By the time a person is in the ICU, the live virus is often gone, and the patient is dealing with the fallout of viral debris and inflammation.
Maybe I missed this current knowledge, but does this indicate, that the ICU staff may not require anymore strong protection (or no at all) when they take care of the severely sick patients, because they are not infectious anymore? Would be a huge relief for their working conditions…
A CDC report published earlier this month indicates that 85 percent of breakthrough deaths in the U.S. through August occurred in adults 65 and older.
This (only 85%) is a very bad sign as usually 97% of CoV.19 deaths happen in this group! This looks like enhancing the death rate for younger. (First seen in Israel!)
The weekly age-standardised mortality rates (ASMRs) for deaths involving COVID-19 were consistently lower for people who had received two vaccinations compared with one or no vaccinations.
You still don't get it. 60% in the vaccine group are protected (25 better) by a natural infection. So you have to divide vaccine protection figures by 2.5. g. in India the factor is 4.
Maybe I missed this current knowledge, but does this indicate, that the ICU staff may not require anymore strong protection (or no at all) when they take care of the severely sick patients, because they are not infectious anymore?
I don't think so. Usually the patients are in different states. Maximum virus shedding usually is day 1 before first symptoms! But as long as the respiratory tract is affected the patient will shed virus.
Long time ICU cases could be an other game. But here the personal can protect themselves with a weekly Ivermectin dose.
This should put the nail in the coffin for eradicating SARS cov2 as we also have confirmed animal to human transmission of the virus. Big pool of virus out there! Early outpatient treatment will bring Covid to it's knees! Virus has become vaccine resistant
Genomic investigation of a household SARS-CoV-2 disease cluster in Arizona involving a cat, dog, and pet owner
Highlights
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Two companion animals from the same household tested positive for SARS-CoV-2.
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Sequencing of the cat, dog, and pet owner samples revealed identical viral genomes.
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Phylogenetic analysis shows that the viral genomes fall into a locally circulating clade of B.1.575.
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This is the first known report of the B.1.575 lineage in companion animals.
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Evidence of viral transmission from a pet owner to at least one pet in the same household was identified through genomic sequencing.
Abstract
Arizona's COVID-19 and Pets Program is a prospective surveillance study being conducted to characterize how SARS-CoV-2 impacts companion animals living in households with SARS-CoV-2-positive individuals. Among the enrolled pets, we identified a SARS-CoV-2-infected cat and dog from the same household; both animals were asymptomatic but had close contact with the symptomatic and SARS-CoV-2-positive owner. Whole genome sequencing of animal and owner specimens revealed identical viral genomes of the B.1.575 lineage, suggesting zoonotic transmission of SARS-CoV-2 from human to at least one pet. This is the first report of the B.1.575 lineage in companion animals. Genetically linking SARS-CoV-2 between people and animals, and tracking changes in SARS-CoV-2 genomes is essential to detect any cross-species SARS-CoV-2 transmission that may lead to more transmissible or severe variants that can affect humans. Surveillance studies, including genomic analyses of owner and pet specimens, are needed to further our understanding of how SARS-CoV-2 impacts companion animals.
Plant hunter
A conversation with one of the world's leading ethnobotanists, Dr. Cassandra Quave, who has just published an engaging, candid, and action-packed memoir.
Aspirin -- that ever-present drug in nearly everyone's medicine cabinet -- comes to us, as you may know already, from the willow tree. And certain life-saving medicines that are effective against malaria come from cinchona and wormwood. Indeed, a great deal of medicine comes directly from the natural world...and yet, sadly, the potential of medicinal plants is often downplayed or even ignored by experts and lay people alike. On this edition of ST Medical Monday, we chat with one of the world's leading ethnobotanists, Dr. Cassandra Quave. Her new memoir recounts her ongoing quest to develop new ways to fight illness and disease through the healing powers of plants. Her book is "The Plant Hunter: A Scientist's Quest for Nature's Next Medicines." As was noted of this candid and adventure-packed autobiography in the journal Science: "Quave remains determined, resourceful, and cognizant of the alliances that have enabled her life's work.... [She] exhibits a deep humanity and humility in her writing. This, along with her thrilling adventures -- often with children in tow -- spurs the reader on. In the end, she succeeds in demonstrating that plants are an underutilized resource for drug discovery and in communicating the many joys and challenges that accompany a career in science."
29 minute question and answer audio
A judge has suspended Chicago’s COVID-19 vaccination requirement for police officers
The ruling Monday is a major victory for the police unions which sued the city over vaccine requirements.
A Cook County judge on Monday suspended the city of Chicago’s policy requiring that all of its police officers be vaccinated against COVID-19 by the end of the year.
The ruling is a major victory for police unions, who have held that the city’s COVID-19 vaccine mandate violates their collective bargaining agreements. Judge Raymond Mitchell ruled Monday that the mandate should be halted for police officers until those complaints can be settled in arbitration.
Mitchell’s ruling does not impact other city workers, or other parts of the policy. That means city employees who are not represented by any of the four police unions will still have to be vaccinated by Dec. 31, 2021. And all police officers are still required to report their vaccination status and get tested twice a week if they’re not vaccinated.
Chicago Mayor Lori Lightfoot said at an unrelated news conference Monday afternoon that her office is still reviewing the order, and she hadn’t yet read it. She declined to comment on whether the dispute will be resolved by the end of the year, but contended the “mandate continues.”
“Our lawyers are looking at the judge’s ruling and looking at what our legal options are,” she said. “But what I know is we cannot stop, we absolutely cannot stop. This is about saving people’s lives.”
About 58% of the city’s police force has reported being vaccinated against COVID-19, according to city data. However, about 27% of officers still have not reported their vaccination status at all.
Up until now, much of the public fight over Chicago’s vaccination policy has been over the reporting requirement. John Catanzara, the head of the Chicago Fraternal Order of Police, has vocally opposed the requirement that all workers share whether or not they are vaccinated against COVID-19, calling it an invasion of privacy and a violation of the police contract.
Catanzara repeatedly called for officers to “hold the line” and refuse to share their vaccination status with the city. However, the majority of FOP members went against his wishes and updated their status.
Catanzara said that did not mean officers had largely rejected his strident messaging. Instead, he said he believes most of the union members who did comply had already done so before he started his near-daily calls for disobedience near the end of October.
“There’s still over 3,000 members not in the [vaccine] portal,” Catanzara said at a press conference outside of police headquarters last week. “No one’s stopping them from [sharing their status] voluntarily. They’re intentionally not complying with the portal request and demand period. I think that’s unity.”
Chicago Police Superintendent David Brown said on Monday that 35 officers had been stripped of their police powers for refusing a direct order to provide their vaccination status.
Mitchell’s ruling Monday moves the conversation forward toward the much bigger vaccination deadline of Dec. 31. His order brushed aside the union’s complaints about reporting, calling the requirement “a minimal intrusion” that could be remedied later if an arbiter found the requirement violated the city’s contracts with its police officers.
On the vaccine requirement however, the judge said there would be no possible remedy after the mandatory deadline if the policy was ultimately found to violate the collective bargaining agreements.
“If every union member complied and was vaccinated by December 31 … they would have no grievance to pursue and there would be no remedy an arbitrator could award,” the judge wrote in his order. “An award of back pay or reinstatement cannot undo a vaccine. Nothing can.”
When asked for comment, Mayor Lori Lightfoot’s office indicated she would answer questions at an unrelated 2pm news conference the mayor is holding.
The mayor has contended the vaccination requirement is essential for the health and safety of both the public and city employees themselves. In an impassioned address to aldermen on Friday, she pointed out that four officers have died from COVID-19 since the pandemic began.
“I want to ask those who say they ‘support the police’ — how many more have to die?,” Lightfoot said, specifically responding to a group of aldermen who attempted — and failed Friday — to repeal the mandate.
“The people who are unvaccinated are playing Russian roulette with their life and they’re playing Russian roulette with … the people of this city who have a right to believe that when someone from the city government shows up at their door, they are there to help them and save their life, not imperil it.”
Catanzara, however, has said that the vaccine requirement is not about public health or safety, but instead about Lightfoot’s need for “total control.” He said the police unions have suggested that officers undergo COVID-19 testing before starting each shift.
“If it’s about stopping the spread, then let’s test every day you go to work, not just once a week or twice a week, they said no on face value. So who’s full of crap here?” Catanzara said on Oct. 25.
A vast majority of city employees from other departments have complied with the current order to report their vaccination status — with 32 of 34 city departments having at least 92 percent of employees in compliance.
The mayor’s vaccine mandate has dominated the news for months now after it was announced with few details in August. It faced immediate pushback from the Chicago Federation of Labor, an umbrella organization for unions. The group opposes punitive measures included in the mandate, such as putting employees on no-pay status for not complying.
A week before a previously declared Oct. 15 deadline for all employees to get vaccinated, the mayor eased the mandate, allowing employees to simply report their vaccination status by that date, and allowing unvaccinated employees to test twice-weekly until the end of the year.
Zimbabwe Commences Real-World Ivermectin Study as Early Use Treatment for COVID-19
Back in February of this year, TrialSite chronicled the dramatic, seemingly correlated turnaround of SARS-CoV-2 cases. The government of Zimbabwe gave the green light to importation and widespread use of ivermectin into the southern African country of nearly 15 million people as a home care treatment. Like what was observed in Uttar Pradesh India, the consistent use of ivermectin here was associated with a dramatic turnaround in cases toward the beginning of 2021. TrialSite shared more details of this story from an interview with Dr. Jackie Stone. Advocating for the use of the drug, she reported tremendous real-world results. However, conflict ensued as to the authorization of the drug and use off-label as the medical society there not only resisted but also pursued Dr. Stone’s physician’s license. The country staved off another even bigger surge of cases from June through the August with a rapid turnaround from using ivermectin. The country’s regulatory body issued a formal circular authorizing real-world access to ivermectin to treat COVID-19.
Much of the use of Ivermectin in Zimbabwe was done at home instead of the hospitals as local doctors were given an informal reprieve from scrutiny. Now, local media (The Herald) reports that the nation’s drug regulator, the Medicines Control Authority of Zimbabwe (MCAZ) is officially allowing three private hospitals and three private pharmacies physicians to prescribe ivermectin as an early-onset treatment for COVID-19. Interestingly, the piece from The Herald cited that this was the case, despite growing evidence for “zero effect” on COVID-19. TrialSite reminds all that this depends on the point of view, as over 60 studies showcase some positive data points for the use of ivermectin. For an objective point of view, see the following fact sheet.
Interestingly, the local Zimbabwe piece emphasized ivermectin is “wildly popular among Americans who refuse to get vaccinated” which is an overstatement, as many proponents of ivermectin in America are vaccinated and simply seek safe and effective early treatment options for breakthrough infections.
Regardless the MCAZ projects and public relations officer, Mr. Shingai Gwatidzo, shared that the approval was granted to the Avenues Clinic, Mater Dei Hospital, Datlabs Clinic, Kentlink Pharmacies, Village Pharmacy and Racecourse Pharmacy.
Part of an authorized use reported by TrialSite, the greenlighting of ivermectin is supported with a formal real world data collection and tracking study, reports Mr. Gwatidzo.
Specifically, the authorities require any authorized use of the drug be associated with the “submission of monthly reports detailing patient specific therapeutic outcomes in terms of safety and efficacy.” Apparently MCAZ officials are running a formal, real-world study to evaluate for themselves the efficacy of the product.
Regulatory Framework for Real-World Use
A review of the MCAZ website finds the regulatory agency has declared a formal off-label real-world ivermectin data collection initiative titled “Monitoring and Data Collection Framework for Limited Off-label use of Prescription Preparation Ivermectin in COVID-19 Authorized in Terms of Section 75 of the Medicines and Allied Substances Control Act (Chapter 15:03)”.
This regulatory declaration follows the World Health Organization (WHO) protocol to only use ivermectin in research settings, while offers real-world use for actual care. As part of the program MCAZ establishes rules for importation, production, and distribution.
TrialSite has reported that to avoid pressure from the World Health Organization (WHO), low and middle-income countries (LMICs) must not promote the use of ivermectin unless its for research.
for 2 months of iffy protection Pfizer is taking the public to the bank!
Pfizer raises Covid-19 vaccine sales forecast to $36bn for 2021
Pfizer raises Covid-19 vaccine sales forecast to $36bn for 2021 | Pfizer | The Guardian
Maybe I missed this current knowledge, but does this indicate, that the ICU staff may not require anymore strong protection (or no at all) when they take care of the severely sick patients, because they are not infectious anymore? Would be a huge relief for their working conditions…
Nah, most would feel better wearing protection, not removing it. Human nature.
Just look at the CDC site. Over 85 percent of serious covid cases no longer yield "replication competent" virus at the 10 day mark after symptom onset. At 15 days it's 95 percent.
Maybe I missed this current knowledge, but does this indicate, that the ICU staff may not require anymore strong protection (or no at all) when they take care of the severely sick patients, because they are not infectious anymore?
No. More than 3,600 U.S. healthcare workers died of COVID in 2020. The quote above is "the virus is often gone." Not always, often. Treating any infectious disease is dangerous.
for 2 months of iffy protection Pfizer is taking the public to the bank!
The statistics from Japan and every other highly vaccinated country show that you are wrong. It is not "iffy" and it lasts longer than 2 months. Stop lying. I would say stop the bullshit, but your statement is so far out, so destructive, and so obviously wrong, I suppose you must know better. So it is a lie.
I posted a study that a supplement prevents Covid, killing on contact. It's called nitric oxide.
Would that be in a petri dish?
Abstract
Arizona's COVID-19 and Pets Program is a prospective surveillance study being conducted to characterize how SARS-CoV-2 impacts companion animals living in households with SARS-CoV-2-positive individuals. Among the enrolled pets, we identified a SARS-CoV-2-infected cat and dog from the same household; both animals were asymptomatic but had close contact with the symptomatic and SARS-CoV-2-positive owner.
Up here in Canada were are injecting zoo animals. We just love the shots that much, we can't get enough!
Although, some crazy researchers are reporting that vaccinations (not of animals but humans no less) aren't working to reduce recent cases:
This should put the nail in the coffin for eradicating SARS cov2 as we also have confirmed animal to human transmission of the virus. Big pool of virus out there! Early outpatient treatment will bring Covid to it's knees! Virus has become vaccine resistant
This is wrong for several reasons:
Up here in Canada were are injecting zoo animals.
This is happening in the U.S., Japan and other countries. Places like mink farms are doing it worldwide. All zoo primates should be vaccinated. It would be good if wild chimpanzees could be vaccinated. Since the COVID pandemic began, all human contact with wild chimpanzees has been curtailed, and nature preserves in Africa have been closed to tourists, according to Jane Goodall. In 1966, Goodall stopped a polio epidemic among Tanzanian chimps by hiding an oral polio vaccine in bananas, according to the National Geographic. It would be great if an oral COVID vaccine is developed, and it can be used on chimpanzees.
Nitric oxide as a therapeutic option for COVID-19 treatment: a concise perspective
Nitric oxide as a therapeutic option for COVID-19 treatment: a concise perspective In the prevailing coronavirus disease-2019 (COVID-19) times, scientists are eager to develop vaccines against COVID-19, and careful measures are being taken to… pubs.rsc.org
I followed this link. Its an abstract which says:
In the meantime, nitric oxide (NO) is also under clinical trials to find its potentiality as anticoronavirus.
Yet somehow you, Dr Fm1 (We.B), is able to extrapolate that statement into:
L arginine it converts [into NO] almost immediately and dispersed into the blood stream. The pandemic is over, over the counter supplents are available to everyone.
and…
By supplementing vitamin D and L-arginine daily you won't get Covid. Period!
And you want to be taken seriously? LOL.
You still don't get it. 60% in the vaccine group are protected (25 better) by a natural infection.
Bullshit. Please provide evidence that 60% of British people have had Covid.
Display MoreUp here in Canada were are injecting zoo animals. We just love the shots that much, we can't get enough!
Although, some crazy researchers are reporting that vaccinations (not of animals but humans no less) aren't working to reduce recent cases:
https://europepmc.org/article/pmc/pmc8481107
Increases in COVID-19 are unrelated to levels of vaccination across 68 countries and 2947 counties in the United States.
That is not what the headline says. I think, as many antivaxxers do, you are confusing causation with correlation.
Display MoreI followed this link. Its an abstract which says:
In the meantime, nitric oxide (NO) is also under clinical trials to find its potentiality as anticoronavirus.
Yet somehow you, Dr Fm1 (We.B), is able to extrapolate that statement into:
and…
And you want to be taken seriously? LOL.
You might want to pull your head out of your arse dimwit
Nitric Oxide Nasal Spray for COVID-19 to Be Distributed to India and Other Asia Markets
Glenmark Pharmaceuticals has partnered with SaNOtize to manufacture, market, and distribute NONS to India, Singapore, Malaysia, Hong Kong, and more.
SaNOtize and Glenmark Pharmaceuticals announced on August 2, 2021 an exclusive long-term strategic partnership to manufacture, market, and distribute SaNOtize’s nitric oxide nasal spray (NONS) for COVID-19 treatment to India and other Asian markets, including Singapore, Malaysia Hong Kong, Taiwan, Nepal, Brunei, Cambodia, Laos, Myanmar, Sri Lanka, Timor-Leste, and Vietnam.
NONS were found to be a safe and effective antiviral treatment to prevent the transmission of COVID-19, shorten its course, and reduce the severity of symptoms in SaNOtize’s March 2021 clinical trials.
NONS is designed to kill the COVID-19 virus in the upper airways, preventing it from incubating and spreading to the lungs. It is based on nitric oxide, which has proven anti-microbial properties and a direct effect on SARS-CoV-2.
Bullshit. Please provide evidence that 60% of British people have had Covid.
It is ironic. The easiest way to test for prior infection is N-antibody status - since the virus causes them and the vaccine does not. This is low in the UK.
In order to argue for much higher prior infection rates (which they need to explain away real-world high vaccine efficacy) they need to agree that antibody presence in blood is not the only thing that delivers immunity. This is of course true. Unfortunately they then cannot use the dramatic reduction in neutralising antibodies at 6 months after vaccination as a sign that vaccine protection is time limited.
In fact we have evidence now of protection against hospitalisation staying constant up to 5 months out (the last time monitored in a recent study), even though protection against catching of transmitting infection does seem to reduce. Given the graph constant for 5 months there is a good chance those vaccinated will have pretty good protection from delta for a long time. Pretty good is not perfect, and protection is less good for those oldest.
