THHuxleynew Member

(Quote from oldguy)


Sounds as though the side effects might be difficult to manage in a hospital setting...

https://www.biorxiv.org/content/10.1101/2020.03.31.018556v1

Possible severe toxicity of HCQ with Metformin. In animal studies, so may not translate to huamns, but a real reason to be cautious.

This is a fascinating reanalysis of the famous (infamous?) Gautret et al HCQ data.

It shows, precisely, why that study does not lead to clear conclusions using a number of different Bayesian analyses. The clever thing is that the different analyses show…

(Quote from seven_of_twenty)


In addition, the age profile (for most such countries) is skewed towards young people: in many of these countries there are many fewer old people, and therefore many fewer noticed cases - and as above, those are often not…

(Quote from JedRothwell)

There are as yet no specific data but it does seem as if the beneficial immune response to COVID-19 virus varies between individuals. For no apparent reason, siblings or other members of an entire family die of it while the…

HCQ and magic bullets.

Some people, perhaps following the US presidency, are taking a black and white view of HCQ: either it is a magic bullet, or it is worthless. The truth is often somewhere in between.

(Quote from axil)


Zinc deficiency is not that common.

https://www.health.com/nutrition/zinc-deficiency

I have to say that I, in these locked in times, am adding zinc supplements to my diet, as well as obligatory far Northern winter vitamin D, since it has…

(Quote from seven_of_twenty)


Seems pretty fair. One thing it does not note is that HCQ (and many other treatments) do not have uniform effectiveness when taken at different times. If you factor in the hypothesis that HCQ is most effective given in the…

(Quote from Shane D.)


Shane, you are now on the wrong side of this argument - inconsistent with your earlier "get em back to work" views.

If you want the earliest, longest return to something close to normality this is one of the ways it can happen.…

(Quote from sam12)


The only thing I said on my JONP is I read his legal teams filing saying he is quarantined in Milan. Is that not the unequivocal truth? How can it be "as I see it?"

(Quote from Wyttenbach)


Nope. Everyone dies just once.

(Quote from Zeus46)


Trump on distancing (satire - but undoubtedly and apolitically true):

Issuing a new distancing guideline on Wednesday, Donald Trump said that he was now practicing distancing from all of his previous statements about the coronavirus.
…

Wyttenbach
It would take too long but basically your inference is wrong. Virtually everything you post is wrong or you draw the wrong conclusions. Statins emphatically do not cause dementia and they certainly do reduce initial and repeat myocardial…

(Quote from seven_of_twenty)


In addition, that study was dealing with patients already far advanced in the disease. It would not be surprising if a number of treatments effective if taken from early stages are not effective at the end. So, even if it were…

(Quote)

COMPLETE BULLSHIT!

It is irritating to read crap like that, obviously written without the slightest attempt to find the facts. It took me about thirty seconds to locate this:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078755/

This is a metastudy…

(Quote from Cydonia)

My engineering is fine. You won’t see me adding 3 extra junctions to my thermocouples, and my calorimeter can detect my breath and body heat when I stand in front of it.

These are public documents, but if you want to blame someone,…

Video review (looks a respectable source)

https://www.microbe.tv/twiv/tw…Virology+-+MP3+Edition%29

(Quote from Dr Richard)


the best (really the only) definite evidence published so far, and although not yet formally peer reviewed you will note it has been properly reviewed, is this well conducted 31 + 31 randomised control study:

…

(Quote from RobertBryant)


We need batman, robin, and .... Batgirl to deal with this!

Scary things - ultra-virulent bat virusses.

But, to be fair, 40% of people who are infected have minimal symptoms so their immune systems seem good enough at getting rid…

For those who wish to follow the latest COVID-19 (non-peer-reviewed) preprints on medRxiv.org and bioRxiv.org, these are on the URL: https://connect.biorxiv.org/relate/content/181

A few published in the last two days that I found interesting were ---

…