The Totally Civil Covid Thread. (Closing 31/05)

UK excess mortality is back again at 20%:: https://www.ons.gov.uk/peoplep…nal/weekending31march2023

off topic but this is NOW the world we live in

New UN-backed legal recommendations normalize sex with minors, outraged critics say

'Children may consent to sex with adults. This has been the plan all along,' social media influencer charges

New UN-backed legal recommendations normalize sex with minors, outraged critics say | Fox News

A shocking report issued by international legal experts with the backing of the United Nations appears to open the floodgates to normalize sex with minors.

"Sexual conduct involving persons below the domestically prescribed minimum age of consent to sex may be consensual in fact, if not in law," the Geneva-based International Commission of Jurists wrote in March with an assist from UNAIDS and the Office of the United Nations High Commissioner for Human Rights.

The report is titled "The 8 March Principles for a Human Rights-Based Approach to Criminal Law Proscribing Conduct Associated with Sex, Reproduction, Drug Use, HIV, Homelessness and Poverty.

Repulsive, but that sounds more like a political/social issue...which we like to stay away from here.

Quote from Shane D.

Repulsive, but that sounds more like a political/social issue...which we like to stay away from here.

My apologies, it made my blood boil

i posted this study a year ago now we can see why CBD is effective in stopping SARS COV2. CBD acts as an inducer of cyp2 enzymes upregulating vitamin D expression thru out the body.

Vitamin D is the key!

Cannabidiol inhibits SARS-CoV-2 replication through induction of the host ER stress and innate immune responses

https://www.science.org/doi/10.1126/sciadv.abi6110

Abstract

The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and ongoing coronavirus disease 2019 (COVID-19) pandemic underscores the need for new treatments. Here, we report that cannabidiol (CBD) inhibits infection of SARS-CoV-2 in cells and mice. CBD and its metabolite 7-OH-CBD, but not THC or other congeneric cannabinoids tested, potently block SARS-CoV-2 replication in lung epithelial cells. CBD acts after viral entry, inhibiting viral gene expression and reversing many effects of SARS-CoV-2 on host gene transcription. CBD inhibits SARS-CoV-2 replication in part by up-regulating the host IRE1α ribonuclease endoplasmic reticulum (ER) stress response and interferon signaling pathways. In matched groups of human patients from the National COVID Cohort Collaborative, CBD (100 mg/ml oral solution per medical records) had a significant negative association with positive SARS-CoV-2 tests. This study highlights CBD as a potential preventative agent for early-stage SARS-CoV-2 infection and merits future clinical trials. We caution against current use of non-medical formulations as a preventative or treatment therapy.

Effects of Cannabidiol Interactions with CYP2R1, CYP27B1, CYP24A1, and Vitamin D3 Receptors on Spatial Memory, Pain, Inflammation, and Aging in Vitamin D3 Deficiency Diet-Induced Rats

Effects of Cannabidiol Interactions with CYP2R1, CYP27B1, CYP24A1, and Vitamin D3 Receptors on Spatial Memory, Pain, Inflammation, and Aging in Vitamin D3 Deficiency Diet-Induced Rats - PubMed

<span><b>Introduction:</b> The study was planned to investigate memory-enhancing, anti-inflammatory, and antiaging potential of cannabidiol (CBD) on vitamin…

pubmed.ncbi.nlm.nih.gov

Abstract

Introduction: The study was planned to investigate memory-enhancing, anti-inflammatory, and antiaging potential of cannabidiol (CBD) on vitamin D3 deficient diet (VDD)-induced rats. Materials and Methods: Cytochrome P-450 enzymes were analyzed by RT-PCR method and others biomarkers by enzyme-linked immunosorbent assay. Results: CYP2R1 and CYP27B1-mRNA were significantly increased by 39.29 and 38.37%, respectively, while; CYP24A1-mRNA was significantly reduced by 21.39% compared to VDD. Vitamin D3 receptor protein expression was significantly increased by 148.3%, 60.48%, and 142.03% in liver, kidney, and brain, respectively, compared to VDD group. Vitamin D3 metabolites and serotonin were significantly increased more than 60% and 100%, respectively, compared to VDD. Spatial memory (in terms of total distance, escape latency) and pain score were improved compared to VDD. Cytokines were significantly reduced than VDD. Besides, levels of superoxide dismutase (49.61%), glutathione peroxidase (178.87%), acetylcholine (25.40%), and klotho (145.57%) were significantly increased than VDD. Conclusions: Study findings supported that CBD interacts with CYP2R1, CYP27B1, CYP24A1, and vitamin D receptors, resulting in increased vitamin D3 metabolites, which improved memory, pain tolerance, reduced inflammation, and aging through modulating antioxidative enzymes, cytokines, and neurotransmitters in VDD-induced rats.

Hello to all readers and posters of this thread. After some deliberation, the LENR-Forum staff has decided to phase out this thread, effective the last day of May 2023, after which it will be closed for new comments.

The Covid Pandemic Crisis is virtually over in all the world, and we live in a post pandemic order with many changes and challenges, and we by all means encourage you to continue to discuss these important issues on other places more proper to that end. LENR-Forum is happy to enhance the focus in LENR and directly related topics.

In the event of a new Pandemic, we are keen to open the thread again, by popular request, let's hope is not the case anytime soon.

Circulating Spike Protein Detected in Post-COVID-19 mRNA Vaccine Myocarditis

Circulating Spike Protein Detected in Post-COVID-19 mRNA Vaccine Myocarditis - PubMed

Immunoprofiling of vaccinated adolescents and young adults revealed that the mRNA vaccine-induced immune responses did not differ between individuals who…

pubmed.ncbi.nlm.nih.gov

Quote from Curbina

we live in a post pandemic order with many changes

Quote from Fm1

Circulating Spike Protein Detected in Post-COVID-19 mRNA Vaccine Myocarditis

"Order" without rationality...

all hail Pfizer and the coming new NORMAL era

where the NORMAL human condition is to have circulating Spike Protein...

Spikecine for neonates... infants adults ...maybe we can have it in the water supply

Spikecine forever..

TM 11.48

so they're saying that the spike protein evades recognition because there's

plenty of Spike protein antibody made and it's made in NORMAL amounts and it

works physiologically NORMALLY

so that they're saying here that the spike protein persists because the

antibody response is NORMAL and NORMAL

amounts of Spike protein antibody are produced which works PERFECTLY well

so the reason the spike protein persists is because everything's working PERFECTLY

it makes no sense at all no sense at all

now is this incompetence from these writers

well these are leading academics and doctors specialists in um in in the Boston area

so no I don't think they're incompetent at all in any way shape or form

um why didn't the peer reviewers pick this up?

one comment on the YT video from Alison...

"I was myself a research scientist in Boston a couple of decades ago, at DFCI, right next door Harvard Medical School.

My boss was a professor at Harvard Medical School. She would never have submitted papers containing such obvious omissions! We would have probably been sent home

These papers coming out regarding vaccines are so obviously restricted in what they can portray.

The frustration this brings about is enormous because the general public make their health decisions on flaky, inaccurate, nonsensical summaries from such papers with the help of MSM that just go according to a dictated narrative. Often very uncomfortable to listen to, as these things highlight how badly we've been coerced into making bad choices for ourselves and our kids, but thank you so much for bringing us these daily videos.

They shine a very important light on what has become very shady/dark areas of science indeed.

Alison

Long Covid.(+ vaccine injury)./Omicron. treatment

around the. 2. min mark..

omicron is becoming more flulike

.. head. cold. sinus congestion. like. natural corona viruses

definitely that's. what I've had for the last. 2 wks.

courtesy of one of my wife's patients

both of us. had. 4.'vaccines.' but she had. 4. spikecines. "awesome.-not"

both have the same +ve. test and symptoms

No fever... slight cough..post. nasal drip. type? but lingering. sinus. inflammation/congestion ..fatigue

I 'll try. Virgin coconut Oil. (contains monolaurin...only. 10aud/1000 ml

hopefully it gets the Creactive protein down

Well it looks like being fat isn't so healthy ! Someone needs to tell woke America!!!!!!!!!!!

A Significant Correlation Between Obesity and COVID-19 Associated Deaths Seen Across 142 Countries

A Significant Correlation Between Obesity and COVID-19 Associated Deaths Seen Across 142 Countries

An empirical analysis looked at plausible associations between COVID-19 mortality and the proportion of obese adults across 142 countries around the globe.…

www.trialsitenews.com

An empirical analysis looked at plausible associations between COVID-19 mortality and the proportion of obese adults across 142 countries around the globe. Researchers observed a statistically significant positive association between the two, which held true regardless of income, age or sex. The association was strongest for the sub-sample of high-income countries. The study findings were published in Scientific Reports.

Limited amounts of empirical data have assessed the link between obesity and COVID-19 mortality across countries. Obesity rates are greater in relatively high-income nations, whereas low-income nations tend to have more significant proportions of lean individuals. Correspondingly, the mortality rates of severe SARS-CoV-2 infections are usually higher in the more prosperous nations.

For the present study, researchers explored the effect of obesity on country-level variations in mortality rates of SARS-CoV-2 infections.

Data on COVID-19-associated mortality were provided by the European Centers for Disease Control and Prevention (ECDC). Comparatively, data on obese adult proportions were retrieved from the Global Health Observatory (GHO) database of the World Health Organization (WHO). Individuals with body mass index (BMI) values exceeding 30.0 kg/m2 were considered obese, whereas those with BMI values between 25.0 kg/m2 and 29.9 kg/m2 were considered overweight.

Data on population-level parameters, including age and sex, were retrieved from population estimates published by the United Nations Population Division. Data on nation-level income, which were categorized as low, lower-middle, upper-middle, and high, were determined by per capita Gross National Income (GNI) estimates of 2019 that were determined using the World Bank’s Atlas classification technique.

The analysis showed a statistically significant positive association between COVID-19 mortality and the proportion of obese in adult populations spanning 142 countries. This association holds across countries belonging to different income groups and is not affected by a population’s median age, proportion of the elderly, and/or proportion of females. The estimated elasticity of COVID-19 mortality, looking at the proportion of obese adults, is the highest for the sub-sample of countries that belong to the high-income group. While limits of confidence intervals around the point estimates of these elasticities range between 0.7 and 2.1, on an average, every percentage point increment in the proportion of obese adults contributes to an additional 1.5% points to COVID-19 mortality for high income countries.

The positive association between COVID-19-associated mortality and obesity found in the analysis indicates that effective weight management strategies and programs could aid in improving COVID-19 severity outcomes and reducing the health burden of the disease, the authors conclude.

Quote from RobertBryant

Long Covid.(+ vaccine injury)./Omicron. treatment

around the. 2. min mark..

omicron is becoming more flulike

.. head. cold. sinus congestion. like. natural corona viruses

definitely that's. what I've had for the last. 2 wks.

courtesy of one of my wife's patients

both of us. had. 4.'vaccines.' but she had. 4. spikecines. "awesome.-not"

both have the same +ve. test and symptoms

No fever... slight cough..post. nasal drip. type? but lingering. sinus. inflammation/congestion ..fatigue

I 'll try. Virgin coconut Oil. (contains monolaurin...only. 10aud/1000 ml

hopefully it gets the Creactive protein down

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My wife and I went thru this recently, it was definitely more flu like than our previous omicrom infection. We used cold ezze to relieve the sinus and a shot of B12 from our primary care for the fatigue and supplements of niacin and thiamine. No extended symptoms

Quote from RobertBryant

both of us. had. 4.'vaccines.' but she had. 4. spikecines. "awesome.-not"

What was your third choice? Novavax?

Any spike vaxxine will make you problems RNA vaxxines of course a live long, where long depends on your luck.

RNA therapy make you at least 10x more vulnerable for Omicron according UK data. If we look at actual Kerala data then its 40x! But there classic vaxxines have been used - at least officially...

Quote from Fm1

The positive association between COVID-19-associated mortality and obesity found in the analysis indicates that effective weight management strategies and programs could aid in improving COVID-19 severity outcomes and reducing the health burden of the disease, the authors conclude.

The paper:: https://www.nature.com/articles/s41598-023-33093-3

Quote from Wyttenbach

What was your third choice? Novavax?

Twice, Novavax,,,,Its main worth was not its efficacy but its spikelessness

Each time I was interrogated by a doctor

according to the aussie Ministry of truth.." why don;t you take RNA.."?

each time I asked why the spikecine was "preferred'

each time I got the parrot answer

"

"mRNA vaccines (Pfizer or Moderna) are preferred as COVID-19 booster doses. Although not preferred, Novavax can be used as a booster dose for:

• people who have a contraindication to mRNA vaccines (including those who have had a serious adverse event following mRNA vaccines, such as a history of anaphylaxis or myocarditis attributed to an mRNA vaccine)
• people who do not prefer an mRNA vaccine"

Ivermectin Delivers Statistically Significant Results Against COVID-19 (Including Omicron) in SAIVE Trial

Ivermectin Delivers Statistically Significant Results Against COVID-19 (Including Omicron) in SAIVE Trial

Recently, the French biotech venture MedinCell presented its ivermectin-based summary at the European Congress of Clinical Microbiology &amp; Infectious…

www.trialsitenews.com

Recently, the French biotech venture MedinCell presented its ivermectin-based summary at the European Congress of Clinical Microbiology & Infectious Diseases in Copenhagen, Denmark. The poster is included at the bottom of this article. Called the SAIVE Trial (NCT05305560), this randomized, double-blind, multicenter, parallel-group, placebo-controlled clinical trial assessing the efficacy and safety of ivermectin in a post-exposure population involved the following of study participants for 56 days. RT-PCR tests were performed on days 1, 4, 7, 10 and 28 or when infection was suspected. Conducted at 11 clinical trial sites in Bulgaria between March and Oct. 2022, the study sponsor sought to evaluate the efficacy of a continuous administration of oral ivermectin as post-exposure prophylaxis against SARS-CoV-2 infection in confirmed contact cases. Also, the study authors published in the poster that the SAIVE trial would further reinforce the safety of continuous exposure to ivermectin, as evaluated in a previous phase 1 study (NCT04632706). Notably, out of 400 enrolled, 399 participants were randomized in a 1/1 ratio to ivermectin (200 mg on day 1, then 100mg/day up to day 28) or matching placebo. The sponsor reports that the inclusion criteria were confirmed contact within 5 days with a positive COVID-19 case (assessed by RT-PCR). Targeting a primary endpoint of the proportion of confirmed infections between groups from baseline to day 28, the study investigators also assessed during the study time to positivity, severity of symptoms after confirmed infection, and efficacy as a function of variant type. The SAIVE trial was led by Principal Investigator Anna Kostova at Medical Center Medic, Ltd, MedinCell reports in the results with summaries included below. The outlook for ivermectin becomes brighter with these findings.

Poster-SAIVE-April2023-OK2.pdf

The French biotech reports a statistically significant difference associated between active and control groups in terms of risk of infection with SARS-CoV-2 between D1 and D28 post-treatment initiation. Relative Risk Reduction (RRR) was highly statistically significant with a 71.57% difference with respectively 30/200 positive cases in the ivermectin group and 105/199 in the placebo group (mFAS population (399 patients)) with p<0.0001. Of course, some critics suggest Absolute Risk Reduction should also be included in such metrics.

Positive

Positive

Negative

Negative

Total

Total

Treatment

N

%

N

%

N

%

Ivermectin

30

15

170

85

200

100

Placebo

105

52.8

94

47.2

199

100

Statistics

N

Value

95%CI

Odds Ratio (OR)

399

0.158

0.098-0.255

Relative Risk (RR)

399

0.284

0.199-0.405

Relative Risk Reduction (RRR)

399

0.715

0.594-0.801

All of the above were deemed statistically significant.

This study revealed a statistically significant difference between the two groups in terms of WHO Covid-19 scale6 for disease progression. This indicates milder symptoms in the ivermectin group compared to placebo, in case of infection.

Variant ID

Ivermectin

Placebo

Total

BA.1.1

10

44

54

BA.5

20

60

80

Variant ID not recorded

0

1

1

Total

30

105

135

Furthermore, the company reports Omicron BA.1.1 and BA.5 variants were present during the study, and ivermectin demonstrated an equivalent high efficacy whatever the variant with a significant difference (p value<0.0001).

High Viral Load

Variant ID

Ivermectin

Placebo

BA.1.1

0

40

BA.5

4

59

Total

4

99

Low Viral Load

Variant ID

Ivermectin

Placebo

BA.1.1

10

4

BA.5

16

1

Total

26

5

The study team also reported a significant delay in regard to Time to Positivity between the groups, and most infections occurred between D7 (3 cases in the ivermectin group vs. 38 in the placebo group) and D10 (25 cases vs. 57 respectively) (Hazard Ratio of 0.213 (p-value < 0.0001)).

What about safety?

As reported in the study poster, no deaths or serious adverse events (SAE) were reported. Of 173 reported Adverse Events (AEs), most were mild, and 135 were related to COVID-19. All participants with documented infection received standard care (steroids, anticoagulants – mostly aspirin- vitamins C and D) and were followed until resolution. No participant had severe symptoms, required oxygen, or was hospitalized. There was an excellent tolerance to ivermectin. It’s, of course, known as a very safe drug, approved and used for various parasite-borne diseases in the tropics.

Conclusion

MedinCell reported in this conference that the SAIVE trial demonstrated highly statistically significant evidence in a large, randomized, double-blind, placebo-controlled study that daily oral treatment with ivermectin reduced the risk of infection following exposure to SARS-CoV-2. Ivermectin was also shown to be safe in doses and duration higher than currently used in approved indications

https://www.businesswire.com/news/home/20230417005617/en/MedinCell-SAIVE-Study-Data-to-Be-Presented-at-ECCMID-2023

Perh

Quote from Fm1

that daily oral treatment with ivermectin reduced the risk of infection following exposure to SARS-CoV-2. Ivermectin was also shown to be safe in doses and duration higher than currently used in approved indications

Perhaps Uttar Pradesh suffers from less misinformation than the FDA

"

• Currently available data do not show ivermectin is effective against COVID-19. Clinical trials assessing ivermectin tablets for the prevention or treatment of COVID-19 in people are ongoing.
• Taking large doses of ivermectin is dangerous."

        The growing spread of rumors, misinformation and disinformation about science, medicine, and the FDA, is putting patients and consumers at risk. We’re here to provide the facts.

Quote from RobertBryant

Taking large doses of ivermectin is dangerous."

from Dr Jackie Stone Zimbabwe

See table below - Delta Nov 2021:
Ivermectin triple therapy (ITP): 1. Fully implemented/mandated - 0.05 to 0.2/mil died
2. Available: 0.94 - 2.1/mil died
3. Prohibited: 12 -100/mil died US =>50 TIMES THE DEATH RATE IN AFRICA
2000 TIMES THE DEATH RATE OF UTTAR PRADESH
Oops.

Looking back, who here was right about Sweden, and who wrong?

The New York Times’ Stunning Confession on Sweden’s Pandemic Response - Foundation for Economic Education (fee.org)

Quote

After some deliberation, the LENR-Forum staff has decided to phase out this thread, effective the last day of May 2023, after which it will be closed for new comments.

I pretty much disagree with this decision - the smell of Big Pharma interests is behind persistent attacks of this sunken thread. In particular the input of FM1 is very helpful.

Quote

Are you interested in new visitors to this forum actually seeing a place where LENR is seriously, rationally, and knowledgeably discussed?

Yes exactly - this thread may lure interest of many visitors about the rest of this forum.