflammation....


    Like Covid deaths from car accident... or brain stroke....


    Remember the ridiculous new York Times that makes ("in fact made" - they stopped publishing hospital data...) people believe Covid happens only in patients admitted to hospitals? They also publish a mortality that is 20x to high in relation to the cases. Omicron mortality overall is far below 0.1%. If you have a flue, diabetes and also they find Omicron, you die from Omicron not from flu what is more likely.


    But NYT is in TNI the big pharma sponsored propaganda publishing union.

  • Advanced vitamin D topics - some people need much more D3 than normal, to suppress rheumatoid arthritis, multiple sclerosis, psoriasis, cluster headaches, migraines etc.; Newly discovered vitamin D compounds; The impact of lack of helminths on inflammatory responses, including severe COVID-19

    Advanced vitamin D topics - some people need much more D3 than normal, to suppress rheumatoid arthritis, multiple schelrosis, psoriasis, cluster headaches, migraine etc.; newly discovered vitamin D compounds


    This page assumes a strong interest in biology and treatment arrangements which go not only beyond many MD's limited knowledge of vitamin D, but also beyond a properly informed knowledge of the needs for most people for D3 supplementation to enable the immune system to work well, as described in the above-mentioned page.


    If you have this strong interest, a reasonable knowledge of biology and the ability to make your own decisions, even tentatively so, about your own and your family's health, then you might like to join the Nutrition for Immune System Health (NISH) email discussion list: https://NISH.groups.io . This is a high-signal-to-noise ratio discussion group with MDs and nurses (only one so far), leading vitamin D researchers (many of whom are MDs), nutritionists, as well as autodidacts such as myself with no formal qualifications.


    On 2021-10-02 I added mention of new research on helminths (intestinal worms) including how active helminth infections in Ethiopia are associated with a 77% reduction of incidence of severe COVID-19. This is really interesting and makes good sense once the evolutionary history of helminth infections and the immune system is understood

  • Vitamin D and Risk for Type 2 Diabetes in People With Prediabetes

    A Systematic Review and Meta-analysis of Individual Participant Data From 3 Randomized Clinical Trials

    https://www.acpjournals.org/doi/full/10.7326/M22-3018


    The association between vitamin D serum levels, supplementation, and suicide attempts and intentional self-harm

    The association between vitamin D serum levels, supplementation, and suicide attempts and intentional self-harm
    Objectives The purpose of this study is to determine the associations between Vitamin D supplementation, 25(OH) blood serum levels, suicide attempts, and…
    journals.plos.org


    Vitamin D deficiency linked to higher risk of miscarriage

    Women with low vitamin D levels are more likely to suffer a miscarriage

    Vitamin D deficiency linked to higher risk of miscarriage - University of Birmingham
    Women with low vitamin D levels are more likely to suffer a miscarriage.
    www.birmingham.ac.uk


    Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial

    Vitamin D and marine omega 3 fatty acid supplementation and incident autoimmune disease: VITAL randomized controlled trial
    Objective To investigate whether vitamin D and marine derived long chain omega 3 fatty acids reduce autoimmune disease risk. Design Vitamin D and omega 3…
    www.bmj.com



    What happened to the liers deniers and huxsters? Cowards!!!!

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  • UK excess deaths close to normal for one week:: https://www.ons.gov.uk/peoplep…l/weekending27january2023


    May be the hope is becoming real. Less Covid, less ADE, less damage.


    Switzerland is stable on low cases level. International centers (universities) - most likely imported cases - produce more cases.

    Covid-⁠19 Schweiz | Coronavirus | Dashboard
    Covid-⁠19 Pandemie Schweiz und Liechtenstein: Fallzahlen, Virusvarianten, Hospitalisationen, Spitalkapazitäten, Zahlen zu Tests, Impfungen und Viruslast im…
    www.covid19.admin.ch


    We have no masks since > 1 year...

  • Reports of Cancer Following COVID-19 Vaccines

    Reports of Cancer Following COVID-19 Vaccines
    With continued concerns surrounding COVID-19 vaccines’ adverse effects, some suggest that there may be an increased risk of developing cancer following…
    www.trialsitenews.com


    With continued concerns surrounding COVID-19 vaccines’ adverse effects, some suggest that there may be an increased risk of developing cancer following COVID-19 vaccination. TrialSite reviews data from the CDC’s Vaccine Adverse Event Reporting System (VAERS) and relevant scientific research to assess this claim. TrialSite previously reported on Cytokine Release Syndrome (CRS), which can present as hypotension, hypoxia, and even organ failure, occurring after vaccination in a cancer patient undergoing cancer therapy. While this indicates an interaction between vaccination and cancer therapies, there are also questions surrounding vaccination and cancer development.


    COVID-19 vaccines may lead to various adverse events (AEs) in recipients, but it has not been confirmed whether cancers develop after taking the COVID-19 vaccine.


    When the VAERS database is searched for all reports of adverse events related to all COVID-19 vaccines with symptoms that include the word “cancer” from the years 2020 to 2022, a total of 1,518 events are returned; however, as some are registered in more than one category or more than one symptom, the total number of reports is 1,732. Cancers include cervix carcinoma, hepatic cancer, lung cancer, ovarian cancer, and pancreatic cancer among others, also including different possible stages and metastasis.


    The number of adverse events by vaccine brand and year can be seen in the table below:


    Vaccine


    AEs reported in 2021


    AEs reported in 2022


    Total


    Janssen JNJ-78436735 (Ad26.COV2.S)


    53


    63


    116


    Moderna mRNA-1273


    312


    377


    689


    Moderna Bivalent


    0


    8


    8


    Novavax NVX-CoV2373


    0


    1


    1


    Pfizer/BioNTech BNT162b2


    395


    501


    12


    Pfizer/BioNTech Bivalent


    0


    12


    896


    Unknown


    0


    7


    7


    Total


    760


    969


    1729



    However, the CDC warns VAERS users that “VAERS reports alone cannot be used to determine if a vaccine caused or contributed to an adverse event or illness.” This is because anyone can submit adverse effects to VAERS, introducing information that may be incomplete, incorrect, or biased. Nevertheless, the question of any link between COVID-19 vaccines and cancer still stands.


    mRNA Vaccines and Cancer

    TrialSite has previously mentioned an article by Jiaquing Wu, Ph.D., in which he argues that mRNA vaccines could increase the rate of cancer development by impairing the CNS through severe adverse effects, which in turn would negatively impact the immune system. Wu cites immune system compromise as one factor in cancer development. He also indicates that mRNA vaccine impacts on the CNS might unintentionally lead some cancers to spontaneously clear.


    Immune dysregulation

    There are several articles that suggest that COVID-19 vaccines disrupt the immune system, which may eventually lead to the formation or development of cancer.


    One article discusses how mRNA COVID-19 vaccines strongly activate T follicular helper cells, as evidenced in an unexpected and rapid progression of lymphoma in a 66-year-old patient following the administration of a Pfizer/BioNTech mRNA vaccine booster. T follicular helper cells are found in the spleen, tonsils, and lymph nodes, and are important for antibody production against foreign pathogens. However, overstimulation of these cells by COVID-19 vaccines could be linked to cancer progression in the lymphatic system.


    One recorded adverse event for both Pfizer and Moderna vaccines is lymphadenopathy, or the swelling of the lymph nodes, which is a typical secondary effect of immune system activity against infections or autoimmune diseases. However, lymph node swelling is often unrelated to cancer and caused by another condition or general immune activation.


    A second article suggests that both Pfizer/BioNTech and Moderna mRNA vaccines promote sustained synthesis of the SARS-CoV-2 spike protein, which is neurotoxic and impairs DNA repair mechanisms. The writers find that type one (I) interferon (IFN) responses are suppressed, resulting in impaired immunity because type I IFNs are key protein signals for regulating the immune system and producing cytotoxic T cells that can attack tumors.


    Apart from suppressing type I IFN responses, COVID-19 vaccines may also increase autoantibodies that attack the protein, as shown in this case of a 50-year-old woman. She had an uncharacteristically high number of antibodies in her blood that were targeting her own type I IFN after receiving the second shot of the Moderna COVID-19 vaccine, which further increased following her third shot. The authors note that immune responses to type I IFN can boost overall immune response, which is great for vaccine efficacy, but can also accelerate autoimmune disease pathogenesis.


    Autoimmune disorders and cancer

    One case study tells of a 72-year-old man who developed Acquired Hemophilia A (AHA), a severe autoimmune blood disorder, and dermal tumors during a period of Moderna booster vaccination. The authors also note that certain immunosuppressive drugs used to treat AHA can also increase the risk of “new or newly unmasked, rapidly proliferating malignancy,” suggesting a potential link between autoimmune disorder treatment and cancer detection or progression that is independent of COVID-19 vaccination.


    Further support for autoimmune disruption following COVID-19 vaccination can be found in this article, where the authors cite studies they claim have shown that “autoimmune abnormalities appear simultaneously with COVID-19 infection,” and that such abnormalities have been demonstrated as adverse effects. The authors highlight that molecular similarity between COVID-19 antigens and self-antigens could lead to these autoimmune irregularities, which is suspected to have caused the pemphigus vulgaris in the patient who also happened to have undiagnosed cancer.


    Cases in non-human animals

    In April 2022, it was reported that 66 animals at the Calgary Zoo received COVID-19 vaccinations. Of these animals, one 6-year-old gorilla named Kimani was of particular concern following reports of life-threatening pediatric liver cancer about two months later.


    Despite public concern that the vaccine was linked to cancer formation in the gorilla, the zoo claimed in a Facebook post that the two events were not related and that Kimani’s behavioral changes, which prompted diagnostic testing, had begun 4 months prior in February 2022, whereas vaccination did not occur until April. They also reported that no side effects were noted in any of the other vaccinated animals.


    At San Diego Zoo, about 260 animals received a COVID-19 vaccine in 2021, with no apparent information available concerning any adverse effects. It can be noted that, according to the zoo, one orangutan, Satu, passed away for reasons related to cancer. Vaccines were administered in June 2021, and Satu passed away on December 22 of the same year. However, it appears that he hadalso been battling another illness, although that information is also not clear.


    Alternative Explanations

    Healthcare workers should also be aware of the possibility of a false-positive cancer screen or diagnosis occurring even when hypermetabolic lymph nodes appear far from the vaccination site of COVID-19 vaccinations.


    The September 2021 issue of Human Vaccines and Immunotherapeutics contains a case study of a 33-year-old woman who had vaccine-associated hypermetabolic lymphadenopathy (VAHL) after vaccination with the AstraZeneca COVID-19 vaccine. VAHL is reported in the article as being relatively common. Since the patient had a history of successfully-treated classic Hodgkin’s lymphoma (CHL), when unexpected small hypermetabolic cervical and abdominal lymph nodes were imaged in the same location as at the onset of the CHL, medical practitioners suspected radiological relapse. The authors also obtained an image two months later, where they observed decreased lymph nodes among other normal test parameters.


    It is also possible that exposure to an environmental toxin is responsible for the development of AEs during the pandemic. A study by the independent laboratory Valisure found that 44 out of 260 samples of hand sanitizer came back positive for benzene, an industrial chemical that can cause leukemia and other serious long-term health issues. Sanitizer use was prioritized from the start of the pandemic as an essential and accessible tool for fighting the spread of the virus, so it is worth considering the health effects of sanitizers during their increased use in the general community as well.


    mRNA vaccines and cancer treatment

    The spontaneous clearing of cancers post-vaccination is supported by research published in the Journal for Immunotherapy of Cancer in March 2022. The authors report on a patient who experienced a significant reduction in their salivary gland cancer after receiving the Moderna mRNA-1273 vaccine. The patient’s CT scans taken three, six, and nine months after the second vaccine dose showed continual tumor shrinkage, suggesting possible anticancer immunity generated by the vaccine. The authors also explain that this tumor regression may occur following an increased immune response, which is expected to occur after receiving a vaccine.


    There is also growing research in using mRNA vaccines to treat cancer, as reported in this article from the British Medical Journal. According to this article, mRNA holds promise amidst other vaccination methods because of how rapidly mRNA vaccines can be modified to suit each patient’s developing cancer. As of November 2022, one experimental vaccine delivered intravenously is already showing promising results in treating cancers by inducing type I IFN production, which in turn increases the effectiveness of T cells to attack tumors.


    Conclusion

    More studies are needed to verify or disprove that COVID-19 vaccines, particularly mRNA vaccines, may be linked to cancer formation and progression. This is especially true considering that the suite of currently available studies is mainly case reports or studies that have not been reproduced extensively.


    TrialSite previously reported on a mainstream media interview with the CEO, Transformative Health Justice Shabnam Mohamed concerning the recent announcement by the South African Ministry of Health. The ministry states that five to 11-year-olds will start being vaccinated despite reports of adverse events following COVID-19 vaccination, which begs the question: if there is no conclusive evidence against cancer AEs following vaccination, should such young children be receiving vaccines?

  • Therapeutic effect of combination vitamin D3 and siponimod on remyelination and modulate microglia activation in cuprizone mouse model of multiple sclerosis

    Therapeutic effect of combination vitamin D3 and siponimod on remyelination and modulate microglia activation in cuprizone mouse model of multiple sclerosis
    Stimulation of remyelination is critical for the treatment of multiple sclerosis (MS) to alleviate symptoms and protect the myelin sheath from further damage.…
    www.frontiersin.org


    Stimulation of remyelination is critical for the treatment of multiple sclerosis (MS) to alleviate symptoms and protect the myelin sheath from further damage. The current study aimed to investigate the possible therapeutic effects of combining vitamin D3 (Vit D3) and siponimod (Sipo) on enhancing remyelination and modulating microglia phenotypes in the cuprizone (CPZ) demyelination mouse model. The study was divided into two stages; demyelination (first 5 weeks) and remyelination (last 4 weeks). In the first 5 weeks, 85 mice were randomly divided into two groups, control (n = 20, standard rodent chow) and CPZ (n = 65, 0.3% CPZ mixed with chow for 6 weeks, followed by 3 weeks of standard rodent chow). At week 5, the CPZ group was re-divided into four groups (n = 14) for remyelination stages; untreated CPZ (0.2 ml of CMC orally), CPZ+Vit D3 (800 IU/kg Vit D3 orally), CPZ+Sipo (1.5 mg/kg Sipo orally), and CPZ+Vit D3 (800 IU/kg Vit D3) + Sipo (1.5 mg/kg Sipo orally). Various behavioral tasks were performed to evaluate motor performance. Luxol Fast Blue (LFB) staining, the expression level of myelin basic protein (MBP), and M1/M2 microglia phenotype genes were assessed in the corpus callosum (CC). The results showed that the combination of Vit D3 and Sipo improved behavioral deficits, significantly promoted remyelination, and modulated expression levels of microglia phenotype genes in the CC at early and late remyelination stages. These results demonstrate for the first time that a combination of Vit D3 and Sipo can improve the remyelination process in the cuprizone (CPZ) mouse model by attenuating the M1 microglia phenotype. This may help to improve the treatment of MS patients.

  • Reports of Cancer Following COVID-19 Vaccines

    RNA gene therapy is by definition of the inventor an experimental cancer gene therapy. Rebranding it as a vaccine is business level talk and does not hold on the scientific level.

    RNA gene therapy does not produce a vaccine like immune answer. Basically its the same picture as seen from an acquired allergy. Allergy followup reactions are not the normal immune reactions, we see during a re-infection. An allergy usually produces a point like IgG that produces just a single brand of antibody IgA what very fast leads to an over reaction. A normal immune reaction is adaptive and produces a large set of similar antibodies from multiple IgG. The best fitting then are ramped up where as in an allergy picture the wrong ones are ramped up what leas to ADE as the immune system cannot produce optimal antibodies.


    Of course this - in the spike case - supports cancers of all form because the unchanged IgA of the the spike suppress the interferon 1 path - a key pillar of the immune system.

    My hair dresser has large customer base, that did see a bigger loss due to turbo cancer eradicated customers...

    So lets hope the virus will go away (no more ADE) and the damaged people will down regulate their useless spike IgA...

  • Hyperbaric Oxygen for Treatment of Long COVID-19 Syndrome (HOT-LoCO)

    Trial Protocol Gives an Outline for a Clinical Approach

    Hyperbaric Oxygen for Treatment of Long COVID-19 Syndrome (HOT-LoCO)
    Trial Protocol Gives an Outline for a Clinical Approach
    petermcculloughmd.substack.com


    By Peter A. McCullough, MD, MPH


    Many followers have been clamoring for some approach to post-COVID-19 syndromes. I have tried many therapies in clinical practice and have been disappointed with my observations. Approximately 50% of patients hospitalized with severe respiratory COVID-19 suffer from post-COVID-19 syndromes including weakness, depression, muscle fatigue and loss of mass, hair loss, sleep disturbance, anosmia, tinnitus, headaches, and general inanition. The observational studies suggest these symptoms are transient and will resolve over time. However, patients are suffering now and want a pathway to prompt recovery. Several observational studies and one small randomized trial demonstrated salutary effects of hyperbaric oxygen therapy (HBOT) consisting of a series of treatments with the whole body in a HBOT chamber where the partial pressure of oxygen is modified to levels used to treat chronic wounds and other medical problems.

  • Covid ‘shaming’ shifted focus from UK government failures, study says

    Creating conditions in which people suffered shame and stigma was ‘cynical’ tactic to steer attention away from errors, says study

    Covid ‘shaming’ shifted focus from UK government failures, study says | Coronavirus | The Guardian


    Creating an environment in which individuals and marginalised groups were shamed during the Covid pandemic was a “cynical” tactic to steer attention away from the UK government’s errors, an academic study has concluded.


    The research by medical humanities scholars at the University of Exeter said people from ethnic minority groups, those with medical conditions such as obesity and health professionals all suffered shame and stigma.


    They argue that by putting the onus on citizens to use their common sense and encouraging people to report rule-breakers rather than formulating cohesive public health policies the perfect conditions for shame to pervade were created

  • Dr Campbell on the WHO..


    I guess I was lucky with Astrazeneca jab,,,,2 yrs ago.. but I was 65

    the WHO still recommends it for 18 yr olds

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    poor guy here did not fare so well... maybe it went into one of his veins?


    "My brother got this shot twice and developed clots in his legs, lungs, and developed heart problems.

    He had one of his legs amputated but he never recovered. He couldn't even go to the bathroom without being totally exhausted and needed constant oxygen. He died about six months later in December of 21.

    He was the healthiest of our siblings. I had never even heard of people getting clots in their legs

    so bad amputation was necessary. He practically begged me to get the shot

    and it was very difficult not to tell him I don't want to end up like you. I would just say I will wait and see how other people are doing first."

  • "As the U.S. plans to relinquish its role as the predominant purchaser of the Covid-19

    vaccine to the commercial sector, vaccine manufacturers

    Moderna and Pfizer have announced plans

    to hike the price of the vaccine by over 400 percent.


    The decision would increase the price from $26 to $110-130 per dose

    , despite it costing only $2.85 to produce.:


    Sign the petition to the Department of Health and Human Services: Stop COVID-19 vaccine price gouging.
    Sign the petition to the Department of Health and Human Services: Stop COVID-19 vaccine price gouging. . Take action here:…
    actionnetwork.org


    Pfizer "The “how” is represented by four simple, powerful values – courage, excellence, equity and joy – that define our company and our culture."

    Moderna "To deliver on the promise of mRNA science to create a new generation of transformative medicines for patients."

  • Fauci " the best vaccination is infection"

    ' follow the science '

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  • Convenient Scientific Memory Lapse? Dr. Anthony Fauci Teaches Us About Viruses & Why the COVID-19 Vaccines Are Limited

    Convenient Scientific Memory Lapse? Dr. Anthony Fauci Teaches Us About Viruses & Why the COVID-19 Vaccines Are Limited
    Recently, Dr. Anthony Fauci just retired from nearly half a century of service at the National Institute of Allergy and Infectious Diseases (NIAID), part of…
    www.trialsitenews.com


    Recently, Dr. Anthony Fauci just retired from nearly half a century of service at the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), teamed with two infectious disease colleagues from NIH, David Morens and Jeffrey Taubenberger to educate the world why after all the current COVID-19 vaccines were not sufficient to take on respiratory diseases such as the novel coronavirus called SARS-CoV-2. After decades of Fauci and team studying these viruses, and after all that we have collectively gone through, horribly divisive mandates and other pandemic-driven madness, the trio of authors report on why places like the NIH will need more money to develop the next generation of vaccines.


    ‘I am Science’

    Let’s first break down and simplify the general message. Here it goes in this author’s arguably biased words:


    Everything was a success. We saved countless lives and even partially controlled the pandemic. But any problems with the vaccines isn’t the fault of the government or industry—it’s the fault of that bad RNA virus. It mutated and just like influenza, that dynamic, which we have known about for decades but for whatever reasons forgot about during the onset of SARS-CoV-2, rendered our vaccines less effective. But we didn’t know any better. If we would have known, we would have come up with more directed strategies based on the fact that SARS-CoV-2, like all coronaviruses and influenza, are mostly upper respiratory viruses. Remember, keep this point top of mind—We are science and we are here to tell you what reality is while investing in the future to keep you safe and healthy with advanced medicines and vaccines.


    The trio of authors pounces on the Omicron opportunity to get a pass for what has been a truly questionable, if not outright failed, vaccination strategy. Fauci and team outright acknowledge that all coronaviruses, like influenza and the common cold, replicate “in the human respiratory mucosa without infecting systematically” while the vaccines NIH helped promote and develop (NIH has some patent interests with Moderna’s vaccine) didn’t focus on this target-rich area (even though they knew well in advance of this science). Yes, they were fully aware of all of this as they embarked on the great COVID-19 pandemic response countermeasure effort.


    But there is more. Fauci and team point out:


    “Because these viruses generally do not elicit complete and durable protective immunity by themselves, they haven’t to date been effectively controlled or licensed by experimental vaccines.” TrialSite from the start of the pandemic challenged Fauci and the NIH—as well as the World Health Organization (WHO)—notion that they could CONTROL and Eradicate an RNA virus such as the novel coronavirus with a blood-based vaccine, or any vaccine for that matter. Just go back and read the many articles since 2020 on this topic.


    The influenza virus, in many ways, is similar, and that vaccine has been hit or miss for decades. The common flu was never eradicated, yet, based on a whim and hope, with novel technology, entire health systems backed by government emergency decree deployed $5.5 trillion in U.S. taxpayer money alone, over nearly a three-year period to, among other things, vaccinate 70% of the population (per the WHO target) with what is, in reality, an investigational vaccine.


    New Targeted Vaccines—That’s the Answer

    Fauci and colleagues in this later paper investigate such challenges impeding the development of effective mucosal respiratory vaccines. After all, the writers remind the reader that these viruses “replicate extremely rapidly in the surface epithelium” and thus “quickly transmitted to other hosts, with a narrow window of time before adaptive immune responses are fully marshaled.”


    Delving into and elaborating on possible methods, Fauci and colleagues’ true calling comes next—the development of “next-generation vaccines against these viruses” with what the authors position as next-level considerations from antigen configuration, dose, and adjunction to route and timing to boosting and other “options for public health vaccination policies.” Nice that the truth comes out as TrialSite has been informing the world for a couple of years now that these vaccines were in reality version 1.0, to use a software comparison.


    We remind all that this is the same person [Fauci] who essentially represented the brain power behind the COVID-19 pandemic response. It was Fauci that gladly stepped into the limelight, directing all those press conferences, television appearances, and YouTube interviews with celebrities also it was he that has, leading NIAID for many years, doled out enormous sums of money to all sorts of infectious disease research including likely, some form of gain-of-function-related support involving EcoHealth Alliance and Wuhan Institute of Virology.


    Fauci knew well in advance what he and colleagues communicated in this recent primer published in Cell Host & Microbe. The authors acknowledge that “after more than 60 years of experience with influenza vaccines, very little improvement in vaccine prevention of infection has been noted.


    Confessing the weakness of current influenza vaccines, the authors post “As pointed out decades ago, and still true today, the rates of effectiveness of our best-approved influenza vaccines would be inadequate for licensure for most other vaccine-preventable diseases. Even decades-long efforts to develop better, so-called “universal” influenza vaccines—vaccines that would create more broadly protective immunity, preferably lasting over longer time periods—have not yet resulted in next-generation, broadly protective vaccines, although a large number of experimental vaccines are in preclinical or early clinical development.”


    A Legacy to Defend

    Of course, Fauci must defend his less-than-stellar pandemic response by going on the offense, shielding what in actuality were the mass distribution and administration of experimental vaccines, support of a terribly divisive and mismanaged response. Fauci, in this author’s opinion, exploited the pandemic for exactly the reason he mentioned in this piece and in the past—that there has been essentially no innovation and associated breakthroughs in vaccine development for over half a century. Thus, the huge emphasis on mRNA and the possibilities which TrialSite concurs represents significant potential, given more time and scientific breakthroughs.


    But they rushed the countermeasures response, part of the declared emergency, which included the shameless exploiting of a pandemic for a “broader good.”


    If one reads Moderna investor disclosures as late as December 2019, they included material a couple of months forward (the report isn’t filed until the end of Quarter 1, 2020) with the company acknowledging all of the risks associated with the novel technology. Just find the 2019 annual report and read it carefully.


    Yes, of course, mRNA initiatives were ongoing for the past couple of decades but these products remained highly experimental, and early on in the science when considering commercialization. When it came to commercialization, Moderna essentially disclosed to investors “we don’t know what we don’t know so investors be aware.” Importantly, while the entire mainstream press, government agencies, and the WHO bash anyone who reports vaccine injuries, this author assures all who bother to read this that they are real. TrialSite estimates anywhere from half a million to 2 million people in the U.S. alone are having material residual problems associated with the COVID-19 vaccines. We suspect anywhere between 10,000 and 30,000 people died from reactions that likely were associated with the countermeasures.


    Of course, the vaccines were developed to induce antibodies and protect people from the SARS-CoV-2 surges, and they worked for a while. But they were not perfect, and it’s not right that government, industry, and academic medicine are running away from their accountability.


    The Real Agenda

    One cannot let any good crisis go to waste. Fauci (and to be fair a lot of others) capitalized on this pandemic for innovation, all to drive massive economic development and ultimately wealth accumulation for systemic players. Of course, the target outputs are products that save humanity but that’s secondary. First, follow the money—in the case of COVID-19, $5.5 trillion and counting.


    Fauci likely won’t have to save his legacy. That’s because there is too much societal power and money backing this whole narrative, that COVID-19 vaccines “saved innumerable lives and helped to achieve early partial pandemic control” in his own words in the recently published piece.


    We’ll give Fauci partial credit for the first point, that the vaccines in surges, if administered correctly, helped soften the sharp and deadly edge of the pandemic’s knife….but on the latter point, that it helped stop the control of the pandemic? Here is where Anthony reveals his true station—a bureaucratic medical hustler. If he knew the science, he would have known in the first place that the vaccines would not be able to keep up with a mutating RNA coronavirus; that they would not be sterilizing, and that they would lack breadth and durability. TrialSite called that out long ago. How come we know this and not the apex research institute of the world?


    ‘Deficient’ Vaccines

    In the recent article, Fauci and colleagues go on to declare that the COVID-19 vaccines are “deficient,” now conveniently remembering the science behind these viruses. Much like influenza and the common cold, coronaviruses mutate, which is why they have had such a tough time coming up with controlling vaccines in the first place. Again, what happened to that scientific knowledge in early 2020?


    In this way, his words in his recent paper are meant to explain away and rationalize the largely failed vaccination program. We say this not only because of the substantial limitations of the accelerated countermeasures but also for how the pandemic was managed. Companies like Pfizer, backed by the government serving as the promotional engine, the legitimizer, shut down any front-line initiatives in the clinic early on to use repurposed medicines for example to help save lives. The IMAC protocol serves as a great example.


    A pharmacist came up with a lifesaving protocol during the summer of 2020 inclusive of blood thinners and steroids among other elements. A small local Florida newspaper reported on the matter and then TrialSite published a piece that went viral, worldwide. Hundreds of thousands of people read the article, which led to the shutting down of the protocol at an incredibly deadly time with no vaccines available.


    While the federal government’s various agencies are quick to calculate with the help of academia how many lives they saved with the vaccines (albeit in temporary surges) they don’t calculate how many lives they terminated with their policies stopping early on efforts to help treat people.


    The pharmacist that came up with the protocol lost her job. We have been told by insiders that due to contracts with Pfizer that the health system’s employees couldn’t do anything to save lives that the pharmaceutical company would have deemed competitive with the vaccine which at the time was in clinical trials. Of course, this kind of conduct done in a pandemic, is highly unethical in this author’s opinion borders on the criminal.


    A Front Man?

    Ultimately, Fauci served as a frontman for the medical-research complex, helping to direct which products would have a better probability of clearing largely NIH-funded clinical trials.


    It’s important to note that Fauci, however, isn’t some supervillain. He was merely a bureaucrat, albeit a powerful one. But he didn’t have the power to oversee the entire pandemic response apparatus, its vast federal division of labor, with its questionable countermeasure vaccines and therapeutics. He was a spokesperson, a figurehead, although one wielding clout within the federal bureaucracy.


    Notably, the pandemic response reflected systemic attributes, the result of an unfolding way of life in America, and for that matter, the West. An apex research institute such as the NIH, or even WHO become ever more tied into industry because that’s how drugs get developed. But industry depends on investors, higher stock prices, lots of sales, and growth. Pharmaceutical companies cannot move into novel products that don’t produce substantial returns or profits.


    Fauci, a child of this system, knows no other way of life. Of course, generic companies could have been mobilized with the $5.5 trillion in taxpayer money that was redistributed during the pandemic—but that’s for another day. The problems encountered during the pandemic are systemic and require broad reforms including a redirection of substantial public investment in true health care—meaning proactive ways to help us get healthier, as the various indicators suggest we are getting sicker as a people in America and in many other developing and developed places. In some ways, wealth and convenience augmented by technology make us worse off from a health point of view. The pharmaceutical companies are not at fault for this, but rather merely seek to capitalize on the ensuing market demands.


    Did Fauci assume that the COVID-19 vaccines would be durable knowing that the underlying virus would continuously mutate (because that’s what coronaviruses do)? Or did he somehow forget his basic science for COVID-19, pushing investigational products with limited shelf life, as part of a broader innovation agenda? It’s for you, the TrialSite reader, to figure out.


    Call to Action: See the full article here.

    Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses
    Despite the successful deployment of vaccines during the SARS-CoV2 pandemic, viruses replicating in the respiratory mucosal environment continue to present a…
    www.cell.com

  • A New (Old) Drug Joins the COVID Fray, and Guess What? It Works

    A New (Old) Drug Joins the COVID Fray, and Guess What? It Works
    Approving this drug would double our COVID treatment options, says Dr Perry Wilson in this week's Impact Factor.
    www.medscape.com


    At this point, with the monoclonals found to be essentially useless, we are left with remdesivir with its modest efficacy and Paxlovid, which, for some reason, people don't seem to be taking.


    Part of the reason the monoclonals have failed lately is because of their specificity; they are homogeneous antibodies targeted toward a very specific epitope that may change from variant to variant. We need a broader therapeutic, one that has activity across all variants — maybe even one that has activity against all viruses? We've got one. Interferon.


    The first mention of interferon as a potential COVID therapy was at the very start of the pandemic, so I'm sort of surprised that the first large, randomized trial is only being reported now in The New England Journal of Medicine.


    Before we dig into the results, let's talk mechanism. This is a trial of interferon-lambda, also known as interleukin-29.


    The lambda interferons were only discovered in 2003. They differ from the more familiar interferons only in their cellular receptors; the downstream effects seem quite similar. As opposed to the cellular receptors for interferon alfa, which are widely expressed, the receptors for lambda are restricted to epithelial tissues. This makes it a good choice as a COVID treatment, since the virus also preferentially targets those epithelial cells.


    In this study, 1951 participants from Brazil and Canada, but mostly Brazil, with new COVID infections who were not yet hospitalized were randomized to receive 180 µg of interferon lambda or placebo.


    This was a relatively current COVID trial, as you can see from the participant characteristics. The majority had been vaccinated, and nearly half of the infections were during the Omicron phase of the pandemic.


    https://www.nejm.org/doi/full/10.1056/NEJMoa2209760


    Vitamin D and chronic hepatitis C: effects on success rate and prevention of side effects associated with pegylated interferon-α and ribavirin

    Vitamin D and chronic hepatitis C: effects on success rate and prevention of side effects associated with pegylated interferon-α and ribavirin
    Chronic hepatitis C (CHC) is one of the most common causes of liver diseases worldwide, affecting 3% of the world population and 3 to 4 million people acquire…
    www.ncbi.nlm.nih.gov

  • NIAID Admits COVID-19 Vaccine "Scientific and Public Health Failure

    NIAID Admits COVID-19 Vaccine "Scientific and Public Health Failure"
    A new article written by Directors of the National Institute of Allergy and Infectious Diseases (NIAID), coauthored with Tony Fauci and recently published in a…
    www.trialsitenews.com


    A new article written by Directors of the National Institute of Allergy and Infectious Diseases (NIAID), coauthored with Tony Fauci and recently published in a scientific journal, admitted that the COVID-19 vaccines are a failure!


    "Durably protective vaccines against non-systemic mucosal respiratory viruses with high mortality rates have thus far eluded vaccine development efforts."


    "Past unsuccessful attempts to elicit solid protection against mucosal respiratory viruses and to control the deadly outbreaks and pandemics they cause have been a scientific and public health failure that must be urgently addressed. "

    Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses: Cell Host & Microbe.

    Rethinking next-generation vaccines for coronaviruses, influenzaviruses, and other respiratory viruses
    Despite the successful deployment of vaccines during the SARS-CoV2 pandemic, viruses replicating in the respiratory mucosal environment continue to present a…
    www.cell.com

    NIAID's acknowledgement of the failure to contain the coronavirus with vaccines verifies what I predicted in 2021:


    "Considering the failure to find a cure for coronavirus infections in the common cold after many decades of research, the potential for newly developed vaccines to eliminate the virus and its variants does not portend well."

    Sodium Toxicity in the Nutritional Epidemiology and Nutritional Immunology of COVID-19.

    Sodium Toxicity in the Nutritional Epidemiology and Nutritional Immunology of COVID-19
    Dietary factors in the etiology of COVID-19 are understudied. High dietary sodium intake leading to sodium toxicity is associated with comorbid conditions of…
    www.mdpi.com


    ivermectin - Search Results - PubMed
    ivermectin - Search Results - PubMed
    pubmed.ncbi.nlm.nih.gov

  • WE WON: Government commits to publishing £248m missing Covid contracts after breaching transparency guidelines


    Back in March 2021, former Prime Minister Boris Johnson, told Parliament that details of all Covid contracts were now “on the record”. A month later, Cabinet Minister Julia Lopez, claimed “all historical Covid-related contracts” had been published.


    Neither statement was true.


    Last month, we took the first formal step in legal proceedings against the Cabinet Office for its three-year failure to publish the 29 contracts awarded to suppliers as part of the Government’s controversial ‘Ventilator Challenge’ programme.


    In total, £277m was spent by the Cabinet Office procuring ventilators during the pandemic with an eye-watering £143m going to waste.


    The Government has now admitted it breached its own transparency policy in what it calls a “regrettable oversight.” And it has committed to publishing the missing contracts by 28 February 2023. You can read the full response to our Pre-Action Protocol letter here.


    In its response to us, the Cabinet Office said:

  • Splanchnic Vein Thrombosis with COVID-19 Illness and Vaccination

    Abdominal Catastrophe Carries High Mortality for Both Victims

    Splanchnic Vein Thrombosis with COVID-19 Illness and Vaccination
    Abdominal Catastrophe Carries High Mortality for Both Victims
    petermcculloughmd.substack.com


    By Peter A. McCullough, MD, MPH


    Over the the course of the pandemic I received many calls from patients and their families. One of the most difficult symptoms to evaluate over the phone is abdominal pain. Most patients whether at home or in the hospital need a doctors exam to assess acuity, tenderness, peritoneal signs, distension, and incipient gastrointestinal bleeding and or perforation. Because the Spike protein on the surface of SARS-CoV-2 causes blood clotting, most venous thromboembolic syndromes are seen in both COVID-19 patients and those who took the vaccines. It is my experience that the highest risk patients are those who have cumulatively been exposed to the Spike protein via multiple injections and one or more occurrences of COVID-19 illness

    Zheng and colleagues performed a systematic review of the literature and found 123 cases reports of splanchnic vein thrombosis, or blood clots in the veins that drain the intestines. This can be a catastrophe causing bowel necrosis, distension, bleeding, gastrointestinal perforation, and death. There were 75 cases in those who had acute COVID-19 and I anticipate most where critically ill in the hospital with an overall mortality rate of 14%. Alarmingly, there were 58 cases of the same problem in those who were vaccinated, presumably well at home and the mortality rate was 25%.

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