The Totally Civil Covid Thread. (Closing 31/05)

  • Hmmm just another coincidence in a very very long line of coincidence?


    Study finds lung cells regulate SARS-CoV-2 infection


    Study finds lung cells regulate SARS-CoV-2 infection
    Researchers at UC Berkeley’s Hsu Lab identified human lung proteins that can either promote or restrict infection from SARS-CoV-2.
    www.dailycal.org


    After manipulating one gene in each cell and exposing the cells to the virus, the researchers waited to see which cells would survive, according to campus assistant specialist and lead study author Sylvia Sarnik. They then took the surviving cells and sequenced the genes to discover which knocked-out gene helped the cell survive.


    “Mucins are important for maintaining homeostatic conditions, such as detecting injury and surface stresses,” Biering said. “We found many different mucin proteins were important for restricting the virus.”


    Vitamin D regulates immunoglobulin mucin domain molecule-4 expression in dendritic cells

    https://onlinelibrary.wiley.com/doi/abs/10.1111/cea.12894

  • Track stars are dropping like fly's

    And lot's of other athletes.

    For sure. The average number of athlete sudden deaths per year was about 70. Since the fall of 2021, it has been averaging about that PER MONTH according the the website below.



    The above was taken from

    1218 Athlete Cardiac Arrests, Serious Issues, 816 Dead, After COVID Injection - Real Science
    It is not normal for young athletes to suffer cardiac arrest or death while playing sport, but most of these come shortly after a COVID shot.
    goodsciencing.com

  • Mandating Covid vaccines for children is foolish and greed driven


    SARS-CoV-2 Infections in Icelandic Children

    Close Follow-Up of All Confirmed Cases in a Nationwide Study


    SARS-CoV-2 Infections in Icelandic Children: Close... : The Pediatric Infectious Disease Journal
    he pandemic and offers more accurate information of the number of truly infected children in a nationwide study. Material and methods: All children with…
    journals.lww.com


    Abstract

    Introduction:

    Children are less likely to acquire SARS-CoV-2 infections than adults and when infected, usually have milder disease. True infection and complication rates are, however, difficult to ascertain. In Iceland, a strict test, trace and isolate policy was maintained from the start of the pandemic and offers more accurate information of the number of truly infected children in a nationwide study.


    Material and methods:

    All children with positive PCR for SARS-CoV-2 infections from February 28, 2020 to August 31, 2021 were followed up through telephone consultations for at least 14 days and their symptoms were registered. Symptom severity and duration were categorized based on age groups and the source of infection was registered.


    Results:

    A total of 1749 children were infected with SARS-CoV-2 in 3 waves of infections. All waves had similar disease severity whereas the incidence was 5-fold higher in the third wave (3.5 vs. 0.73/1000 children/month). No children had severe symptoms, 81 (4.6%) had moderate symptoms, 1287 (73.9%) had mild and 374 (21.5%) were asymptomatic. Symptoms from upper (n = 839, 48%) and lower respiratory tract (n = 744, 43%) were most common. Median duration of symptoms was 5 days and adolescents had a higher risk of prolonged duration [OR:1.84 (1.39–2.43)]. Nineteen (1.1%) children needed medical attention, but no child was hospitalized. The source of infection was a household member in 65% of cases.


    Discussion:

    During the first 3 waves of the pandemic, SARS-CoV-2 infections in Icelandic children were mild and none were hospitalized. The most common symptoms were respiratory symptoms followed by fever, headache and tiredness. This study helps shed light on true complication rates of children with confirmed SARS-CoV-2 infection

  • Discussion:

    During the first 3 waves of the pandemic, SARS-CoV-2 infections in Icelandic children were mild and none were hospitalized.

    In Switzerland nobody healthy age < 30 died from CoV-19. The few victims have all been on cancer chemo or severely ill

    .https://www.covid19.admin.ch/d…iologic/death?time=phase2


    Be also aware that starting with October 2021 all hospital patients have been tested for Omicron and thus many deaths are with no from...

  • The vaccine reduces severity for people who are most susceptible to severity so dosing 10,000 healthy people to save one life and opening up 9,999 to adverse events doesn't make sense.

    FM1 -


    You choose to ignore the experts, and also the independent experts, who show the balance of risk and only allow vaccines when it looks positive.


    It is of course your privilege to think you know better than them, or that they are all guilty of manslaughter.


    We will not see eye to eye on this since I think your understanding of how to interpret scientific data, whenever we have discussed it, is less good even than mine: and my understanding is less good than that of the many experts. I am making that judgement based on specific details. I am not uncritically assuming someone called an expert has good understanding. But equally if my (partial) understanding led me to think everyone had got something major wrong - I would spend a lot of time trying to work out why I had got something wrong myself.


    There is a proper debate about exactly what are the risks - but COVID is a nasty disease even for those who are young. The vaccines are very safe (though not as safe as our safest vaccines). I would be happy for you to post credible evidence comparing risks. For most people, not relatives of Mark U, it is a no brainer. (A friend of mine, about my age, perfect healthy, caught COVID, had a mild disease, and has been left with 1.5 year long long COVID ever since). Omicron may be milder but that is by a small amount - many people are still getting long COVID. The perception that it is milder is mostly driven by the fact that now almost everyone is vaccinated, and most have already had COVID once. The level of protection in the population is much higher now. But that protection does not last forever, which is why governments worried about hospital demand push vaccination (and for those at greater risk booster vaccination). In the UK, at least, no-one is forced to be vaccinated.


    For your view to work you have to assume the whole medical establishment is deliberately underestimating vaccine risks. The doctors I know are far to independent to do that: and teh scientists I know care about truth, not politics.


    Maybe these things are different in the US?


    But, even so, other countries (e.g. the UK) have similar vaccination policies. No-one thinks they stop infections - in fact the Uk has given up any pretence of wanting to stop infections. They are pushed because they reduce severe disease and therefore the politically crucial hospital demand. Every UK doctor and politician knows that is vital.


    So you have to suppose some weird conspiracy. I just don't get it.


    THH

  • Mandating Covid vaccines for children is foolish and greed driven

    It sounds to me, like much of the US health system, broken.


    And we can all see from FM1's reaction that it is counterproductive, causing people who might otherwise look at the data mopre openly to take an anti-vaccination stand on the basis of obviously flawed interpretations from fringe antivaxxer websites such as TSN.

  • For sure. The average number of athlete sudden deaths per year was about 70. Since the fall of 2021, it has been averaging about that PER MONTH according the the website below.

    The two streets I go to that are known for aged walkers seems most of them died after a stab or two. So its still very low numbers used.- they drop like fly's.

    i had my helicopter ride but made it.

    seems we are in the musky rules when sent to the ER to do anything they want if you sign the paper.

    just like today's banks, you don't get service without signing.

    bump in the road imminent.

    .

  • No children had severe symptoms, 81 (4.6%) had moderate symptoms, 1287 (73.9%) had mild and 374 (21.5%) were asymptomatic.

    The sample here was approx 1741 children.


    MIS-C rates from COVID are 316 per 1,000,000 infections https://www.acc.org/Latest-in-…hings-to-Know-About-MIS-C


    That is 0.0316% - so you would not expect any MIS-C cases from this small sample (and indeed none was diagnosed).


    Nevertheless MIS-C affects 1 in 3000 children with COVID and if you are a parent of a child so affected you will be very very sorry you did not vaccinate your child and reduce the risk.


    THH

  • The conspiracy is in thinking hospitals will be over run with patients. That was only true during the first surge of the pandemic when world leaders ordered lockdowns effectively taking 2/3 of your healthcare system out of the loop. Since reopening and allowing patients to see primary care the concern of over burdening hospitals is well it's bullshit!

  • More crap from hux the huxster. In children you reduce the risk by less than 15%. And only over a small amount of time as efficacy drops faster than adult dose.

  • More antivaxxer propaganda from Mark U.


    Myocarditis and pericarditis in athlete is a serious matter. And they can drop dead.


    The issue is what is the cause of this? COVID? Or COVID vaccine?


    COVID-Related Athletic Deaths: Another Perfect Storm?
    Athletes of all ages and sex can suffer poor health, including cardiac conditions, and some may die during training or competition. While athletes are often…
    www.frontiersin.org


    From a cohort study of 1,597 U.S. university competitive athletes following COVID-19 infection, 37 athletes (2.3%) were diagnosed with clinical and subclinical myocarditis. Indeed, it has been known for some time that physical activity can increase the risk of death in those with myocarditis and other cardiovascular conditions. For example, in an autopsy study of US Air Force recruits with SCD, physical activity was a risk factor with unrecognized myocarditis as the most common suspected underlying factor (Phillips et al., 1986). Numerous other studies demonstrate similar results and show that the prevalence of signs on CMR imaging of myocarditis is in the range of 1–3% in athletes following positive COVID-19 test results (Udelson et al., 2021).

    In addition to myocarditis, pericarditis, inflammation of the pericardium, has also been observed in post-COVID infected patients (Brito et al., 2021). In 54 previously healthy college athletes who tested positive for COVID-19, Brito et al. (2021) found that more than a third showed imaging features of pericardial inflammation. In particular, severe cases of myocarditis and pericarditis can result in chronic heart failure or death and are therefore important public health concerns (Husby et al., 2021). While the biological mechanisms are not yet clear, the same adverse events were attributed to use of the smallpox vaccine in adults (Halsell et al., 2003).


    Now, COVID vaccines can also cause myocarditis, of course. But we know the rate at which that happens, and it looks a lot lower than the COVID-induced myocarditis.


    Note that this myocarditis will often not be diagnosed, but obviously can increase risks of problems for people taking intense exercise after COVID in an attempt to get fit again.


    Researchers Investigate What COVID-19 Does to the Heart
    This Medical News article discusses reports of myocardial injury and myocarditis among patients with COVID-19.
    jamanetwork.com


    The effects of cardiac inflammation in COVID-19 are wide-ranging and, for some, appear to be the infection’s main feature. In March, physicians in Italy determined that inflammation of the heart muscle and sac, known as myopericarditis, was likely behind extreme fatigue in an otherwise healthy 53-year-old woman with a positive SARS-CoV-2 test who had mild respiratory symptoms and fever a week earlier.


    Experts haven’t reached consensus on how long viral myocarditis takes to resolve, in part because sophisticated imaging tools and protocols for accurately diagnosing it are relatively new; in addition, the duration of clinical symptoms may not match serological or imaging biomarkers. This unknown has made it hard to interpret some findings from recovered patients.


    A study published in May, for example, examined 26 patients discharged from a Wuhan hospital after recovering from moderate to severe COVID-19. The patients had had symptoms including chest pain and palpitations for a median of 47 days by the time they underwent cardiac magnetic resonance (CMR) imaging. Fourteen patients had edema—fluid retention, which is the key sign of active inflammation on CMR. Many of them also had indicators of scarring and decreased right ventricle function.


    The most alarming report to suggest lingering heart injury appeared in July in JAMA Cardiology. Researchers in Germany examined data from 100 patients thought to have recovered based on a negative nasal swab. Two to 3 months after their COVID-19 diagnosis, 60 of the individuals had indications of myocardial inflammation on CMR, and even more had elevated troponin levels. Three individuals with severe abnormalities underwent biopsies that confirmed active inflammation in their heart muscle tissue. Compared with a control group, the recovered patients had greater left ventricular volume and lower ejection fraction, signs that their hearts were enlarged and pumping less efficiently.


    A few things besides the frequency of aberrations were cause for concern. Unlike the study published in May, two-thirds of patients in this report didn’t require hospitalization, and some were even asymptomatic. What’s more, the patients were relatively young (49 years old, on average), and their COVID-19 severity, preexisting health conditions, and time since diagnosis didn’t affect their likelihood of having an abnormal heart scan.


    The results suggested that scores of otherwise healthy people who recovered from COVID-19—even those who didn’t get very sick—could have potentially harmful inflammation smoldering in their hearts months later.



    I am not suggesting that we have a reliable figure for COVID-induced myocarditis - but the figures we do have indicate a problem a lot higher than that from vaccination.


    I'd welcome a proper comparison.


    THH

  • And... here we go


    COVID-19 infection more likely than vaccines to cause rare cardiovascular complications — Nuffield Department of Primary Care Health Sciences, University of Oxford


    Unfortunately that pop account does not directly link the paper nor does it give clear figures for under-40s.


    Incidence, risk factors, natural history, and hypothesised mechanisms of myocarditis and pericarditis following covid-19 vaccination: living evidence syntheses and review
    Objectives To synthesise evidence on incidence rates and risk factors for myocarditis and pericarditis after use of mRNA vaccination against covid-19, clinical…
    www.bmj.com


    living review of myocarditis rates after vaccination stratified by age.


    For the 12-15 and 16-19 male age groups, the adjusted rates per million were 601 (257 - 1,406) and 561 (240 - 1,313)



    Risk of Myocarditis from COVID-19 Infection in People Under Age 20: A Population-Based Analysis - PubMed
    Myocarditis (or pericarditis or myopericarditis) from primary COVID19 infection occurred at a rate as high as 450 per million in young males. Young males…
    pubmed.ncbi.nlm.nih.gov


    rates of myocarditis after covid in young people:


    In The Lancet, Hui-Lee Wong and colleagues10
    robustly replicate the previous findings using large-scale US health plan claims data. Notably, the new study uses data from four health plan databases, covering more than 100 million individuals. Of these, 15 148 369 were aged 18–64 years and registered to have received a COVID-19 mRNA vaccine (53·1% male and 13·0% aged 18–25 years). Similar to previous studies, Wong and colleagues10
    observed higher than expected rates of myocarditis (and pericarditis, a closely related clinical presentation), specifically in individuals younger than 35 years, with the highest risk among men aged 18–25 years after their second COVID-19 mRNA vaccine dose. The absolute risk of myocarditis or pericarditis, calculated as the incidence rate within 1–7 days of vaccination, for men aged 18–25 years after a second vaccination dose was 2·17 (95% CI 1·55–3·04) cases per 100 000 person-days for the Moderna vaccine, mRNA-1273, and 1·71 (1·31–2·23) cases per 100 000 person-days for the Pfizer-BioNTech vaccine, BNT162b2. Furthermore, the study supports the previous finding that the association is principally short term. The data indicate that this adverse event primarily occurs within 1–7 days of vaccination, because a longer duration of follow-up attenuated the association. Although not significantly different, the study found a tendency towards a higher risk of myocarditis after vaccination with mRNA-1273 in a head-to-head comparison with BNT162b2 (with an adjusted incidence rate ratio of 1·43 [95% CI 0·88–2·34] among men aged 18–25 years). Similar findings of a more pronounced risk of myocarditis after mRNA-1273 in comparison with BNT162b2 have been observed in other large observational studies.3–5,9


    The absolute risk of myocarditis or pericarditis, calculated as the incidence rate within 1–7 days of vaccination, for men aged 18–25 years after a second vaccination dose was 2·17 (95% CI 1·55–3·04) cases per 100 000 person-days for the Moderna vaccine, mRNA-1273, and 1·71 (1·31–2·23) cases per 100 000 person-days for the Pfizer-BioNTech vaccine, BNT162b2.



    For 18-25 years per vaccination event this is (for Moderna, the worst): 2.17*7 / 100,000 = 150 per million.


    So the rates are comparable with COVID infection - for young people - but a bit lower. 4 X lower from this comparison but I do not trust that - you would need much more careful review of all the figures and also an adjustment for the different age cohort. Still this makes it very likely that COVID is a significantly higher risk even than Moderna (the worst) vaccine.


    For everyone else (> 25) the vaccine myocarditis rates go down faster than the COVID myocarditis rates.


    So - if you are an athlete -0 your best strategy is not to be vaccinated and never catch COVID. Good luck with that one!


    One other factor - you can choose when you are vaccinated and do this with lots of time before your next competitive event - which would help given that the vaccine-induced myocarditis is short-term.



    I have not proven beyond doubt that vaccination is a better strategy than getting COVID for young athletes unworried about long COVID and only interested in the effects of myocarditis.


    But it seems likely.


    THH

  • And more evidence. The professionals who treat young sports people do not see any risk from vaccines:


    Reports of Sudden Deaths Among Athletes After COVID-19 Vax Are ‘Misinformation’
    Sports cardiologists said they aren’t aware of any credible cases of athletes dying from shot-related adverse effects.
    www.tctmd.com


    “I think those links are completely false information,” said Jonathan Drezner, MD (UW Medicine Center for Sports Cardiology, Seattle), editor-in-chief of the British Journal of Sports Medicine. “Many of those cases have other diagnosed conditions and even occurred before the pandemic started—so there’s nothing to this.”

    Drezner works with the National Center for Catastrophic Sport Injury Research, which aims to monitor all cases of sudden cardiac arrest and death among competitive athletes from middle school up through the professional level, and he said “I am not aware of any COVID-19 vaccine-related athletic death that’s occurred.”

    Eugene Chung, MD (University of Michigan, Ann Arbor), chair of the American College of Cardiology’s Sports and Exercise Cardiology Council, echoed that, saying, “The sports cardiology community is a pretty tight-knit community and we talk frequently and many of us have been involved with the cohort studies that have been published over the last year-and-a-half . . . and in those studies, there have been no cases that have been confirmed that have been due to the vaccine.”


    And so...


    It seems that neither COVID myocarditis, nor vaccine-induced myocarditis, is leading to a real (that is - not antivaxxer false info) spike in sudden deaths!


    The idea that athletes are keeling over after getting the shot was given new life late last month when similar claims were put forth by US Senator Ron Johnson, a Republican from Wisconsin, and former NBA great John Stockton, as reported by the New York Times. The Washington Post has delved into the timeline of how this rumored connection between the vaccines and athlete deaths spread, starting after 29-year-old Danish soccer player Christian Eriksen went into cardiac arrest during a Euro 2020 match in June 2021.



  • If a clown dies on stage its fake...


    Fact is death on play ground surged at least 10x after the "vaccine" campaign. But of course there is no relation as CDC did guarantee Pfizer....


    Of course many virus can cause mild heart inflammation but usually this is not myocarditis that destroys heart tissue.


    Many sponsored junior FM/R/JF/B mafia members "fake studies" have tried to invent myocarditis cases from regular heart inflammation.that usually do not result in systolic changes.

  • It sounds to me, like much of the US health system, broken.


    And we can all see from FM1's reaction that it is counterproductive, causing people who might otherwise look at the data mopre openly to take an anti-vaccination stand on the basis of obviously flawed interpretations from fringe antivaxxer websites such as TSN.

    It sounds to me ,it's you that's broken, continuing to push crap and putting people's lives at risk!

    Try reading more up to date concerns killer. Id like to see you label these doctors antivax!



    COVID Is Evolving Fast. Why Isn’t Our Response to It? Dr. Eric Topol on BA.5, next-gen vaccines, and America’s maddening capitulation to the virus.


    BA.5 Shows COVID Is Evolving Fast. Why Aren’t We Fighting Back?
    A long talk with Dr. Eric Topol about the BA.5 wave, next-gen vaccines, and why it’s long past time for the U.S. to get ahead of the coronavirus.
    nymag.com



    It’s not like all of a sudden there’s going to be a variant with total immune escape from vaccines. But in the CDC morbidity and mortality report, it said that two-dose vaccine effectiveness against hospitalization for the original BA.1 Omicron strain — we’re not talking about infections because we’re well past having good vaccine coverage for that — but for hospitalization, it dropped to 61 percent for two doses. And for BA.2 and BA.2.12.1, the latter of which is more like BA.5 but not as bad, two doses against hospitalization dropped to 24 percent. That should set off alarms because we don’t have a lot of people with a third shot. For three shots the efficacy jumped back up, but only to 52 to 69 percent with BA.2/2.12.1.


    Kaiser Southern California has also had two reports on vaccine effectiveness in their big network of patients, and they show the same attrition against hospitalizations as was seen in this much larger new comparison from the CDC.


    So how can you feel good about these data? I don’t see how. This narrowing benefit of the vaccines, which I think is due to more immune escape, not due to more infections in the unvaccinated, it’s still a very big gap. To drop down almost 40 points in effectiveness against hospitalizations with only two shots — this should be a signal that something is going on with our vaccine protection. But you don’t see anybody raising concerns about this. All you hear is happy talk that we have great protection from hospitalizations and deaths. I don’t know about that. These data don’t support that.


    So that suggests that hospitalizations will likely keep going up in the BA.5 wave?

    Yeah, they’re going to go up. The number of current U.S. hospitalizations is already over 40,000. I wouldn’t be surprised if it gets to 50,000 or 60,000. It isn’t going to get near 160,000, like it did with BA.1, only because so many people got infected with BA.1 and there’s some cross-immunity. But the number of hospitalizations has been going up substantially. It

  • now they are bribing kids to take jab and forging parents signature. This is criminal!!!


    LAUSD Vaccine Mandate Clashes with State Law: Mom Sues LAUSD for Illicitly Jabbing Her Son with Pfizer-BioNTech COVID-19 Vaccine


    LAUSD Vaccine Mandate Clashes with State Law: Mom Sues LAUSD for Illicitly Jabbing Her Son with Pfizer-BioNTech COVID-19 Vaccine
    Recently, a local CBS News affiliate in Los Angeles reported that Maribel Duarte, the mother of a 13-year-old boy named Moises, filed a lawsuit against the Los…
    www.trialsitenews.com


    Recently, a local CBS News affiliate in Los Angeles reported that Maribel Duarte, the mother of a 13-year-old boy named Moises, filed a lawsuit against the Los Angeles Unified School District (LAUSD). The plaintiff claims that Moises was illicitly vaccinated on the school premise. If the claims are true, 13-year-old Moises was offered a slice of pizza in exchange for receiving the Pfizer-BioNTech vaccine called BNT162b2. Additionally, the employee of the school district asked the 13-year-old to forge the name of his mother for the authorization of the COVID-19 vaccination. Moises went ahead and forged his mother’s signature. The claims: the plaintiff’s attorney argues that the LAUSD committed bribery, coercion, assault, battery, and medical negligence.


    School District Mandates

    Even though the vaccine formally approved by the U.S. Food and Drug Administration (FDA) is called Comirnaty, in the United States only the emergency use authorization (EUA) version of the product is in circulation, called BNT162b2. However, that legal approval triggered dozens if not hundreds of vaccine mandates across local government-based entities, such as school districts, across the United States. The LAUSD mandate was going to take effect this summer.


    As reported by NBC Los Angeles, the Los Angeles Unified School District issued a COVID-19 mandate last year. Earlier this month, a judge declared that the Los Angeles Board of Education’s authority is ‘great, but not unlimited,’ and that its COVID-19 vaccine mandate clashed with state law.


    Pizza for a Shot

    In the case of Moises, according to his mother in the purported recent lawsuit while Moises was attending the Barack Obama Global Preparation Academy, an employee there offered him a slice of pizza in exchange for the COVID-19 jab. The plaintiff claims that the employee even asked the boy to forge his mom’s signature while requesting that the boy keep the act a secret.


    If the claims are accurate, the vaccination was done without the consent of the boy’s parent—in this case his mother. Ms. Duarte is no anti-vaxxer as she opted to receive the COVID-19 vaccine, but she has concerns about her son’s health given his breathing problems and asthma present since he was a baby.


    Since receiving the vaccine the mother shared in a press release that her son is experiencing COVID-19 vaccine side effects. Since the jab, he hasn’t been able to do any physical fitness in the way he used to for example.


    Importantly, by August 13 LAUSD will drop the mandate as a condition of employment.


    LAUSD declared that it doesn’t comment on any litigation, whether ongoing or threatened and/or pending in status.

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