Display MoreSo the question is: do we have any RCT data showing this claimed prophylatic effect?
The problem here is that when a drug only confers a prophylactic effect, so you give it to lots of not ill people in the hope they will stay not ill, is more difficult to evaluate (you need higher numbers) and also the cost of any deleterious effects is much high, because you are giving the drug to many people who do not need it.
HCQ is used for malaria prophylaxis in some places. So it is not an insurmountable barrier, especially for places more accepting of small risks for some gain. In the West you would want very good evidence of the gain.
Where is it? You'd hope we had it by now.
Let's choose just one --
"Healthcare workers & SARS-CoV-2 infection in India: A case-control investigation in the time of COVID-19"