Covid-19 News

Quote from Wyttenbach

Did you see the Pfizer RNA gen therapy induced CoV-19 cases among younger 10..29 in Israel. Factors more vaccinated young in hospital compared to unvaccinated...

If you consider your own argument - that children with known risk factors are much more likely to suffer form COVID than others - this is explained. You can see that for 12-15 age range - with a very small number of children - vaccinated and unvaccinated are about level per 100K. That is much worse than for higher ages.

• Anyone with an at-risk child would get them vaccinated
• Most of the hospitalisation would be driven by at-risk children
• Therefore more vaccinated in hospital.

This is a general confounder that tends to make vaccination hospitalisation or death rates look worse than they really are. Any known risk factors are positively correlated with vaccination - so unless you can control for them they represent powerful confounders. But it will particularly affect young ages where COVID risks are much lower and children with strong co-morbidities - e,g, immunocompromised will be in regular contact with hospitals, and will be very strongly advised to get vaccinated.

You know that of course - therefore I'd appreciate it if you indicated to others who maybe are not as used to thinking about this typemof maths as you are that this is an issue.

THH

Quote from Shane D.

Yes, of course if they test positive they have COVID. Most kids who test for COVID though are asymptomatic. Many, if not most, of the kids in the hospital are there because they are sick from RSV, then test positive for COVID. So were you a reporter, how would you describe this? Another example of how bad the COVID epidemic is, or something altogether different? Most from what I read, are reporting it as proof COVID has finally hit children hard, where before they were spared.

The author did say these children may be getting COVID from the hospital. That does not make sense to me. I do not agree with all he says. He could have left that out, and done himself a favor. As it is, he distracted from his good investigative reporting.

I would like to know, as does he, if this is another "fear porn" news cycle. Are all these kids being hospitalized because of RSV, or COVID? It is very plausible this is nothing more than a bad RSV season, as UK children have not been impacted by the Delta variant like US children...yet.

Also, it is a fact hospitals get paid much more for a COVID patient, than one with RSV. So there is a financial incentive for them to go along with this COVID narrative, as it was to go along with the PCR cycle threshold controversy last year. Like the old saying goes "follow the money".

• We don't have these problems much in the UK thank God.
• We track who catches COVID in hospital - and now it is low even with delta 9it was high first wave when people did not understand what needed to be done).
• We don't have cash incentives to make one diagnosis or another.

Fear porn is a very strong phrase. The key issue about COVID deaths has always been the hospitals. Once enough people get ill that they are stretched, and non-COVID patients don't get properly treated, doctors complain and no-one can ignore it. Nothing to do with fear porn.

In the first wave there was a problem of COVID being underdiagnosed because it looked like RSV and COVID testing was limited. Someone who tested positive for RSV would not be tested for COVID.

This might be the opposite effect, a positive test for COVID might mean test for RSV was not done. I'd hope not.

We could work out whether this has a significant effect on the figures - I don't like your It is very plausible this is nothing more than a bad RSV season without proper evidence, by looking at the age distribution. RSV will peak below age 10 and have almost nothing above 10. COVID will be higher 17-10 then lower < 10.

Unfortunately there is a big caveat here. Under 12 children can't get vaccinated, even if at risk. Over-12 can get vaccinated. So we expect a COVID jump up below twelve.

We have to compare rates 10-11 (predominately COVID) wit rates 2-9 (predominately RSV).

Let us say whether we can get that from the US:

OK - I've looked a bit - i can't find that data - though it is probably there somewhere maybe only at state-level.

I'm not sure who you think is distorting this? reporters tend not to do proper science. I've heard this suggestion, and scientists have said, well, it is possible, but also it could be related to differing infection rates etc. I'm inclined to be more generous to the US health system than you are. I believe most hospitals would be testing for RSV and COVID. But, if a child tests for both, and falls ill, why are you assuming that illness is mainly caused by RSV? RSV is very infrequently a problem in older ages because by then everyone has immunity and infections are mild. So how would you want hospitals to record these figures?

Note how RSV hospitalisation decreases even over 1st 12 months of life:

THH

OK here is a solution to Shane's question. Age range shows COVID not RSV is responsible for the uptick in illness. Not very scientific though. And uptick in illness may be because of increasing infection rates, not that delta is more deadly. Nevertheless, if you see this as a problem it is a COVID problem, not RSV.

"The majority of the patients who have been admitted, are between 10 and 13 years of age, which puts them right at or just below the age of vaccination," said Hysmith. "This is why it is critically important for adults and children to get vaccinated as soon as possible."

For those who are still hesitant about getting the vaccine, Godiwala pleaded for them "to stop thinking about yourself and think about others," such as medically fragile children, the immunocompromised and the population under 12 not yet eligible for a vaccine.

Front-line workers warn of significant increase in pediatric COVID patients

Since the onset of the pandemic, nearly 4.3 million children have tested positive for COVID-19.

abcnews.go.com

Study Led by Fred Hutch & Emory Investigators Shows SARS-CoV-2 Infected Patients Have Broad, Effective & Possibly Long-Term Immunity

Study Led by Fred Hutch & Emory Investigators Shows SARS-CoV-2 Infected Patients Have Broad, Effective & Possibly Long-Term Immunity

A sophisticated team of researchers operating at Fred Hutchinson Cancer Research Center and Emory University suggest that transcending the COVID-19

trialsitenews.com

A sophisticated team of researchers operating at Fred Hutchinson Cancer Research Center and Emory University suggest that transcending the COVID-19 pandemic necessitates what they refer to as “long-lived immunity to SARS-CoV-2.” Leading a longitudinal study involving 254 COVID-19 patients over an eight-month period, the study team observed what they referred to as “durable broad-based immune responses” in those mild-to-moderate COVID-19 patients. The investigators remind all that this class of infection represents the vast majority of cases. Although still not peer-reviewed—hence the findings are by no means verified—they do articulate that the prospects look promising as a confluence of factors indicates those infected with SARS-CoV-2 indicate “broad and effective immunity” that could “persist long-term in recovered COVID-19 patients.” The findings, of course, must be reviewed and confirmed, and the authors’ views don’t necessarily reflect those of the academic medical centers that employ them. TrialSite suggests if these findings hold up, they represent powerfully positive information for further study. The study authors will continue tracking the population for two years.

The Study

The study population included 55% female and 45% male, all between 18-82 years old, with a median age of 48.5. Based on the World Health Organization (WHO) index of disease severity, 71% of these study participants were recorded as “mild disease” while 24% had “moderate disease,” with 5% classified into the “severe disease” category.

In this longitudinal study targeting SARS-CoV-2 specific B and T cell memory after infection, the team recruited 254 COVID-19 confirmed patients via two sites in both Seattle and Atlanta commencing April 2020 through a 250 day period involving follow up visits for patient monitoring. The team collected blood samples 2 to 3 times from 165 patients and 4 to 7 times from 80 patients, enabling a longitudinal analysis of SARS-CoV-2 specific B and T cell responses covering a larger number of infected patients.

The Findings

The findings are quite promising in that the novel coronavirus (SARS-CoV-2) spike binding and neutralizing antibodies exhibit what they refer to as a “bi-phasic decay with an extended half-life of >200 days. The authors asserted that this means the COVID-19 patients are generating “longer-lived plasma cells.” But there’s more. The group, working out of prestigious labs in Seattle and Atlanta, discovered that within the SARS-CoV-2 infected patients were observable boosts to “antibody titers” to the pathogen in addition to “common beta coronaviruses.”

Moreover, and quite promising, they documented “spike-specific IgG+ memory B cells persists,” which means that this contributes to “a rapid antibody response upon virus re-exposure or vaccination.” Meaning that whether an individual was infected by SARS-CoV-2 or vaccinated, the immunity response looks robust.

In addition, the Fred Hutch and Emory-led team explained that “virus-specific CD4+ and CD8+ T cells are polyfunctional and maintained with an estimated half-life of 200 days.” They found it curious that the study patient “CD4+ T cell responses equally target the nucleoprotein,” which indicates to the investigators “the importance of including the nucleoprotein in future vaccines.”

The authors concluded that the study’s results indicate “broad and effective immunity may persist long-term in recovered COVID-19 patients.”

Limitations

Importantly, this study doesn’t include Delta variants of interest samples which could have different results. The study only covers patients up to 8 months, and this necessitates models to estimate immune response half-lives thereafter. The investigators continue the study for two years so they can corroborate their models with subsequent experimental data on the persistence of immune memory.

Notably, most of the subjects had mild COVID-19. The team didn’t have sufficient data for any compelling breakthrough involving what they refer to as “extreme presentations,” that is, either asymptomatic cases or severe COVID-19.

But TrialSite adds that over 90% of COVID-19 cases fall in the mild-to-moderate category.

Funding

Several funders contributed to this important study, including the National Institute of Allergy and Infectious Diseases and the Office of the Director of the National Institutes of Health via grant awards, as Oliver S. and Jennie R. Donaldson Charitable Trust (R. Ahmed); Paul G. Allen Family Foundation Award #12931 (MJM); Seattle COVID-19 Cohort Study (Fred Hutchinson Cancer Research Center, MJM); the Joel D. Meyers Endowed Chair (MJM); An Emory EVPHA Synergy Fund award (MSS and JW); COVID-Catalyst-I3 Funds from the Woodruff Health Sciences Center (MSS); the Center for Childhood Infections and Vaccines (MSS and JW); Children’s Healthcare of Atlanta (MSS and JW), a Woodruff Health Sciences Center 2020 COVID-19 CURE Award (MSS) and the Vital Projects/Proteus funds.

Lead Research/Investigator

Juliana M. McElrath, MD, PhD, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center

Kristen W. Cohen, PhD, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center

Susanne L. Linderman, PhD, Emory Vaccine Center, Emory University, Department of Microbiology and Immunology

For the rest of the authors, check out the link to the preprint uploaded to medRxiv.

Call to Action: Follow the link to read this important study.

Quote from THHuxleynew

You can see that for 12-15 age range - with a very small number of children - vaccinated and unvaccinated are about level per 100K.

Not exactly. The vaccinated group is much smaller but with about 4x cases... This will only be seen about 4-6 weeks after vaccination then the picture will change. This statistic is one more prove that Pfizer is crap and should not be used during a peeking pandemic!

Quote from Fm1

Study Led by Fred Hutch & Emory Investigators Shows SARS-CoV-2 Infected Patients Have Broad, Effective & Possibly Long-Term Immunity

The paper (22MB long download) https://www.medrxiv.org/conten…04.19.21255739v1.full.pdf

Quote from Fm1

The investigators remind all that this class of infection represents the vast majority of cases.

Just to remind everyone that a good 40% of COVID infections are asymptomatic, and not cases.

There is also evidence (sorry no link) that the level of immune response from natural infection scales with the severity of the infection. TANSTAAFL.

Not clear is how natural immunity and vaccination scale over time. Vaccination induces a stronger response - but of course natural immunity to delta is more accurate than vaccination for original, targetting delta.

Quote from Shane D.

Most kids who test for COVID though are asymptomatic. Many, if not most, of the kids in the hospital are there because they are sick from RSV, then test positive for COVID.

If so, they must be infected in the hospital. (They are nosocomial, or HAI.) Has the author confirmed this? Is there data showing that many patients are infected by COVID in hospitals, and many pediatric patients are? I wouldn't know, but if that is what the author is saying, he should cite data to back it up.

Quote from Shane D.

The author did say these children may be getting COVID from the hospital. That does not make sense to me. I do not agree with all he says. He could have left that out, and done himself a favor. As it is, he distracted from his good investigative reporting.

It does not make sense to you?? What else could it mean? How can you not agree? If people do not have COVID when they go into the hospital with RSV, and then later during their stay they develop COVID, they must have been infected by someone or some surface in the hospital. It has to be nosocomial, by definition.

Quote from Shane D.

Also, it is a fact hospitals get paid much more for a COVID patient, than one with RSV.

Where did you read that? In Atlanta, the hospitals say they are paid less for COVID patients than for other diseases. They are losing money. They are anxious to get back to other more profitable procedures.

Are you sure pediatric RSV in particular pays less? If so, perhaps that is because it is a mild disease that does not call for as many expensive drugs or full time nursing. The only time I was in the hospital, with pneumonia, they gave me mostly over-the-counter drugs (at an inflated price) and looked in several times a day, but they did not have to do much. It could not have cost them much. A person can drop dead from pneumonia in an hour, so the hospital is the place to be, but a mild case does not require intensive care.

Quote from THHuxleynew

OK - I agree we can stop spread with good case tracking - but that is only possible with lowish infection rates.

Case tracking would be great, but as you say the numbers may be too high. Fortunately, rapid do-it-yourself tests are now widely available, so people can find out they have COVID and self-quarantine. They can also do some personal case tracking. They can inform their friends and keep an eye on their own family.

In other words, to some extent, do-it-yourself tests can substitute for case tracking.

The pharmacist told me these do-it-yourself tests are easier to administer than the 2020 tests. Less painful. They cost $23 to $35. The tests at clinics are still free as far as I know, so they might be better for poor people.

Regarding W's assertion that he both has and has not been vaccinated:

Quote from THHuxleynew

Somone else can reconcile these two statements, I hope?

Quantum superposition.

Quote from THHuxleynew

Somone else can reconcile these two statements, I hope?

W responds to a claim that he is anti-vax, by saying he is fully vaxxed, that is, he has received during his life the typical vaccine regime offered in Switzerland. Yet just because he has not received a Covid-19 vaccine, and is outspoken against the Pfizer vaccine, people call him anti-vax, and can't reconcile what he has said. Pathetic!

Speaking of which, those health bureaucrats lauded by THH and Jed and Zeus for mask mandates and lockdowns, I hope they get to digest the preprint out of Brown University on Rhode Island. Researchers report a 21 point drop in IQ in roughly 100 children less than 5 years of age since Covid started, compared to the decade previous.

https://www.medrxiv.org/content/10.1101/2021.08.10.21261846v1.full.pdf

Haseltine recommends a mutlimodal approach to Covid

including not only vaccines but antiviral drugs..

:While this is a valuable contribution, we urgently need to supercharge the development of antiviral drugs with the same priority we did for vaccine"

Ivermectin is he invisible unmentionable

It never happened.. at least not in the mainline Western media...

Israel’s Recent Surge Confirms We Need A Multimodal Strategy To Fight Covid-19

Cases are occurring in both vaccinated and unvaccinated populations, yet with one of the highest vaccination rates in the world, Israel’s experience confirms…

www.forbes.com

Quote from Mark U

Researchers report a 21 point drop in IQ in roughly 100 children less than 5 years of age since Covid started

Mark U - unlike 99% of the popele - it seems - following this: I don't see it as political. Therefore:

• Vaccines
• Facemasks
• Lockdown
• Drug development

are all judged on merits.

You know well that IQ for children less than 5 does not correlate with attainment later on and corresponds to a few months difference in time at which they develop speech etc - and that will be affected by lockdown. Picking up such things in that way is a political point-scoring argument - although the effect of lockdowns overall on children from socially deprived families in particular is a major tragedy, and must be balanced against the tragedy of health systems overwhelmed and people dying.

In the UK Labour and the independent enquiry looking at what needs to be done to help children recover from this said it needed £15 billion over 3 years - money well spent if a generation are not going to be badly effected. the government a much more limited plan - £1.5 billion.

Anyway:

• Vaccines. COVID vaccines have more risks than normal ones, but personally much smaller risks and uncertainty than COVID. Since it is one or the other (breakthrough infections are 10X less likely to be nasty) it is a no-brainer. the mRNA vaccines are thus far the best of the bunch and I have heard no rational arguments against them - and lots of anti-vax propaganda.
• mRNA vaccines. People like W are always scared of new technology that can have risk. I don't see the risks as more than for any other new vaccine. The scare stories about gene therapy (sic) are silly. If little bits of foreign RNA and DNA were so serious we would all be incapacitated by Common Colds which deliver continuously mutated RNA or DNA the whole time. not to mention COVID itself of course!
• Facemasks. Since these cost essentially nothing, and in many settings our best guess is that they provide some real protection, it seems really stupid not to use them. All the other options - crashing the health system, leaving everyone with COVID to die at home when it is known less people will die in ICU at hospital, lockdowns, crashing the economy because everyone is afraid to go out, are so much worse that providing they make some reduction in R0 - even 5% - they are worth it. Mandates are needed if you want people to comply, juts as they were with seat belts. People follow others. For me the personal liberty arguments here are frivolous, and this is similar to requiring people to drive cars that have passed their MOT.
• Lockdowns. I've always seen this as a political question not a scientific one. We know what happens if you let infection rates climb. You have a choice. Many people dying and hospitals overflowing, or some form of lockdown. Personally I have a lot of sympathy with the Swedish - keep society open and lock down 50% of the population (those more vulnerable). I would add compulsory face masks (of a best-for-purpose-but-still-practical) type in all enclosed public spaces. This is likely to help, whether by slowing exponential increases, smoothing out hospital demand, or by reducing overall disease burden by providing on average lower initial doses (variolation https://www.nejm.org/doi/full/10.1056/nejmp2026913). But free democratic governments will find any strategy that crashes the health system impossible. Look at Italy first wave.
• Drug development. Like everyone else I am impatient with the glacial speed of testing and regulation - and did not appreciate the need for it until i looked carefully at the arguments on both sides. Cocktails of hope it will work drugs help no-one and likely harm. The doctors have a choice in how much they rush out for mass use drugs that have little evidence. This is a big topic, my point is that in the case of HCQ and ivermectin I think they have got it right. There is great hope for the future from immunomodulatory drugs, and also for nasal delivery. E.g. EXO-CD24. There is hope for antivirals but this has always been a much more difficult task.

I think the people (it seems mostly but not all also anti-vax) who quite understandably see the harm of lockdowns, don't see the political impossibility for a western democracy letting older people die like flies due to lack of hospital space. Remember, in hospital the death rate will be half.

I think Western countries were not in a position to eliminate COVID when it first started, as China did. Had they taken extreme action to do so we would be much better off. We were not helped by lack of timely info from China - even when it was quite clear what COVID was no-one considered eradication as a possibility because of the great political difficulty. It was possible then as China showed, it is not now. Ok - maybe the price of freedom is forever being more vulnerable to nasty pandemics.

I think everyone is underestimating the harm to people and society of long-term side effects of COVID and its continued variants. The only tool we have thus far to help with this is vaccines - which will need continued redevelopment.

I think many people are not considering that without vaccines we have less tools to deal with COVID variants which could be much scarier than current.

I think many people are not putting this pandemic into its scientific context where our understanding of molecular biology. Genetics and epigenetics, and the immune system is on a cusp. In 10 years time we will be so muhc better equipped to deal with a pandemic. 10 years previously we would have been so much less well prepared.

I would like to know why, for so many people, all these different issues conflate so that those who are anti-lockdown are also more than normally suspicious of vaccines, against use of face masks, over-optimistic about drugs and in favour of scientifically unevidenced drug cocktails.

On the other side I don't see those who are in favour of lockdowns being anti-drug-development. they are just less likely to think they know better than the scientists who decide what to test, and what to add into standard treatment. There is a fascinating debate about how much regulators should shut eyes and hope, allowing random drugs based on PR and popular fashion. In the case of HCQ this would (slightly) have killed more people. In the case of ivermectin we do not know - the possibility of slight help or slight harm is both there. I don't myself have much problem allowing idiots to dose themselves with whatever they want. I can see it as overall being bad for us. Those dosed and overconfident will like W exhibit risky behaviour. The risks are not just personal ones.

THH

Quote from RobertBryant

It never happened.. at least not in the mainline Western media..

No, but the media does not accurately reflect the views of scientists, nor what is actually done. I see no lack of application to developing and trialing drugs. Quite the reverse. I wonder why people are so concerned about israel? They have a very low death rate. As in the UK with high vaccination rates the infection rate does not seem to go much beyond 1 in 50, and health systems can cope with that without lockdown.

Variants are scary but will be this whatever action we take - unless we can eradicate COVID - which now is impossible given animal reservoirs and dysfunctional infected states.

Quote from Mark U

those health bureaucrats lauded by THH and Jed and Zeus for mask mandates and lockdowns

And that is the problem.

Both mandates, and lockdowns, are political decisions trading one harm for another, informed (one would hope) by science. Casting this in terms of beaurocracy shows a bias that has nothing to do with the major harms on both sides of these questions, and everything to do with a political ideology that from my POV makes it more difficult to get wise decisions.

Nor am I (not sure about Zeus) lauding these things without specific context. I guess I tend to be in favour of mask mandates because the harm of such is very small - at least in most countries where they are not political) and the possible benefit in reducing peak hospital demand or long-term disability in population is so much higher. I really can't understand the people must be free arguments against.

FLCCC Weekly Update: Delta Variant Up to 1000X the Viral Load, Protocols Updated as Risks Grow Across the Board

FLCCC Weekly Update: Delta Variant Up to 1000X the Viral Load, Protocols Updated as Risks Grow Across the Board

The Front Line COVID-19 Critical Care Alliance (FLCCC) recently held its weekly update with the organization's founders, including Dr. Pierre Kory and Dr.

trialsitenews.com

The Front Line COVID-19 Critical Care Alliance (FLCCC) recently held its weekly update with the organization’s founders, including Dr. Pierre Kory and Dr. Paul Marik to discuss both the delta variant and protocol changes. The recent update took on the growing crisis associated with the delta variant and the latest pandemic surge. Trouble spreads across the country with this delta variant-driven wave as record numbers of children now get sick and even land in the hospital. The FLCCC ivermectin-based protocol has been updated due to the powerful viral charge associated with the delta variant. According to the FLCCC, one Chinese study discovered viral charges nearly one thousand times as the last variant. Dr. Kory and Dr. Marik express concerns about the growing threat that the delta variant represents. While they are still generally upbeat about ivermectin and their core protocol, they acknowledge that the pandemic’s stakes are shifting as variants become far more transmissible and include higher viral loads. TrialSite reports worldwide breakthrough cases, that is, vaccinated people that succumb to delta variant-based infection. Most recently, in Israel, a doctor at Herzog Hospital reported a majority of the hospitalized patients with the delta variant were fully inoculated. Other troubling news came from a recent Mayo Clinic-based study, yet to be peer-reviewed. It revealed how the Pfizer-BioNTech vaccine plummeted in effectiveness to 42% in July, while Moderna declined but not nearly as much. The COVID-19 pandemic isn’t anywhere near over, and with the imminent school year, concerns grow that children will bring the pathogen back home. TrialSite has direct evidence of this occurring in Utah as the summer schools, at least some of them, generated new youth infections. In the meantime, TrialSite reported that even China, which has spent 1.5 years constantly monitoring, controlling, and cordoning off its population, not to mention quarantining in a “zero-tolerance” COVID policy, saw nearly a thousand cases of delta surface in hours. TrialSite shared a point of view recently that few in the West probably understand: China’s municipalities are feeling the financial pressure as they bear the weight of constant zero-tolerance, not the top Communist Party. China’s economy could be more fragile than most know. Onward to the delta surge summary and the FLCCC concerns.

TrialSite’s Brief Update on Surge

In the U.S., the pandemic has come in surges or waves, starting with the first one during the outbreak from April 2020 through the summer months of 2020. Then a much bigger wave occurred beginning October 2020 through February 2021. At the height of this intense surge, 259,616 new cases occurred per day on a 7-day average by January 8th, 2021. At that point, vaccinations were just starting, so those inoculation benefits really didn’t start manifesting for at least a couple of months. By the end of May 2021 and into June, the total number of new cases, based on a 7-day average, was down to 11,882 daily new cases by June 27th. However, the delta variant was surging by then, and by July 4th, with major Holiday parties in places like beach communities in Florida to patio BBQs in Texas, many were concerned that the pathogen would spread. And that’s exactly what happened. The number of cases started heading north again by July 2021, and by August 13th, the daily case count was 186,840, a high growth rate.

TrialSite has reported that the total number of deaths was far worse early on, but that’s also due to several factors, such as:

The virus was brand new.

There were no known treatments or vaccines.

Mortality issues in long-term care facilities took a huge toll, for example.

By the second big wave, more knowledge was available about COVID-19, and consequently, the overall mortality rate waned. There are still far fewer total deaths by this third wave, but concerns are mounting and daily deaths are headed north. Moreover, more young people are sick and getting hospitalized with the delta variant than before. Moderna’s KidCOVE trial is filling up as parents are again concerned and want protection for their kids, reported TrialSite.

By August 1st, the 7-day daily number of deaths per day was 362, and by August 13th, that same number was at 651.

As the FLCCC confirms in their video, the number of young people infected spikes as Reuters reports a record number of young people are now hospitalized due to COVID-19 at 1,902 hospitalizations.

The CDC data shares that Blacks and Latinos have a higher probability of both hospitalization and death. But other data indicates the disparity the socioeconomic and racial or ethnic disparities could be considerably higher. TrialSite reported, based on Los Angeles County data, how high-risk, elderly blacks could be nearly six times more at risk for death than whites.

FLCCC Must Update its Ivermectin Protocol

The delta variant represents some problems, but according to Dr. Kory, “nothing that cannot be solved.” Highly transmissible, the viral load is much higher. One Chinese study reveals that delta has up to a thousand times higher the viral loads than previous variants. Exposure to the first symptom presentation is much faster now, reports the FLCCC doctors. Moreover, the time from first symptom presentation to hospitalization accelerates.

Patients are showing up in the hospital, and it’s harder to get ahead with the existing FLCCC protocol. The more one waits, the harder it is to keep on top of it. Delta is so strong that TrialSite has reported on numerous scenarios worldwide demonstrating the growth of breakthrough infections. But it’s not just the vaccines that are succumbing to infection. So are the traditional ivermectin-based protocols, reports Dr. Kory. Hence the FLCCC doctors now update the protocol to accommodate the delta variant’s powerful viral load. Kory notes that despite over 300 million total vaccination doses in America, the pathogen spreads seamlessly. Clearly, with so many breakthrough cases around the world, this crisis isn’t about a “pandemic of the unvaccinated” but rather as TrialSite considers, “a pandemic for us all.”

“This variant is quite a vicious thing, “reports Dr. Marik. Younger patients are showing up sicker and facing profound inflammatory responses that can ensue. They are not responding as well to the standard FLCCC treatment protocol. Marik declares at the very time of symptom presentation, treatment must commence. There is no time to waste, reports Marik.

Given this variant, not to mention Lambda—which could represent a forthcoming problem—Kory recommends a dose twice per week to keep tissue and blood concentrations high enough to protect against the new variant. This is based on FLCCC’s empirical data along with their own risk assessment at this time.

Call to Action: Follow the link to the FLCCC’s weekly update to learn more about the delta variant, how the FLCCC’s ivermectin-based protocol has been updated, and other COVID-19 updates here.

Quote from Fm1

FLCCC Must Update its Ivermectin Protocol

The delta variant represents some problems, but according to Dr. Kory, “nothing that cannot be solved.” Highly transmissible, the viral load is much higher. One Chinese study reveals that delta has up to a thousand times higher the viral loads than previous variants. Exposure to the first symptom presentation is much faster now, reports the FLCCC doctors. Moreover, the time from first symptom presentation to hospitalization accelerates.

Patients are showing up in the hospital, and it’s harder to get ahead with the existing FLCCC protocol. The more one waits, the harder it is to keep on top of it. Delta is so strong that TrialSite has reported on numerous scenarios worldwide demonstrating the growth of breakthrough infections. But it’s not just the vaccines that are succumbing to infection. So are the traditional ivermectin-based protocols, reports Dr. Kory. Hence the FLCCC doctors now update the protocol to accommodate the delta variant’s powerful viral load. Kory notes that despite over 300 million total vaccination doses in America, the pathogen spreads seamlessly. Clearly, with so many breakthrough cases around the world, this crisis isn’t about a “pandemic of the unvaccinated” but rather as TrialSite considers, “a pandemic for us all.”

The traditional ivermectin protocols were succumbing to infection before if we are to believe RCTs.

But this looks to me like a PR change where now ineffectiveness of ivermectin as treatment will be attributed to lack of using ivermectin as prophylaxis?

A pandemic for all of us surely underestimates the utility of a one-off treatment (vaccine) that reduces death and hospitalisation and long-term nasties by a factor of 10? Of course, COVID can affect anyone - even W.

Canada Learned from the Chinese Experience—Now Bets National Pandemic Response on Moderna, the New Pharma Power Elite

Canada Learned from the Chinese Experience—Now Bets National Pandemic Response on Moderna, the New Pharma Power Elite

The COVID-19 pandemic has been a boon for Moderna. Reuters recently followed up on TrialSite’s assessment that the Cambridge, MA-based venture

trialsitenews.com

Canada Learned from the Chinese Experience---Now Bets National Pandemic Response on Moderna, the New Pharma Power Elite

The COVID-19 pandemic has been a boon for Moderna. Reuters recently followed up on TrialSite’s assessment that the Cambridge, MA-based venture has converted crisis to opportunity, driving billions in sales and a $155+ billion market cap (compared to $25b last June). Meanwhile, Moderna is still securing subsidies from taxpayers, as we reported recently with the kidCOVE study (they had taxpayers pay them $144 million). The company, which trades under the NASDAQ symbol MRNA, just inked a memorandum of understanding (MOU) with the government of Canada to build a state-of-the-art messenger mRNA manufacturing facility in that country. This is to build the foundation to support the nation with direct access to rapid pandemic response capabilities as well as to offer access to their portfolio of respiratory-based viruses in development. Of course, Canada learned the hard way from this pandemic. Few in America know, because it wasn’t broadly covered, that this nation first selected for its national strategy during the start of the pandemic the vaccine from CanSino Biologics in China. That led to a debacle as China customs never let the investigational product ship to Canada due to what is most certainly a political crisis surrounding Canada, America, and China. TrialSite reported that news, while most other outlets either didn’t even know what was happening or were intimated to publish. Moderna epitomizes the new crisis-driven, publicly supported nature of capital accumulation moving forward.

The MoU was announced today by the Hon. François-Philippe Champagne, Minister of Innovation, Science and Industry of Canada, and Stéphane Bancel, Moderna’s Chief Executive Officer in Montreal, Canada.

Canada’s Pandemic Hard Sino-Knocks

Search TrialSite for news about CanSino Biologics and Canada for information about what went so terribly wrong. The founders of CanSino Biologics actually came up with the idea for the venture while residing in Canada, as there were natural ties between the venture and the nation. For whatever reason, Canada opted not to participate in Operation Warp Speed (or perhaps Trump didn’t invite them). Hence the Anglo-North American nation ventured to China for its vaccine strategy. China’s brand is heavily tarnished for how its government intervened and disrupted the supply of the product.

What has the Pandemic Done for Modena—or Put another Way, What has Moderna Done for the Pandemic?

How does a company accumulate a fortune in a crisis? Moderna was a money loser—although with lots of promise and plenty of investment. But what do their finances look like now, just 1.5 years into the pandemic? From de minimis revenue to over $7 billion with nearly $4 billion profits—one could say that in a truly civilized society, to profit at this level while capitalizing on taxpayer subsidies via the National Institutes of Health (NIH) and others during a pandemic could be considered shocking and obscene. Not! Here they are celebrated. Remember their market cap in June 2020 was $25.25 billion; that number today—$155.54 billion! With the recent study out of Mayo Clinic that Pfizer’s vaccine’s effectiveness waned to 40%, Moderna’s was still hovering above 70% with the delta variant. Of course, these study results must be further verified via peer review processes. The pandemic is fundamentally reshaping the society, economy, and culture in ways still unfolding, but one thing is for sure: the winner-take-all economy intensifies.Thus far, investors in Moderna are winners. Who are the top five institutional holders?

· Baillie Gifford and Company

· Flagship Pioneering Inc.

· Blackrock Inc.

· The Vanguard Group

· Morgan Stanley

About Moderna

In the ten years since its inception, Moderna has transformed from a science research-stage company advancing programs in the field of messenger RNA (mRNA) to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across six modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for both clinical and commercial production at scale and at an unprecedented speed. Moderna maintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna’s capabilities have come together to allow the authorized use of one of the earliest and most effective vaccines against the COVID-19 pandemic.

Moderna’s mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing. It has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases, and auto-immune diseases. Today, 23 development programs are underway across these therapeutic areas, with 15 programs having entered the clinic. Moderna has been named a top biopharmaceutical employer by Science for the past six years.

Quote from Wyttenbach

Not exactly. The vaccinated group is much smaller but with about 4x cases... This will only be seen about 4-6 weeks after vaccination then the picture will change. This statistic is one more prove that Pfizer is crap and should not be used during a peeking pandemic!

The paper (22MB long download) https://www.medrxiv.org/conten…04.19.21255739v1.full.pdf

That is not true.

קורונה - לוח בקרה

For 12-15 age rage 37% are double vax, and 63% are single vax or novax (the single dose vax group is quite small so does not much change figures).

Then, using absolute number of active patients (APs):

unvaccinated + partly vaccinated APs: 3197

vaccinated APs: 159

159/0.37 = 430

3197/0.63 = 5074

Thus the chance of becoming an active patient is 12X less for vaccinated than unvaccinated children age 12-15.

Your statement above is wrong by a factor of 40X

I hope (for the sake of anyone here with children in the age group) you correct your statement above.

Even so, for this age range, risks are much lower than at higher ages. For this range we have no serious illness and no deaths (probably because those most at risk, known to hospitals, are 100% vaccinated).Data on children with long COVID is still just not reliable, but this remains clearly a real risk:

Long COVID afflicts kids too. Here's what we know so far.

Many children can also experience lingering symptoms after getting COVID-19. But scientists are struggling for answers, so parents are banding together to…

www.nationalgeographic.co.uk

Australian researchers tracked 171 younger COVID-positive children (median age 3) and found that 8 percent reported post-COVID manifestations up to two months later. In this study, though, by six months all of them had recovered.

In early June, Dutch researchers conducted a survey of paediatricians in their country who said 89 youths in their care were affected. Most troubling, says study coauthor Caroline Brackel, a paediatric pulmonologist at Amsterdam University Medical Centres, was that in more than a third of these children, symptoms were serious enough to cause “severe restrictions in daily life, mostly due to excessive tiredness, problems concentrating, and difficulties breathing.”

In the U.K., recognising this burgeoning problem, the NHS just announced that it will spend £100 million to create treatment centres around the country and to educate paediatricians about long COVID care.

In the UK, a dataset released by the Office for National Statistics on July 1 stated that the prevalence of self-reported ongoing symptoms following coronavirus (COVID-19) infection in the UK was 962 for the four weeks up to 6 June – of which 13 were aged 2-11, and a further 20 aged 12-16 – meaning a total of 3.5% of current long COVID cases reported were in children younger than 16.

So far, no studies have documented the rate in the U.S., something Alicia Johnston, a paediatric infectious disease clinician at Boston Children’s Hospital, attributes to everyone’s early focus on older adults, who were most likely to become hospitalised or die. “We dismissed it as COVID doesn’t affect kids seriously, but now we realise they can have these lingering symptoms,” she says.

Quote from THHuxleynew

Nor am I (not sure about Zeus) lauding [masks] without specific context.

The context is obvious. Anything that reduces R0 is a good thing. As even the most scientifically illiterate Rossi devotee should be able to understand...

For example, lets say masks only reduce transmission by a measly 1% per day.

At the end of the year we will see 37 times less death, hospitalisations etc etc.

Marginal gains work.

I have a feeling that Mark U. and others of his ilk, consider themselves "Libertarians" *. I have some sympathy - I'm not a fan of various laws that impinge on my personal freedoms either.

But I don't consider him, and people like him, to be real Libertarians, as they seem to be unaware of the basic tenet of the philosophy:

"The only purpose for which power can be rightfully exercised over any member of a civilized community, against his will, is to prevent harm to others."   John Stuart Mill

*When actually, they are "selfish A-holes".

Family who refused Covid vaccine die within days of each other

A mother, father and son who all refused to take a Covid-19 vaccine have died within seven days of each other.

www.newsletter.co.uk

A mother, father and their adult son who all refused to take a Covid-19 vaccine have died within seven days of each other.

Francis Goncalves, a chef from Cardiff in Wales, blamed anti-vaxxers for spreading the kind of misinformation that he said “confused” his parents and ultimately influenced their decision not to take a vaccine when it was offered to them.

Mr. Goncalves explained how his father Basil, 73, and Charmagne, 65, as well as younger sibling Shaul, 40, who were living in Portugal, started feeling unwell after a family meal together - all three were dead within two weeks.

“They got caught up in a lot of the anti-vaccination propaganda,” explained Mr. Goncalves,

“It preys on people who are afraid and they fall into the trap. The message I want to get out is why would the government want to hurt you by giving you a vaccine? What is the purpose behind it? I’ve spoken to so many people who are terrified of the vaccine and it costs lives.

from another link

Francis said his brother was the "healthiest person" he knew and believes the vaccine would have saved his life, adding: "If he wasn't working out in the gym or running, he was going on walks. He hadn't drunk in 15 years and ate a whole foods plant-based diet."

These stories of families dying may just be coincidence - or may indicate some genetic predisposition towards COVID danger. That is likely. It is also why W's "if you are healthy and young you have no risk" suggestions don't work.