Fm1 Member
  • Member since Mar 28th 2016
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Posts by Fm1

    Great find: One more herb that works! Whether you (stomach!) can withstand the high dose 80mg/kg is an other question!

    A little tumeric will take care of that and make it taste a whole hell of a lot better

    Nigella sativa L. (Black Cumin): A Promising Natural Remedy for Wide Range of Illnesses

    Oxidative stress and an intensification in the levels of free radicals are amongst the foremost central markers associated with several progressive pathological conditions, including neurological disorder, cancer, aging, and endocrine illness [36]. To date, there has been a growing importance in the therapeutic option of medicinal plants as natural antioxidants. Among the various naturally occurring medicinal plants, N. sativa has been reported for its effective antioxidant activities of in- vivo and in- vitro studies [37]

    Maybe a treatment for long hualers

    Doc Richard will like this

    Nigella sativa study for covid treatment

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    Covid Drugs From Lilly, Regeneron Raise Access, Timing Concerns…se-access-timing-concerns

    Though the U.S. has spent hundreds of millions of dollars to snap up the antibody treatments, they will be rationed due to limited supplies. Officials are working to establish sites to infuse the medications to patients with mild to moderate disease who had until recently been advised to stay home during an unprecedented surge in cases.

    Ethnicity and clinical outcomes in COVID-19: A systematic review and mmeta-analysis…-5370(20)30374-6/fulltext

    Individuals of Black and Asian ethnicity are at increased risk of COVID-19 infection compared to White individuals; Asians may be at higher risk of ITU admission and death. These findings are of critical public health importance in informing interventions to reduce morbidity and mortality amongst ethnic minority groups.

    Maybe a vitamin D deficenccy???

    Safety and efficacy of inhaled nebulised interferon beta-1a (SNG001) for treatment of SARS-CoV-2 infection: a randomised, double-blind, placebo-controlled, phase 2 trial…-2600(20)30511-7/fulltext

    Patients who received SNG001 had greater odds of improvement and recovered more rapidly from SARS-CoV-2 infection than patients who received placebo, providing a strong rationale for further trials.

    a little off topic but interesting

    EU fines drug makers for keeping cheap medicine off market…63e932355b7e6e716339b4de3

    EU antitrust commissioner, Margrethe Vestager, said that Teva pharmaceuticals and Cephalon, a company it later acquired, must pay 60.5 million euros ($72 million) for agreeing between themselves to delay for years the launch of Teva’s cheaper version of Cephalon’s blockbuster Modafinil. In return for the delay, Teva got beneficial side deals and some payments.

    Oregon mink farm has COVID-19 outbreak after advocates warned of danger in state…=en-US&gl=US&ceid=US%3Aen

    Outbreaks in farmed mink have been reported in several U.S. states and countries. Earlier this month Denmark announced it would kill all 17 million of the mink raised there after confirmation that 12 people had been infected with a mutated strain of COVID-19 that had spread from mink to humans. That strain has not been found elsewhere.

    The full cholesterol study

    HDL-scavenger receptor B type 1 facilitates SARS-CoV-2 entry

    Responsible for the ongoing coronavirus disease 19 (COVID-19) pandemic, severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infects host cells through binding of the viral spike protein (SARS-2-S) to the cell-surface receptor angiotensin-converting enzyme 2 (ACE2). Here we show that the high-density lipoprotein (HDL) scavenger receptor B type 1 (SR-B1) facilitates ACE2-dependent entry of SARS-CoV-2. We find that the S1 subunit of SARS-2-S binds to cholesterol and possibly to HDL components to enhance viral uptake in vitro. SR-B1 expression facilitates SARS-CoV-2 entry into ACE2-expressing cells by augmenting virus attachment. Blockade of the cholesterol-binding site on SARS-2-S1 with a monoclonal antibody, or treatment of cultured cells with pharmacological SR-B1 antagonists, inhibits HDL-enhanced SARS-CoV-2 infection. We further show that SR-B1 is coexpressed with ACE2 in human pulmonary tissue and in several extrapulmonary tissues. Our findings reveal that SR-B1 acts as a host factor that promotes SARS-CoV-2 entry and may help explain viral tropism, identify a possible molecular connection between COVID-19 and lipoprotein metabolism, and highlight SR-B1 as a potential therapeutic target to interfere with SARS-CoV-2 infection.

    Covid: Free Vitamin D pills for 2.5 million vulnerable in England…=en-US&gl=US&ceid=US%3Aen

    Health officials say that even in a normal winter, everyone should take 10 micrograms of Vitamin D a day between October and March - and it's particularly important this year because of coronavirus.

    Scottish and Welsh governments, and Northern Ireland's Public Health Agency issued similar advice during lockdown.

    Ignoring mild symptoms of COVID-19 can lead to fatal complications'…=en-US&gl=US&ceid=US%3Aen

    The hospital said that it has been receiving patients with high grade fever, severe body and muscle ache, stroke, leg thrombosis, lung fibrosis and cardiac involvement, the classic manifestations of Covid-19.

    The clinical investigation of thirty such patients revealed that they never underwent the test to detect the virus despite developing mild symptoms of the disease thinking that the symptoms would go away on their own.

    If you still won’t wear a coronavirus face mask after seeing this, you’re insane…=en-US&gl=US&ceid=US%3Aen

    Rather than becoming a simple tool to prevent the spread of the novel coronavirus, face masks have become highly controversial. An anti-mask movement fueled by politics rather than science gained traction in the US and abroad, with some people becoming convinced that face coverings don’t help to stop the spread. Some went even further, claiming that masks will prevent oxygen from reaching the body. Worst of all, some likened masks to oppression and found all sorts of reasons to avoid wearing masks in public.

    Looks like sponsored by the statines mafia. Reporters mix up receptors with cholesterol... In fact Germans have a genetically based higher cholesterol level and show no correlation with this nonsensical claim...

    I guess the next paper will be about red hair or long toe nails ...

    I read that study, germans drink more go ffigure and americans are out of shape. Doesn't explain this studys results

    Decline in SARS-CoV-2 Antibodies After Mild Infection Among Frontline Health Care Personnel in a Multistate Hospital Network — 12 States, April–August 2020

    Once infected with SARS-CoV-2, most persons develop virus-specific antibodies within 2–3 weeks (2,3). Serology tests are now being used widely in seroprevalence studies to understand patterns of viral spread, cumulative incidence of SARS-CoV-2 infection, and pandemic trajectory (4–6). Further, serologic testing has been proposed as a way to identify persons who might have developed immunity through a previous infection. Understanding how rapidly SARS-CoV-2 antibody levels decline after seroconversion is critical for interpreting serology results. A limited number of studies have found declines in SARS-CoV-2 antibody levels over time (7–9), but the frequency and timing of seroreversion (the decline in antibody levels below the positivity threshold after initial seroconversion) remains largely unknown.

    Covid-19: What makes coronavirus the most potent pathogen since Spanish Flu…=en-US&gl=US&ceid=US%3Aen

    The human immune system did not have an idea how to nail down the new pathogen. Further, the virus underwent a key mutation that made it more infective.

    This mutant variety, known as D614, was first identified in China, where Covid-19 pandemic started, and then in Europe. It was later found to be spreading fast in the US, Canada and also India.

    Mutation is an error or need-based genetic evolution. Virus makes its copy once inside a host. While making copies of virus, error occurs at times or virus’s gene undergoes a change, making the new variety duller or smarter. D614 made the novel coronavirus smarter and faster in spread.

    Covid latest: Cholesterol is the key factor for severe covid infections says latest study…creased-risk-covid-19/amp

    The novel coronavirus has been known to affect people in a number of different ways with some experiencing a severe infection and others not. Now, a recent study suggests the amount of cholesterol a person is carrying may be the key factor into the severity of COVID-19 infection.