The Totally Civil Covid Thread. (Closing 31/05)

Japanese Researchers Correlate COVID-19 mRNA Antibody Count & Fever

Japanese Researchers Correlate COVID-19 mRNA Antibody Count & Fever

Researchers from Okayama University in Japan investigated the link between COVID-19 mRNA vaccines and side effects such as fever and fatigue, most often only…

www.trialsitenews.com

Researchers from Okayama University in Japan investigated the link between COVID-19 mRNA vaccines and side effects such as fever and fatigue, most often only lasting for an abbreviated period of time. The Japan-based research team enrolled 49 participants (university staff and students) who were not exposed to previous SARS-CoV-2 infection. Investigating the relationship between these side effects and the vaccine, the investigators found a relationship or an association between the incidence of fever and the number of antibodies in a particular person. This became more prominent after the third booster dose, as reported in the Journal of Epidemiology.

In this study, the participants were grouped into a “fever” and “non-fever” cohort in association with survey results. Interestingly the fever group was younger (20 to 49 years old) with a history of allergies. Studying the various levels of antibodies at varying times, the authors found the individuals in the fever group had markedly higher antibody counts than the other group.

Monitoring for any adverse reaction one week after the participants received the third dose of mRNA-1273 (Moderna), the study team measured antibody levels before and after the third dose was administered to the participants.

By employing various statistics, the study team probed for linkages associated with individuals’ fever and antibody levels at incremental times. The team factored in various variables such as differences in sex, age, preexisting allergy, and use of fever-reducing drugs associated with the participants.

What did they find?

By week number 1 post-vaccination, the investigators observed significantly greater antibody counts in the fever group as compared to the non-fever group. But by a month out, the correlation wanes between the frequency of fever and antibody count.

The first study highlighting associations between the triggering of a fever and antibody levels at various time points after the third dose of the mRNA-1273

Lead Research/Investigator

Naomi Matsumoto

Tomoka Kadowaki

Call to Action: Check out “Association Between Fever and Antibody Titer Trends After a Third Dose of the mRNA-1273 Vaccine.”

Association Between Fever and Antibody Titer Trends After a Third Dose of the mRNA-1273 Vaccine - PubMed

Association Between Fever and Antibody Titer Trends After a Third Dose of the mRNA-1273 Vaccine

pubmed.ncbi.nlm.nih.gov

last night Buffalo Bills defensive back collapsed on the field of cardiac arrest. His heartbeat restored on the field and in critical condition. Now the question, was he vaccinated?

Cardiac Tamponade After COVID-19 Vaccination

Potentially Fatal Complication Demands Assiduous Evaluation and Echocardiography

Cardiac Tamponade After COVID-19 Vaccination

Potentially Fatal Complication Demands Assiduous Evaluation and Echocardiography

petermcculloughmd.substack.com

By Peter A. McCullough, MD, MPH

I am concerned that bias amongst editors and publishers to reject manuscripts describing adverse outcomes with COVID-19 vaccination is resulting in relatively few papers that could be describing a large number of real patients with adverse outcomes. Dr. Hryniewicki et al, in 2021 described a potentially fatal case of pericarditis (fluid around the heart) which was so severe it was crushing the heart and could have caused death at home (pericardial tamponade).

Section of unvaxxinated Cov-19 patients:: https://www.nature.com/articles/s41586-022-05542-y

Main result from this very ill persons. The virus can randomly be found in all body parts at low concentration.

High numbers are found in the lung as most victims died from lung inflammation. Myocardium is only affect in patients with deadly numbers in lung. Same for some higher virus counts in brain tissue.

A very high virus count has been found in one thigh muscle... I guess also my vacuum cleaner is infected...

Brazil Study Reveals Efficacy of Infrared LED Treatment in Severe COVID-19

Brazil Study Reveals Efficacy of Infrared LED Treatment in Severe COVID-19

Recently, researchers associated with Anhembi Morumbi University (UAM) and their Institute of Biomedical Engineering, along with the University Center of…

www.trialsitenews.com

Recently, researchers associated with Anhembi Morumbi University (UAM) and their Institute of Biomedical Engineering, along with the University Center of Itajuba and the Center of Innovation, Technology, and Education, have the results from their study published in ScienceDirect. The study cohort was comprised of 30 patients undergoing COVID-19 treatment who were divided and allocated into two equal groups randomly: the LED group (LED), treated with infrared LED at 940 nm and conventional therapy, and the control group (CON), which received conventional treatment (antibiotic therapy for preventing superimposed bacterial infections, and physiotherapy) with LED irradiation off. Phototherapy used a vest with an array of 300 LEDs (940 nm) mounted on a 36 cm × 58 cm area and positioned in the patient's anterior thoracic and abdominal regions. The total power was 6 W, with 15 min irradiation time. Cardiopulmonary functions and blood count were monitored before and after treatment. The patients were treated daily for 7 days. Statistical analysis was conducted using a two-tailed unpaired Student's t-test at a significance level of α = 0.05. The findings were surprising.

Results

The LED group post-treatment showed a reduction in hospital discharge time and a statistically significant improvement for the following cardiopulmonary functions: Partial Oxygen Saturation, Tidal Volume, Maximum Inspiratory and Expiratory Pressures, Respiratory Frequency, Heart Rate, and Systolic Blood Pressure (p < 0.05).

Additionally, regarding blood count, it was observed that post-treatment, the LED group presented significant differences in the count of leukocytes, neutrophils, and lymphocytes.

In addition to the above results there were other significant clinical improvements in the intervention group. The hospital stay time for both groups, i.e., the time elapsed between patients' hospital intake and discharge, was measured (Mean ± SEM): LED (8 ± 0.2) days and CON (11.7 ± 1.4) days. That outcome reveals the effect of the photobiomodulation on reducing the time of hospital stay from 11.7 days to 8 days (p = 0.02).

Pulmonary auscultation, the time when adventitious noises (pulmonary snoring) improved from the date of patient hospital intake was measured for both groups, obtaining the results (Mean ± SEM): LED (3.5 ± 0.2) days, CON (5.6 ± 05) days, p = 0.0006, showing a statistically significant reduction on the time of pulmonary auscultation improvement in favor of the LED group.

Conclusion

Photobiomodulation therapy can be used as a complement to conventional treatment of COVID-19, promoting the improvement of cardiopulmonary functions, and minimization of respiratory symptoms.

The study design allowed blinding by both arms wearing the LED vest. The control group's vests did not emit infrared light. The LEDs emit light in the nonvisible infrared spectrum, so the intervention group did not know if their vests were actively emitting. The amount of infrared light emitted during this treatment is extremely low, and there were no AEs reported. While this trial was very small, with only 30 subjects, it still reached statistical significance in a myriad of clinically relevant endpoints. Being that the Sun emits many times more infrared power than the vests used, it begs the question of how effective Sun exposure could be for early treatment of acute Covid-19.

It's called vitamin D, they can't even say it!!!

Three years into the worst pandemic in a century, the CDC stands totally discredited as a public health agency. Throughout the COVID-19 pandemic, it has been increasingly politicized, tailoring science to match all the lies of both the Trump and Biden administrations, in order to suit the needs of Wall Street and corporate America.

The CDC cover-up of Omicron XBB.1.5 and the growing winter COVID surge

The CDC cover-up of Omicron XBB.1.5 and the growing winter COVID surge

There is no innocent explanation to the latest CDC cover-up, which was clearly deliberate and intended to prevent any public alarm that might disrupt the…

www.wsws.org

Benefits of Vaccinating Nursing Home Staff Diminished Amid Omicron Wave, Study Shows

Benefits of Vaccinating Nursing Home Staff Diminished Amid Omicron Wave, Study Shows

The benefits of having more nursing home staff take COVID-19 vaccines faded as the Omicron variant took hold, a new study of suggests.

www.theepochtimes.com

The benefits of having more nursing home staff take COVID-19 vaccines faded as the Omicron variant took hold, a new study of some 15,000 facilities across the United States suggests.

The authors of the study, a team of researchers from the University of Chicago, sought to find out whether higher levels of staff vaccination rates were actually associated with lower adverse outcomes of COVID-19 in nursing homes. As of Dec. 19, 2022, two weeks before their paper was published online in JAMA Network Open, nursing home staff and residents accounted for nearly 2.9 million COVID-19 infections and 165,000 deaths.

“When vaccines became available in December 2020, staff and residents in nursing homes were among the first to be deemed eligible for vaccination,” the researchers wrote, noting that staff vaccination rates varied substantially by facility before the Biden administration rolled out a vaccination mandate for all health care workers in November 2021.

Upon analyzing data reported to the federal health authorities by 15,042 nursing homes between May 30 to Dec. 5, 2021—an eight-month period before the Omicron wave hit, the team said higher rates of staff vaccinations did appear to have at least some protective benefits.

Specifically, the team said that increasing weekly staff vaccination rates by as little as 10 percentage points during that period was associated with 0.13 fewer weekly COVID-19 cases per 1,000 residents, 0.02 fewer weekly COVID-19 deaths per 1,000 residents, and 0.03 fewer weekly COVID-19 staff cases.

However, during the Omicron wave from Dec. 5, 2021, to Jan. 30, 2022, increasing staff vaccination rates in these same facilities appeared to no longer produce the same benefits.

Circulating Spike Protein Detected in Post–COVID-19 mRNA Vaccine Myocarditis

https://www.ahajournals.org/doi/10.1161/CIRCULATIONAHA.122.061025?cookieSet=1

Abstract

BACKGROUND:

Cases of adolescents and young adults developing myocarditis after vaccination with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)–targeted mRNA vaccines have been reported globally, but the underlying immunoprofiles of these individuals have not been described in detail.

METHODS:

From January 2021 through February 2022, we prospectively collected blood from 16 patients who were hospitalized at Massachusetts General for Children or Boston Children’s Hospital for myocarditis, presenting with chest pain with elevated cardiac troponin T after SARS-CoV-2 vaccination. We performed extensive antibody profiling, including tests for SARS-CoV-2–specific humoral responses and assessment for autoantibodies or antibodies against the human-relevant virome, SARS-CoV-2–specific T-cell analysis, and cytokine and SARS-CoV-2 antigen profiling. Results were compared with those from 45 healthy, asymptomatic, age-matched vaccinated control subjects.

RESULTS:

Extensive antibody profiling and T-cell responses in the individuals who developed postvaccine myocarditis were essentially indistinguishable from those of vaccinated control subjects, despite a modest increase in cytokine production. A notable finding was that markedly elevated levels of full-length spike protein (33.9±22.4 pg/mL), unbound by antibodies, were detected in the plasma of individuals with postvaccine myocarditis, whereas no free spike was detected in asymptomatic vaccinated control subjects (unpaired t test; P<0.0001).

CONCLUSIONS:

Immunoprofiling of vaccinated adolescents and young adults revealed that the mRNA vaccine–induced immune responses did not differ between individuals who developed myocarditis and individuals who did not. However, free spike antigen was detected in the blood of adolescents and young adults who developed post-mRNA vaccine myocarditis, advancing insight into its potential underlying cause

Quote from Fm1

Specifically, the team said that increasing weekly staff vaccination rates by as little as 10 percentage points during that period was associated with 0.13 fewer weekly COVID-19 cases per 1,000 residents,

The original cause for 0.13 fewer cases was the happiness of the old seeing the young doing more bad than them...

Only fools - or professional cheaters use such figures in any report....

In Germany 1/3 of the vaxxed health care personal - includes care homes - did suffer from vaxx illness and was off for > 3 days...

Spike Protein in the Blood Associated with Myocarditis—Is Lack of Aspiration the Culprit?

Spike Protein in the Blood Associated with Myocarditis—Is Lack of Aspiration the Culprit?

Could more study outcomes imply even more evidence that the lack of aspiration leading to intravascular administration of the COVID-19 vaccines represents the…

www.trialsitenews.com

Could more study outcomes imply even more evidence that the lack of aspiration leading to intravascular administration of the COVID-19 vaccines represents the root cause behind the myopericarditis serious adverse events? In past TrialSite articles, this topic was raised as a serious consideration. See “Covid-19 Injection protocols may be leaving patient at risk” and “Germany changes national guidelines for Covid-19 vaccines—embraces aspiration.” What is the culprit here? Improper aspiration? What else could trigger circulating spike proteins in the blood?

Now a new study delivers additional information that the immunological responses in the symptomatic patients vs. the controls were the same. The exception was that the patients with serious adverse events were found to have circulating full-length spike proteins in their blood. The only explanation for this is an intravascular injection unless science can explain another reason why the spike protein moves around the plasma.

This most recent prospective study from January 2021, through February 2022, involved the collected blood of 16 patients who were hospitalized at Massachusetts General for Children or Boston Children’s Hospital for myocarditis, presenting with chest pain with elevated cardiac troponin T after SARS-CoV-2 vaccination. The study team undertook extensive antibody profiling, including tests for SARS-CoV-2–specific humoral responses and assessment for autoantibodies or antibodies against the human-relevant virome, SARS-CoV-2–specific T-cell analysis, and cytokine and SARS-CoV-2 antigen profiling. They compared the results with those from 45 healthy, asymptomatic, age-matched vaccinated control subjects.

The large team of scientists wrote:

“Extensive antibody profiling and T-cell responses in the individuals who developed postvaccine myocarditis were essentially indistinguishable from those of vaccinated control subjects, despite a modest increase in cytokine production. A notable finding was that markedly elevated levels of full-length spike protein (33.9±22.4 pg/mL), unbound by antibodies, were detected in the plasma of individuals with postvaccine myocarditis, whereas no free spike was detected in asymptomatic vaccinated control subjects (unpaired t-test; P<0.0001).”

TrialSite contributor Paul Elkins who monitored this study also was able to find a couple of additional papers published earlier this year with support for aspiration to reduce the serious adverse events, including one in Springer and a preprint uploaded to ResearchGate.

Lead Research/Investigators

Lael M. Yonker, Massachusetts General Hospital, Mucosal Immunology, and Biology Research Center, Division of Infectious Disease

Zoe Swank, Harvard Medical School, Wyss Institute for Biologically Inspired Engineering Brigham and Women’s Hospital,

Yannic C. Bartsch, Harvard Medical School, Ragon Institute of MGH, MIT, and Harvard

Alessio Fasano, Massachusetts General Hospital, Mucosal Immunology, and Biology Research Center, Division of Infectious Disease

David R. Walt, Harvard Medical School, Wyss Institute for Biologically Inspired Engineering Brigham and Women’s Hospital,

To aspirate or not to aspirate? Considerations for the COVID-19 vaccines - Pharmacological Reports

Syringe aspiration when vaccinating intramuscularly was not recommended before the pandemic due to the lack of conclusive evidence that it provides any…

link.springer.com

https://www.researchgate.net/publication/360236565_Aspiration_During_Vaccination_Evidence_for_SARS-CoV-2_Vaccination

The Swiss Covid dashboard :: https://www.covid19.admin.ch/d…accineBreakthroughRel=abs

clearly shows that vaxxines do not work for age > 65. Two things you should count in. Most people age > 65 had an infection already and then got just 1 vaxx shot. So the number of vaxxinated only is low (in UK it was < 50%). The hospitalization rate thus is still 2x higher than for unvaxx.

As China shows today:: CoV-19 is an illness of the old that just stay at the cliff and need a last soft push.

Here the infections (tested ones) did go back by more than 50% and thus do not believe CDC and the fear monger that the new Omicron version does any harm. The fact is US case/death numbers decline!

Excess mortality at new heights in Switzerland : https://dam-api.bfs.admin.ch/h…s-e-14.03.04.05-wr/master

Most places have 30% record is 70% one place with 10%. Cov-19 deaths are just a tiny fraction of it.

Randomized Clinical Trial: Ivermectin Reduces 72% COVID-19 Infection in Study Population

Randomized Clinical Trial: Ivermectin Reduces 72% COVID-19 Infection in Study Population

MedinCell announces positive results for the SAIVE clinical study in the prevention of Covid-19 infection in a contact-based population. The study conducted in…

www.trialsitenews.com

MedinCell announces positive results for the SAIVE clinical study in the prevention of Covid-19 infection in a contact-based population. The study conducted in 399 participants met its primary efficacy endpoint with a reduction of 72% of COVID-19 infection in the group treated with daily oral administration of ivermectin compared to the placebo group.

Ivermectin administered for 28 days demonstrated acceptable safety and tolerability without any unexpected safety signals.

The SAIVE study was conducted to support mdc-TTG program, whose objective is to provide prevention of Covid-19 infection for weeks or months with a single injection of a long-acting formulation of ivermectin based on MedinCell’s proprietary technology, BEPO.®

MedinCell is a pharmaceutical technology company that develops a portfolio of long-acting injectable products in various therapeutic areas by combining its proprietary BEPO® technology with active ingredients already known and marketed. U.S. FDA approval for the first product using BEPO® technology for patients with schizophrenia is expected in H1 2023. Two other products are in clinical Phase 3. In addition, several programs should reach the clinic in 2023 and 2024, including two Global Health initiatives in woman's health (contraception) and malaria, supported by the Bill & Melinda Gates Foundation and Unitaid respectively. Through the controlled and extended release of the active pharmaceutical ingredient, MedinCell makes medical treatments more efficient, particularly thanks to improved compliance and to a reduction in the quantity of medication required. The BEPO® technology makes it possible to control and guarantee the regular delivery of a drug at the optimal therapeutic dose for several days, weeks or months, depending on the product, starting from the subcutaneous or local injection of a simple deposit of a few millimeters, fully bioresorbable. BEPO® biocompatible polymers, the key components of each MedinCell formulation, are produced and scaled-up at GMP quality level, and already producible at commercial stage through MedinCell’s joint-venture with Corbion (Euronext - CRBN). MedinCell collaborates with tier one pharmaceuticals companies and foundations to improve Global Health through innovative therapeutic options. Based in Montpellier, MedinCell is a public company (Euronext, MEDCL), currently employing 150 people from over 30 different nationalities. http://www.medincell.com

I hope the liers and deniers are paying attention, they are getting older

Vitamin D is the key to a long healthy life!

Alzheimer’s Disease Researchers Study Gene Associated With the Brain’s Immune Cells

Alzheimer’s Disease Researchers Study Gene Associated With the Brain’s Immune Cells - Neuroscience News

Reduction of the INPP5D gene variant found in the brain's microglia could help to diminish the risk of late-onset Alzheimer's disease.

neurosciencenews.com

Summary: Reduction of the INPP5D gene variant found in the brain’s microglia could help to diminish the risk of late-onset Alzheimer’s disease.

Source: Indiana University

Indiana University School of Medicine researchers are studying how the reduction of a gene variant found in the brain’s immune cells could diminish the risk of late-onset Alzheimer’s disease.

The research team, led by Adrian Oblak, Ph.D., assistant professor of radiology and imaging sciences, and Peter Bor-Chian Lin, a Ph.D. candidate in the Medical Neuroscience Graduate Program at Stark Neurosciences Research Institute, recently published their findings in Alzheimer’s & Dementia.

Immunomodulatory Effects of Vitamin D Supplementation in a Deficient Population

Immunomodulatory Effects of Vitamin D Supplementation in a Deficient Population

In addition to its canonical functions, vitamin D has been proposed to be an important mediator of the immune system. Despite ample sunshine, vitamin D…

www.ncbi.nlm.nih.gov

INPP5D

INPP5D protein expression summary - The Human Protein Atlas

DARPA Memo: United States Created SARS-CoV-2?

DARPA Memo: United States Created SARS-CoV-2?

Back in January 2022, the far-right activist-journalist group Project Veritas reported&nbsp;on the fact that in March 2018 DARPA rejected a request for funding…

www.trialsitenews.com

Back in January 2022, the far-right activist-journalist group Project Veritas reported on the fact that in March 2018 DARPA rejected a request for funding from EcoHealth Alliance “over safety concerns and the notion that it violates the basic gain of function research moratorium.” According to documents obtained by Veritas, the National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institute of Health (NIH) under the direction of Dr. Anthony Fauci went ahead and funded the research in both Wuhan at the Wuhan Institute of Virology and at U.S. locations. Veritas reported that “Dr. Fauci has repeatedly maintained, under oath, that the NIH and NIAID have not been involved in gain of function research with the EcoHealth Alliance program. But according to the documents obtained by Project Veritas which outline why EcoHealth Alliance’s proposal was rejected, DARPA certainly classified the research as gain of function.”

Small News Site Breaks Big Story?

Next, on January 27 2022 the Fallbrook and Bonsall Village News reported on an August 13, 2021 DARPA memorandum which stated that, "SARS-COV2 is an American-created recombinant bat vaccine, or its precursor virus," (emphasis added) DARPA wrote. "It was created by an EcoHealth Alliance program at the Wuhan Institute of Virology (WIV), as suggested by the reporting surrounding the lab leak hypothesis. The details of this program have been concealed since the pandemic began. These details can be found in the EcoHealth Alliance proposal response to the DARPA PREEMPT program Broad Agency Announcement (BAA)HR00118S0017, dated March 2018, a document not yet publicly disclosed----SARS-CoV-2's form as it emerged is likely as a precursor, deliberately virulent, humanized recombinant SARSr-CoV that was to be reverse-engineered into a live attenuated SARSr-CoV bat vaccine."

DARPA Fails to Deny Authenticity

These materials were sent to TrialSite months ago, and frankly were treated with true skepticism. Recently TrialSite received yet more information on this topic and finally sought out to better understand the validity and veracity of these artifacts especially to the existence of the DARPA memorandum from August 13, 2021.

We note that it is written to the Inspector General of the Department of Defense from US Marine Corps Major Joseph Murphy, Commandant of the Marine Corps Fellows, DARPA. But was the document authentic? Could it have been a forgery?

The subject is, “SARS-CoV-2 ORIGINS INVESTIGATION WITH US GOVERNMENT PROGRAMS UNDISCLOSED DOCUMENT ANALYSIS.”

In an attempt to verify this document, TrialSite communicated with DARPA. In the email this media explains that we sought to determine the validity and veracity of the document in circulation from Project Veritas on DARPA formal letterhead purportedly discussing the origins of SARS-CoV-2 as the U.S. government.

DARPA did respond. Tabatha Thompson, Chief of Communications for DARPA, wrote back that:

“The agency is precluded by Federal Acquisition Regulations from discussing who may or may not have bid on a DARPA program, and we are unable to confirm the authenticity of the documents Project Veritas has published.

The agency has never funded EcoHealth Alliance directly, nor indirectly as a subcontractor.”

Interestingly, Ms. Thompson never denied that the memorandum was authentic. We at TrialSite are grateful for the agency’s response.

As time marches on, many aspects of the COVID-19 pandemic and related vaccines raise lots of questions. Some outstanding ones are 1) where did SARS-CoV-2 originate, and 2) on another front, why is significant evidence of problems with our mRNA vaccines being downplayed in the media? 3) If this memo is accurate, does it reflect DARPA’s attempt to pinpoint culpability of SARS-CoV-2 origins with the NIH and EcoHealth Alliance? Or, on the other hand, 4) if the DARPA memo is a forgery (and again DARPA would not confirm or deny authenticity), who would want to create such controversy, conflict and the conditions for division within and among American society?

If this memo is accurate, it’s just truly disturbing and the American people will need to align for a change, and demand answers. We have left a message to Project Veritas for their point of view and have not heard back as of yet.

The RBS (restless brain - mobile, gamepad, playstation,TV) Syndrome leads to a higher CVD (cardio vascular disease) rate:: https://jamanetwork.com/journa…89-46dc-9a07-3bd112c24386

An other factor promoted by lockdowns, school lockouts etc...

UK ambitious plan for mRNA cancer vaccine with German company BioNTech.

BBC link.

"Unlike chemotherapy, which attacks lots of different cells as well as the cancer, the mRNA treatment is tailor-made for the individual and presents the immune system with bits of genetic code from the specific cancer so it can attack only the tumour.

This makes it more expensive to produce. BioNTech says it will be affordable for healthcare systems. But much more work is needed to determine whether the cost can be justified for the NHS. Being commercially sensitive, the details of the partnership between the Government and BioNTech have not been disclosed."

Quote from ZenoOfElea

UK ambitious plan for mRNA cancer vaccine with German company BioNTech.

Nothing new... Already sold by Roche that programs T-Cells.. Horrific prize...

From New York time today for brainless US readers.

You immediately see that almost all Covid cases are from tested hospitalized people. This also explains that almost all US claimed CoV-19 deaths have an other cause...

UK Excess death soar too. But there are always weeks that are higher. Switzerland had a continuous increase too. For age >64 its 30%.

UK excess deaths increase

Excess deaths, (2016 to 2019, and 2021)In November 202247,611 deaths registered in England4,083 deaths (9.4%) above the November five-year averageCoronavirus...

youtu.be

The data :: https://www.ons.gov.uk/peoplep…/weekending23december2022