@Jed
Anesthesia may not be fully understood although more and more about it is being learned. But it is very extremely unlike LENR. The effect can be produced at will with extreme, completely reproducible reliability with only a few, very unusual exceptions. If that were not true, modern surgery would be entirely impossible. There could not be anything less like LENR than anesthesia.
The problem with LENR isn't a lack of understanding or theory. As Cam noted, you need to have something to need a theory for other than scattered claimed results in obscure journals, most of which date from around 1990. Rossi, Defkalion, and perhaps Miley, Nanospire and Brillouin were that hope with claims of high power reproducible LENR. And where are most of those now?