First injection of mRNA (agains cancer) nearly 20 years ago (in the author's body), published in 2007
Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent - PubMed
The development of new treatments in the post-genomic era requires methods for safe delivery of foreign genetic information in vivo. As a transient, natural…
pubmed.ncbi.nlm.nih.gov
and in cancer patient for an anticancer vaccine, published in 2008
Results of the first phase I/II clinical vaccination trial with direct injection of mRNA - PubMed
Vaccination against tumor antigens has been shown to be a safe and efficacious prophylactic and therapeutic antitumor treatment in many animal models. Clinical…
t.co